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석호태,곽현철,송승영,송진규,이영욱 대한건축학회 2003 대한건축학회논문집 Vol.19 No.4
This study aims to evaluate the economic performance of infiltration prevention devices for the refrigerated warehouse. It is showed that the cooling loads of refrigerated warehouses is changed by assembling of infiltration prevention devices in a previous study. Space loads and cooling energy costs according to the types of the infiltration prevention devices are analyzed by the DOE-2.1E simulation. Based on the Life Cycle Costs considered the costs of initial construction, repair·replace, cooling energy and operating energy, the probability of reducing energy consumption and application of infiltration prevent devices in vestibule of refrigerated warehouse is founded.
전자장치 냉각을 위한 수직수로에서의 열-사이펀 비등실험
전진석,곽호영 중앙대학교 기술과학연구소 1989 기술과학연구소 논문집 Vol.19 No.-
As a result of continuing efforts to improve the circuit performance, the number of devices in the package such as VLSI and the speed of computation has been considerably increased. In fact, during the past two decades the heat flux at the chip level has increased by more than an order of magnitude. Therefore one of the problems faced by engineers who are designing computers, is how to cool the electronic hardware of the computer. The LSI or VLSI chips must be cooled in a manner that the maximum temperature of device junction dose not exceed 85℃ in order in order to keep the reliability. The method of "air cooling" is enough to cool the components such as tube or transistor because of their relatively low heat generation rate. But it is not enough to cool VLSI with such method. Recently "immersion cooling" is studied to solve that problem by many investigators because heat transfer is more effective than others. This paper describes an experimental study on boiling heat transfer between vertical isoflux plates with asymmetric heating with a dielectric fluid, FC-72. This study found that the channel width is not a significant parameter for immersion cooling with FC-72 and that the heat transfer from the vertical plates is more effective than the horizontal plates. And this study demonstrated the possibility of use of "immersion cooling" between narrow PCB's.
정만석,곽현철,석호태 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
Generally, Educational Buildings was selected a direction, plan and scale of building according to the figure of a site. However, In the result. The selection was spent more energy and made every effort to achieve the Thermal Comfort. In the Evaluation of Energy Performance, You must consider whether it will be worthwhile. In this study, we found a difference of Energy Consumption changes according to corridor style, direction, vertical and horizontal location, and roof-space by using DOE-2.1E energy simulation program. Based on this simulation results, found a probability of reducing energy consumption in educational buildings.
RDB 에서의 검색 효율을 위한 XML 문서 저장 모델
권훈,강인석,김정희,곽호영 제주대학교 공과대학 첨단기술연구소 2004 尖端技術硏究所論文集 Vol.15 No.2
The purpose of the paper is design and implementation of Internet-Based Real-Time Admission XML instances for purpose of information exchange are normally stored in the legacy relational database. therefore, integrations with relational database are required for effective XML applications. to support these requirements, virtual decomposition storage or decomposition storage methods which save separates structures of instances to relational database have researched. however, these storage methods contain different information of instance structure and layers which has caused difficulties to process query during search operation as well as increased overheads due to duplicate savings for separate storages. therefore, in this research, additional field of "Eltype" has introduced to previous database schema structure to integrate instance and instance structure, provide .consistent information of layers and propose storage structure to map each field to schema field of relational database. as results, XML instance and structures can be stored together to minimize overheads and required disk space. also, synchronized storage layer structure provides easier processing of search query.
Seok Jin Kim,Young Rok Do,Ho-Sup Lee,Won-Sik Lee,공지현,Jae-Yong Kwak,Hyeon-Seok Eom,Joon Ho Moon,Jun Ho Yi,Jeong-Ok Lee,Jae-Cheol Jo,Deok-Hwan Yang 대한혈액학회 2023 Blood Research Vol.58 No.4
Background Brentuximab vedotin (BV), a potent antibody-drug conjugate, targets the CD30 antigen. In Korea, BV has been approved for the treatment of relapsed or refractory Hodgkin lymphoma (HL), anaplastic large-cell lymphoma (ALCL), and cutaneous T-cell lymphomas, including mycosis fungoides (MF). However, there are limited data reflecting real-world experiences with BV treatment for HL, ALCL, and MF. Methods This was a multicenter, non-interventional registry study of the efficacy and safety of BV in patients with relapsed or refractory CD30-positive lymphoma (CISL1803/BRAVO). Outcomes were determined based on the occurrence of relapse or progression and overall survival after BV treatment. Results A total of 85 patients were enrolled in this study. The median number of BV cycles was 10 (range, 2‒16) in the patients with HL. The objective response rate (ORR) of patients with HL to BV was 85.4% (41/48), comprising 27 complete responses (CRs) and 14 partial responses (PRs). The ORR of ALCL was 88% (22/25), consisting of 17 CRs and five PRs, whereas the ORR of MF was 92% (11/12). At the median follow-up of 44.6 months after BV treatment, the median post-BV progression-free survival of HL, ALCL, and MF patients was 23.6 months, 29.0 months, and 16.7 months, respectively (P =0.641). The most common side effect of BV was peripheral neuropathy; 22 patients (25.9%, 22/85) experienced peripheral neuropathy (all grades). Conclusion The treatment outcomes of patients with relapsed or refractory CD30-positive lymphoma improved with BV treatment, and the safety profile was manageable.
Kwak, Ho-Seok,Han, Jung-Yeol,Choi, June-Seek,Ahn, Hyun-Kyong,Ryu, Hyun-Mee,Chung, Hee-Jung,Cho, Dong-Hee,Shin, Chan-Young,Velazquez-Armenta, E. Yadira,Nava-Ocampo, Alejandro A. Informa Healthcare 2014 Clinical toxicology Vol.52 No.1
<P><I>Objective.</I> Phosphatidylethanol (PEth) is formed endogenously by the direct action of ethanol, and has a half-life long enough to make it a reliable biomarker of alcohol exposure in early pregnancy. In this study, we aimed to characterize PEth blood concentrations to differentiate different levels of alcohol exposure in pregnant women. <I>Methods.</I> The study consisted of 305 consecutive pregnant women who had been referred to our hospital for antenatal care. Of them, 117 self-reported alcohol ingestion in the first trimester of pregnancy and 188 were abstainers. Total PEth concentration in whole blood was quantified by liquid chromatography-mass spectrometry (LC-MS/MS). Alcohol ingestion was classified according to the United States National Institute on Alcohol Abuse and Alcoholism into light drinkers: ≤ 3 drinks/week, moderate drinkers: 3-7 drinks/week, and heavier drinkers: > 7 drinks/week (a standard drink = 14 g of ethanol). <I>Results.</I> Participants had quantifiable PEth blood levels 3-4 weeks after the last drink. There were 4.8% abstainers who had positive PEth concentrations; all of them reported a positive history of alcohol consumption before conception. PEth blood concentrations were significantly correlated to drinks per occasion (<I>r</I> = 0.44; <I>P</I> < 0.001) and days drinking per week (<I>r</I> = 0.34; <I>P</I> < 0.001). However, almost 74% of participants with ≤ 3 drinks/week of alcohol, and 46% with 3-7 drinks/week, had PEth blood concentrations below the lower limit of quantification (LLOQ). The area under the curve (AUC) generated by a receiver operation characteristic curve (ROC) analysis increased as the cutoff value of PEth blood concentration increased. However, the cutoff values were below or close to the LLOQ. <I>Conclusions:</I> Our study presents a formal characterization of PEth blood concentrations for screening alcohol ingestion in first-trimester pregnant women. However, caution is recommended for overrepresenting either negative or positive results.</P>