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- 저자 : Huang Zifeng (검색결과 4 건)
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Ziwuliuzhu Acupuncture Modulates Clock mRNA, Bmal1 mRNA and Melatonin in Insomnia Rats
Huang Ao,Xiao Gefang,Chen Yiliu,Hu Zuying,Lee Pin-Hsuan,Huang Yusen,Zhuang Zifeng,Zhang Yuling,Qing Peng,Zhao Canghuan 사단법인약침학회 2023 Journal of Acupuncture & Meridian Studies Vol.16 No.3
Background: In clinics, Ziwuliuzhu acupuncture is widely considered an effective method of treating insomnia; however, there is currently limited information available regarding its possible mechanisms. Although the method of Ziwuliuzhu acupuncture possesses a unique rhythmic pattern. Objectives: In this study, we have creatively combined the traditional Chinese medicine of Ziwuliuzhu with a modern biological rhythm to investigate the internal mechanism of insomnia. Methods: Pathological tissue from the hypothalamus was analyzed using hematoxylin– eosin staining. The level of TNF (tumor necrosis factor)-α in the SCN (suprachiasmatic nucleus) area of the hypothalamus was detected in situ using the TUNEL fluorescence staining assay. The concentration of hypothalamic melatonin was detected using the enzyme-linked immunosorbent assay (ELISA). The mRNA expression of Clock and Bmal1 was measured using RT-qPCR. Results: In the Ziwuliuzhu acupuncture groups, the structural damage in the hypothalamic neurons was alleviated compared to the model group and the expression of inflammatory factors was reduced. The mRNA expression levels of Clock and Bmal1 were significantly increased (p < 0.05). The concentration of melatonin was significantly increased (p < 0.001). Although there were no significant differences between the treatment groups (diazepam group, Nazi group, Najia group, and routine group) (p > 0.05). Conclusion: Ziwuliuzhu acupuncture alleviated neuronal damage and modulated the inflammatory reaction in the hypothalamus of rats with insomnia. Moreover, Ziwuliuzhu acupuncture increased the expression levels of Clock and Bmal1 mRNA, and MT content. This study has potentially highlighted one of
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Guaranteed Cost Optimal Control of High-speed Train with Time-delay in Cruise Phase
Xiangjin Tian,Deqing Huang,Na Qin,Zifeng Gong,Qingyuan Wang 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.9
In this paper, a novel guaranteed cost control scheme that takes into account state time-delay and parametric uncertainties is proposed for high-speed train (HST) optimal operation control. First, a linear dynamic model of HST is built, where the basic and additional resistances, in-train force, train effort as well as state time-delay are addressed explicitly. Second, an operation criterion considering the velocity tracking, operation safety and running cost is established. Third, a guaranteed cost controller is then designed to realize the optimal control with tradeoff among the multiple objectives. To the best knowledge of the authors, it is the first time to address the velocity tracking, the operation safety and the running cost simultaneously while considering both state time-delay and parametric uncertainties, which corresponds to a more practical scenario in high-speed train control. At last, simulation is carried out to validate the effectiveness of the proposed control scheme under different delay degrees.
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Habib Ullah Khan Jadoon,Deqing Huang,Na Qin,Zifeng Gong 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.8
The fault and disturbances estimation has an important role in the modern traction railway system. This paper proposes a unique method for the real-time robust sensor fault detection and unknown bounded disturbances estimation of high switching frequency single-phase pulse width modulation (PWM) rectifier. The new state observer is designed for open-circuit sensors fault for single-phase PWM rectifier. The digital realization method is used to minimize the observer fluctuation in presence of fault with and without external disturbance. The fault diagnosis approach constitutes on threshold establishment with respect to residual generation based on observer and estimator. The impact of uncertainties is reduced and the convergence speed of fault estimation and accuracy is improved by H∞ performance level. The extensive simulations are implemented to validate the effectiveness of the proposed algorithm. From the presented results, the performance of the proposed method is illustrated along with the fault isolation and disturbance estimator.
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Hu Kui,Ma Xubo,Zhang Teng,Ma Xuan,Huang Zifeng,Chen Yixue 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.8
How to generate the precise broad group cross section is important for the fast reactor design. In this study, a fast reactor multi-group cross-section generation code MGGC2.0 are developed in-house for processing ultrafine group MATXS format library. Validation and verification are performed for MGGC2.0 code by applying the benchmarks of ICSBEP handbook, and the results of MGGC2.0 agree well with that of MCNP. The consistent PN method with critical buckling search is in good agreement that condensed with TWODANT flux and flux moment for the inner core and outer core region. For the radial blanket and reflector, two region approximation method has been applied in MGGC2.0 by using collision Probability Method neutron flux solver. The RBEC-M benchmark was used to verify the power distribution calculation, and the relative error of power distribution comparison with the reference are less than 0.8% in the fuel region and the maximum relative error is 5.58% in the reflector region. Therefore, the precise broad cross section can be generated by MGGC2.0 for fast reactor
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