Identification of Soluble Epoxide Hydrolase Inhibitors from the Seeds of Passiflora edulis Cultivated in Vietnam

To Dao Cuong,Hoang Thi Ngoc Anh,Tran Thu Huong,Pham Ngoc Khanh,Vu Thi Ha,Tran Manh Hung,김영호,Nguyen Manh Cuong 한국생약학회 2019 Natural Product Sciences Vol.25 No.4

Soluble epoxide hydrolases (sEH) are enzymes present in all living organisms, metabolize epoxy fatty acids to 1,2-diols. sEH in the metabolism of polyunsaturated fatty acids plays a key role in inflammation. In addition, the endogenous lipid mediators in cardiovascular disease are also broken down to diols by the action of sEH that enhanced cardiovascular protection. In this study, sEH inhibitory guided fractionation led to the isolation of five phenolic compounds trans-resveratrol (1), trans-piceatannol (2), sulfuretin (3), (+)-balanophonin (4), and cassigarol E (5) from the ethanol extract of the seeds of Passiflora edulis Sims cultivated in Vietnam. The chemical structures of isolated compounds were determined by the interpretation of NMR spectral data, mass spectra, and comparison with data from the literature. The soluble epoxide hydrolase (sEH) inhibitory activity of isolated compounds was evaluated. Among them, trans-piceatannol (2) showed the most potent inhibitory activity on sEH with an IC50 value of 3.4 mM. This study marks the first time that sulfuretin (3) was isolated from Passiflora edulis as well as (+)-balanophonin (4), and cassigarol E (5) were isolated from Passiflora genus.

Determinants of Intra-Industry Trade between Vietnam and Countries in TPP

NGUYEN, Ha Minh,QUAN, Binh Quoc Minh,LE, Huong Van,TRAN, Thinh Van Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.1

Intra-industry trade (IIT) has played an important role in international trade of Vietnam as a result of rapid growth of the country. This article investigates the level of IIT between Vietnam and 11 trading partners in Trans-Pacific Partnership (TPP) over the period 2000-2014. Although there have been a large number of empirical researches contributed to the determinants of IIT, most of them only pay attention on developed countries where the trade flows are similar due to similar demand structure and production technology. Until now, there is no study on intra-industry trade between Vietnam and countries in TPP that Vietnam recently signed a trade agreement in early 2016. IIT is measured by the Grubel-Lloyd index. The index shows that the extent of intra-industry trade between Vietnam and the trading countries is not high due to the level of economic development and the market size. The determinants of IIT are examined using a panel regression model. In the empirical analysis, the results indicate that Vietnam's intra-industry trade is positively correlated with country size, while it is negatively correlated with income dissimilarity, the trade openness, and geographical distance. This study contributes to the new theoretical trade theory on the evidence of developing country's IIT.

Predicting Financial Distress Distribution of Companies

Giang Huong VU(Giang Huong VU ),Chi Thi Kim NGUYEN(Chi Thi Kim NGUYEN ),Dang Van PHAM(Dang Van PHAM ),Diu Thi Phuong TRAN(Diu Thi Phuong TRAN ),Toan Duc VU(Toan Duc VU ) 한국유통과학회 2022 유통과학연구 Vol.20 No.10

Purpose: Predicting the financial distress distribution of an enterprise is important to warn enterprises about their future. Predicting the possibility of financial distress helps companies have action plans to avoid the possibility of bankruptcy. In this study, the author conducted a forecast of the financial distress distribution of enterprises. Research design, data and methodology: The forecasting method is based on Logit and Discriminant analysis models. The data was collected from companies listed on Vietnam Stock Exchange from 2012 to 2020. In which there are both companies suffer from financial distress and non-financial distress. Results: The forecast analysis results show that the Logistic model has better predictability than the Discriminant analysis model. At the same time, the results also indicate three main factors affecting the financial distress of enterprises at all three research stages: (1) Liquidity, (2) Interest payment, and (3) firm size. In addition, at each stage, the impact of factors on financial distress differs. Conclusions: From the results of this study, the author also made several recommendations to help companies better control company operations to avoid falling into financial distress. Adjustments to current assets, debt, and company expansion considerations are the most important factors for companies.

베트남의 한국학 및 한국어교육 관련 동향 -하노이국립대학교 외국어 대학을 중심으로-

( Tran Thi Huong ) 이화여자대학교 한국문화연구원 2020 한국문화연구 Vol.39 No.-

Nowadays, Korean language education in Vietnam has been flourishing not only in universities but also in high schools and Middle School. In recent years, the number of Korean teachers and learners has increased dramatically so it can be said that Vietnam is a country that has been developing brilliantly in the field of Korean language teaching among Southeast Asian countries. This paper will review the situation of teaching Korean language at major universities and educational institutions in Vietnam. In other words, it can be affirmed that Vietnam's education and research branch in Korean language and Korean studies has grown beyond the stable threshold and is undergoing a drastic change. The paper also surveyed the curriculum of some typical Korean faculties in Vietnam. From there, analyzing the number of credits in Korean language and the subjects of Korean studies, finding out the common points and characteristics of the Korean studies of Vietnam. The paper also proposed directions and solutions for the development of Korean language education and Korean studies in Vietnam in the future. (Focus to Vietnam National University- University of Languages and International Studies)

Influence of flowrates to a reverse electro-dialysis (RED) stack on performance and electrochemistry of a microbial reverse electrodialysis cell (MRC)

Huong V. H. Tran,구본영,손성훈,김준혁,정석희 대한환경공학회 2018 대한환경공학회 학술발표논문집 Vol.2018 No.11

DNA Methylation Changes Following 5-azacitidine Treatment in Patients with Myelodysplastic Syndrome

Tran, Huong Thi Thanh,Kim, Hee Nam,Lee, Il-Kwon,Kim, Yeo-Kyeoung,Ahn, Jae-Sook,Yang, Deok-Hwan,Lee, Je-Jung,Kim, Hyeoung-Joon The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.2

<P>DNA methyltransferase inhibitor, 5-azacitidine (AC) is effective in myelodysplastic syndromes (MDS) and can induce re-expression in cancer. We analyzed the methylation of 25 tumor suppressor genes in AC-treated MDS. Hypermethylation of <I>CDKN2B</I>, <I>FHIT</I>, <I>ESR1</I>, and <I>IGSF4</I> gene was detected in 9/44 patients. In concordance with the clinical response, a lack of or decreased methylation in 4 patients with hematologic improvements and persistent methylation in 4 others with no response was observed. The mRNA expression of <I>CDKN2B</I>, <I>IGSF4</I>, and <I>ESR1</I> was significantly reduced in MDS. Our results suggest that methylation changes contribute to disease pathogenesis and may serve as marker to monitor the efficacy of treatments.</P>

Anode biofilm maturation time, stable cell performance time, and time-course electrochemistry in a single-chamber microbial fuel cell with a brush-anode

Huong V. H. Tran,Eojin Kim,Sokhee P. Jung 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.106 No.-

For accurate and reproducible MFC experiments, it is important to know when MFCs produce stable cellperformance. Herein, four replicate single-chamber MFCs were tested for 17 weeks by using polarizationand cyclic voltammetry (CV) tests. The strong MFCs (#2,4,3) showing continuous performance enhancementinitially (3rd–9th week) produced good subsequent performance (9th–17th week). The weak MFC-1experienced a performance drop initially and showed bad subsequent performance. All the MFC performancebecame stable after 9 weeks. The strong MFCs produced power 2.8–3.6 times higher and anoderesistance 7.5–23.9 times lower than the weak. However, their cathode resistances were similar. CVresults showed anodic current production increased continuously in all MFCs, indicating anode biofilmskept growing;, MFC performance did not increase accordingly. Anodic CVs had a typical S-shape curve,but those of MFC-1 showed straight lines from the 9th week. The weak MFC-1 showed smaller CV currentsand thinner CV curves than those of the strong MFCs. In MFC-1, at the 17th week, the anode resistancereduced by 47%, anodic current and cell performance increased. Regression analysis showed anode resistancewas a limiting factor of the weak MFC and cathode resistance was that of the strong MFCs. Thisresult suggests one operating principle: improve anodes in weak MFCs and cathodes in strong MFCs toachieve better MFC performance.

DNA Methylation Changes Following 5-azacitidine Treatment in Patients with Myelodysplastic Syndrome

Huong Thi Thanh Tran,김희남,이일권,김여경,안재숙,양덕환,이제중,김형준 대한의학회 2011 Journal of Korean medical science Vol.26 No.2

DNA methyltransferase inhibitor, 5-azacitidine (AC) is effective in myelodysplastic syndromes (MDS) and can induce re-expression in cancer. We analyzed the methylation of 25 tumor suppressor genes in AC-treated MDS. Hypermethylation of CDKN2B, FHIT, ESR1,and IGSF4 gene was detected in 9/44 patients. In concordance with the clinical response, a lack of or decreased methylation in 4 patients with hematologic improvements and persistent methylation in 4 others with no response was observed. The mRNA expression of CDKN2B, IGSF4, and ESR1 was significantly reduced in MDS. Our results suggest that methylation changes contribute to disease pathogenesis and may serve as marker to monitor the efficacy of treatments.

베트남 지역 세종학당의 운영 현황과 향후 발전을 위한 제언

Tran Thi Huong,이윤진(Lee, Yun-jin) 전남대학교 한국어문학연구소 2017 전남대학교 한국어문학연구소 학술지 어문논총 Vol.- No.30

본고는 2007년 최초 설립 이래 지속적으로 확대되고 있는 한국어 국외 보급 전문기관인 ‘세종학당’에 관심을 두고, 성공적인 운영 기관의 한 사례로 베트남 지역의 하노이2 세종학당을 중심으로 고찰한 논의이다. 먼저 2장에서는 세종학당 관련 기존 성과를 전반적으로 검토한 데 이어 베트남 지역의 한국어 교육과 세종학당에 대한 선행 연구를 개관하였다. 3장에서는 본고의 연구 대상인 하노이2 세종학당의 개요 및 운영 현황을 파악하고 이를 토대로 4장에서는 향후 발전 방안에 대한 시사점을 논하였다. 개별 세종학당들의 성공적인 운영 사례를 발굴하고 면밀히 파악하는 작업은 세계 곳곳 세종학당의 내적 기반을 공고히 하고 현지 실정에 최적화된 세종학당의 모습을 모색하는 데 기초 자료로 삼을 수 있다는 측면에서 본고의 의의가 있다. This paper discusses Sejong Institute, the specialized organization promoting Korean language teaching and learning overseas, which has been continuously expanding since its establishment in 2007. In particular, the discussion focuses on Sejong Institute Hanoi 2 in Vietnam as an example of successful institute operation. In Chapter 2, we review in general the established results related to Sejong Institute and then examine previous studies on Korean language education and Sejong Institute in Vietnam. In Chapter 3, we look at the outline and the current operation conditions of Sejong Institute Hanoi 2, the subject of this study, and based on this, discuss in Chapter 4 the implications for future development plans. The significance of this paper lies in the fact that the work of finding and carefully understanding cases of successfully operated individual Sejong Institute centers can provide the basic material for strengthening the internal foundation of Sejong Institute centers around the world and for finding the form of Sejong Institute that is optimized for local circumstances.

베트남에서의 한국학 교육 및 연구 현황과 방향

Tran Thi Huong 국제한국어교육학회 2020 한국어 교육 Vol.31 No.2

In recent years, Korean language education in Vietnam has been flourishing not only in universities but also in high schools and foreign language centers. Comparing to 10 years ago, the number of Korean teachers and learners has increased dramatically. Currently, it can be said that Vietnam is a country that has been developing brilliantly in the field of Korean language teaching among Southeast Asian countries. This paper will review the situation of teaching Korean language at major universities and educational institutions in Vietnam. In other words, it can be affirmed that Vietnam's education and research branch in Korean language and Korean studies has grown beyond the stable threshold and is undergoing a drastic change. The paper also proposed directions and solutions for the development of Korean language education and Korean studies in Vietnam in the future.