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RISS 인기검색어
- 검색키워드
- 저자 : Hiroko Kitamura (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
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A 4-Year Follow-up Cohort Study of the Respiratory Functions in Toner-handling Workers
Yanagi, Nobuaki,Kitamura, Hiroko,Mizuno, Mitsuhito,Hata, Koichi,Uchiyama, Tetsuro,Kuga, Hiroaki,Matsushita, Tetsuhiro,Kurosaki, Shizuka,Uehara, Masamichi,Ogami, Akira,Higashi, Toshiaki Occupational Safety and Health Research Institute 2014 Safety and health at work Vol.5 No.4
Background: Focusing on the respiratory function for health effect indices, we conducted a cross-sectional study on workers who did and did not handle toner to compare the longitudinal changes. Methods: Among 116 individuals who worked for a Japanese business equipment manufacturer and participated in the study, the analysis included 69 male workers who we were able to follow up for 4 years. We categorized the 40 workers engaged in toner-handling work as the exposed group and the 29 workers not engaged in these tasks as the referent group, and compared their respiratory function test results: peak expiratory flow rate (PEFR), vital capacity (VC), predicted vital capacity (%VC), forced expiratory volume in 1 second ($FEV_1$), and forced expiratory volume in 1 second as a percent of forced vital capacity ($FEV_1%$). Results: The cross-sectional study of the respiratory function test results at the baseline and at the $5^{th}$ year showed no statistically significant differences in PEFR, VC, %VC, $FEV_1$, and $FEV_1%$ between the exposed and referent workers. Also, respiratory function time-course for 4 years was calculated and compared between the groups. No statistically significant differences were shown. Conclusion: Our study does not suggest any toner exposure effects on respiratory function. However, the number of subjects was small in our study; studies of larger populations will be desired in the future.
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A 4-Year Follow-up Cohort Study of the Respiratory Functions in Toner-handling Workers
Nobuaki Yanagi,Hiroko Kitamura,Mitsuhito Mizuno,Koichi Hata,Tetsuro Uchiyama,Hiroaki Kuga,Tetsuhiro Matsushita,Shizuka Kurosaki,Masamichi Uehara,,Akira Ogami,Toshiaki Higashi 한국산업안전보건공단 산업안전보건연구원 2014 Safety and health at work Vol.5 No.4
Background: Focusing on the respiratory function for health effect indices, we conducted a crosssectionalstudy on workers who did and did not handle toner to compare the longitudinal changes. Methods: Among 116 individuals who worked for a Japanese business equipment manufacturer andparticipated in the study, the analysis included 69 male workers who we were able to follow up for 4years. We categorized the 40 workers engaged in toner-handling work as the exposed group and the 29workers not engaged in these tasks as the referent group, and compared their respiratory function testresults: peak expiratory flow rate (PEFR), vital capacity (VC), predicted vital capacity (%VC), forcedexpiratory volume in 1 second (FEV1), and forced expiratory volume in 1 second as a percent of forcedvital capacity (FEV1%). Results: The cross-sectional study of the respiratory function test results at the baseline and at the 5thyear showed no statistically significant differences in PEFR, VC, %VC, FEV1, and FEV1% between theexposed and referent workers. Also, respiratory function time-course for 4 years was calculated andcompared between the groups. No statistically significant differences were shown. Conclusion: Our study does not suggest any toner exposure effects on respiratory function. However, thenumber of subjects was small in our study; studies of larger populations will be desired in the future
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Risk Factor Analysis for C5 Palsy after Double-Door Laminoplasty for Cervical Spondylotic Myelopathy
Satoshi Baba,Ko Ikuta,Hiroko Ikeuchi,Makoto Shiraki,Norihiro Komiya,Takahiro Kitamura,Hideyuki Senba,Satoshi Shidahara 대한척추외과학회 2016 Asian Spine Journal Vol.10 No.2
Study Design: A retrospective comparative study. Purpose: To clarify the risk factors related to the development of postoperative C5 palsy through radiological studies after cervical double-door laminoplasty (DDL). Overview of Literature: Although postoperative C5 palsy is generally considered to be the result of damage to the nerve root or segmental spinal cord, the associated pathology remains controversial. Methods: A consecutive case series of 47 patients with cervical spondylotic myelopathy treated by DDL at our institution between April 2008 and April 2015 were reviewed. Postoperative C5 palsy occurred in 5 of 47 cases after DDL. We investigated 9 radiologic factors that have been reported to be risk factors for C5 palsy in various studies, and statistically examined these between the two groups of palsy and the non-palsy patients. Results: We found a significant difference between patients with and without postoperative C5 palsy with regards to the posterior shift of spinal cord at C4/5 (p =0.008). The logistic regression analyses revealed posterior shift of the spinal cord at C4/5 (odds ratio, 12.066; p =0.029; 95% confidence interval, 1.295–112.378). For the other radiologic factors, there were no statistically significant differences between the two groups. Conclusions: In the present study, we showed a significant difference in the posterior shift of the spinal cord at C4/5 between the palsy and the non-palsy groups, indicating that the “tethering phenomenon” was likely a greater risk factor for postoperative C5 palsy.
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Clinical Application of Marrow Mesenchymal Stem Cells for Hard Tissue Repair
Hajime Ohgushi,Shigeyuki Kitamura,Noriko Kotobuki,Motohiro Hirose,Hiroko Machida,Kaori Muraki,Yoshinori Takakura 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.SUP
Human marrow mesenchymal stem cells were cultured in a medium containing glycerophosphate, ascorbic acid, and dexamethasone (Dex) on alumina ceramic discs and on tissue culture polystyrene (TCPS) dishes. Cell proliferation followed by osteogenic differentiation was observed to be equal on both culture substrata. The differentiation resulted in the appearance of bone-forming osteoblasts, which fabricated mineralized matrices on these substrata. Stem cells kept at 4℃ for 24 h outside a CO2 incubator maintained a viability level of more than 90%. The regenerative cultured bone outside the incubator also maintained high alkaline phosphatase activity for several hours. These results verified that cultured bone fabricated at a cell processing center can be transported to distant hospitals for use in hard tissue repair. To date, the tissue engineered cultured bone formed on alumina ceramics in this environment have already been used in clinical situations, such as total ceramic ankle replacements.
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