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- 저자 : Horie, S. (검색결과 292 건)
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Horie, Yukihiro,Meguro, Akira,Kitaichi, Nobuyoshi,Lee, Eun Bong,Kanda, Atsuhiro,Noda, Kousuke,Song, Yeong Wook,Park, Kyung Sook,Namba, Kenichi,Ota, Masao,Inoko, Hidetoshi,Mizuki, Nobuhisa,Ishida, Susu Oxford University Press ; Distributed by Mercury I 2012 Rheumatology Vol.51 No.6
<P>Beh?et's disease is one of the major aetiologies of uveitis causing blindness in Asian countries. A genome-wide association study identified six microsatellite markers as disease susceptibility loci for Japanese patients with Beh?et's disease. To confirm our recent results, these microsatellite markers were examined in a Korean population as a replication study.</P>
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HORIE Norichika 서울대학교 일본연구소 2018 일본비평 Vol.- No.18
In Japan, “power spot” refers to a place where spiritual power, energy, and strength, which are generally invisible, are strongly experienced. This word appeared in the mid of 1980s, and by the 2000s it was believed that there were many power spots in shrines. Since the “power spot” boom in 2009, propaganda for worldly profits started to appear. Previous researches focused on pointing out deviations from shinki (神気) belief through information analysis of mass media. In this article, I analyzed contents of internet blog articles on power spot experiences based on four factors – physical effect, psychological effect, parapsychological effect, and worldly profit. These visitors expressed that they received an impression that they were invited to the place of sedative actions, stimulant actions, and mysterious feelings through the senses of water, light, sound, temperature, wind, etc., and that they obtained “power” by associating it with meta-waves of electromagnetic waves or energy. Some people constituted extrasensory perceptions in their meditative state and expressed in poetic images. At first, visitors appeared as if they were pursuing for worldly profits, but in effect they were internally obtaining “psychological profits” that improved their perceptions and responses of life problems. Finally, I would like to point out that factors of shinki belief, worldly profit, and nature worship coexist in the same place by examining the example of Ōmiwa Shrine. Power spot experience may be a deviation from shinki belief, but unlike the pursuit of worldly profits, visitors seem to be able to discover authenticity through the practice of nature worship.
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Occupational Health Policies on Risk Assessment in Japan
Horie, Seichi Occupational Safety and Health Research Institute 2010 Safety and health at work Vol.1 No.1
Industrial Safety and Health Law (ISH Law) of Japan requires abnormalities identified in evaluations of worker health and working environments are reported to occupational physicians, and employers are advised of measures to ensure appropriate accommodations in working environments and work procedures. Since the 1980s, notions of a risk assessment and occupational safety and health management system were expected to further prevent industrial accidents. In 2005, ISH Law stipulated workplace risk assessment using the wording "employers shall endeavor." Following the amendment, multiple documents and guidelines for risk assessment for different work procedures were developed. They require ISH Laws to be implemented fully and workplaces to plan and execute measures to reduce risks, ranking them from those addressing potential hazards to those requiring workers to wear protective articles. A governmental survey in 2005 found the performance of risk assessment was 20.4% and common reasons for not implementing risk assessments were lack of adequate personnel or knowledge. ISH Law specifies criminal penalties for both individuals and organizations. Moreover, under the Labor Contract Law promulgated in 2007, employers are obliged to make reasonable efforts to ensure employee health for foreseeable and avoidable risks. Therefore, enterprises neglecting even the non-binding provisions of guidelines are likely to suffer significant business impact if judged to be responsible for industrial accidents or occupational disease. To promote risk assessment, we must strengthen technical, financial, and physical support from public-service organizations, encourage the dissemination of good practices to reduce risks, and consider additional employer incentives, including relaxed mandatory regulations.
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Horie, K.,Yamashita, M.,Hayasaka, Y.,Katoh, Y.,Tsutsumi, Y.,Katsube, A.,Hidaka, H.,Kim, H.,Cho, M. Elsevier Scientific Pub. Co., etc.] 2010 Precambrian research Vol.183 No.1
U-Pb zircon geochronology of two Permo-Triassic granites (samples OT-52 and OT-272 with ages of 229+/-8Ma and 256+/-2Ma, respectively) in the Unazuki area, Hida Metamorphic Belt, southwest Japan, revealed the presence of Eoarchean to Paleoproterozoic inheritance. Inheritance is consistent with both samples showing low zircon saturation temperatures for their bulk compositions. In OT-52, dark in CL, low Th/U zircon domains have a mean <SUP>207</SUP>Pb/<SUP>206</SUP>Pb age of 1940+/-17Ma, which is consistent with an age of 1937+/-6Ma for anatexis in the Precambrian Busan gneiss complex in Korea. Eoarchaean inherited zircons with <SUP>207</SUP>Pb/<SUP>206</SUP>Pb ages from ca. 3750 to 3550Ma are common in OT-272 but are few in OT-52, suggesting a source from rocks with affinities to those in the Anshan area in the northeast China part of the North China Craton. On the other hand, a Hida Metamorphic Belt metasedimentary gneiss into which the granites were intruded contains ca. 1840, 1130, 580, 360, 285 and 250Ma zircons (Sano et al., 2000). These ages suggest that the Unazuki Mesozoic granites did not originate from proximal Hida Metamorphic Complex rocks, but instead from unrelated rocks obscured at depth. The predominance of Eoarchean to Paleoproterozoic age components, and the marked lack of 900-700Ma components suggest that the source was the (extended?) fringe of the North China Craton, rather than from Yangtze Craton crust. The Mesozoic evolution of Japan and its linkages to northeast Asia are discussed in the context of these results.
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Recent Advances of Nutritional Physiology and Artificial Diet of the silkworm, Bombyx mori, in Japan
Horie, Yasuhiro 한국잠사학회 1995 한국잠사곤충학회지 Vol.37 No.2
Recently, the cocoon production is reducing very steeply in Japan. The main reason for this cocoon reduction is due to high labor cost and the production expense is apt to rise year by year. Accordingly, the improvement of cocoon productivity by retrenchment of the production expense is intensively required in my country. Therefore, the silkworm rearing on the artificial diet is largely expected as the innovation techniques of sericulture. Since rearing of the silkworm on artificial diets has first been achieved in 1960, and the silkworm larvae were reared throughout all the instars on artificial diets(Fukuda et al., 1960, Ito &Tanaka, 1960). The artificial diets used at this time contained 50% or more of dried, pulverized mulberry leaves as one of the main ingredients, and the composition was rather simple. When reared on these diets, larval growth and development were retarded, small cocoons appeared, and the adults laid only a small number of eggs. At first, we would like to study about nutritional requirement of the silkworm, using the chemically defined diet which prepared artificially. Subsequently, attempts were made to improve the diets by replacement of crude ingredients with possibly purer compounds, as mentioned later. Before giving the details on individual nutrient, I would like to summarize about the outline of utilization flow of various nutrients through the larval-pupal development and these daily quantitative requirements per body weight in the silkworm when they were reared on mulberry leaves.
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Horie, Takeo,Nakagawa, Masashi,Orii, Hidefumi,Tsuda, Motoyuki Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
The anterior brain vesicle of ascidian larvae contains two distinct pigment cells. Ultrastructure of these pigment cells has been shown that the anterior pigment cell is an otolith for perception of gravity and the posterior pigment cell is an ocellus for light reception. The larva has remarkably simple central nervous system (CNS) composed of about 330 cells. We focused to study neural networks of visual systems. In the present paper, we report the whole structure of the photoreceptors of the ascidian larva visualized by an antibody against arrestin. Visual arrestin is the key protein for the termination of phototransduction and one of the abundant proteins in photoreceptors. Recently, we cloned an arrestin homologue gene, Ci-arr and the expression of Ci-arr was found to be restricted to the photoreceptors in the ocellus. To study the whole structure of the photoreceptors in the larva, we prepared an antibody against Ci-Arr. It is found that anti Ci-Arr antibody specifically stains the photoreceptors, including the cell bodies, the axons, and the nerve terminals. The photoreceptor cell bodies lies in row outside the pigment cup which penetrate the pigment cell and is continuous with the outer segments of the photoreceptor cell, inside the concavity of the pigments. The axons form bundle into a single tract. The tract extends toward the midline, where the nerve terminals diverge and seem to form synapses
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Chemoprevention of Prostate Cancer: Soy Isoflavones and Curcumin
Shigeo Horie 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.10
The burden of increasing morbidity and mortality due to prostate cancer imposes a need for new, effective measures of prevention in daily life. The influence of lifestyle on carcinogenesis in Asian men who migrate to Western cultures supports a causal role for dietary, environmental, and genetic factors in the epidemiology of prostate cancer. Chemoprevention, a prophylactic approach that uses nontoxic natural or synthetic compounds to reverse, inhibit, or prevent cancer by targeting specific steps in the carcinogenic pathway, is gaining traction among health care practitioners. Soy isoflavones and curcumin, staples of the Asian diet, have shown promise as functional factors for the chemoprevention of prostate cancer because of their ability to modulate multiple intracellular signaling pathways, including cellular proliferation, apoptosis, inflammation, and androgen receptor signaling. Recent evidence has revealed the DNA damage response (DDR) to be one of the earliest events in the multistep progression of human epithelial carcinomas to invasive malignancy. Soy isoflavones and curcumin activate the DDR, providing an opportunity and rationale for the clinical application of these nutraceuticals in the chemoprevention of prostate cancer.
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