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THE POPULARITY OF ONLINE CONTENTS
Hikaru Yamamoto,Naohiro Matsumura 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.5
In this paper, we explore the popularity of contents at social curation sites. More specifically, we evaluate an article’s popularity at a given point in time and enduring popularity. The results of analyses demonstrate that the amount of content in an article and the initial page views positively affect the page’s popularity. However, an excess amount of content has a negative effect on outbound traffic. Finally, we find that a within-site bookmark prolongs the life of an article.
Hikaru Yamamoto 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07
This study focuses on resale behavior in online consumer-to-consumer market platforms and examines the factors that promote and hinder the resale behavior of sellers. The evidence from the experiment suggests the negative effect of emotional attachment on resale intention and the moderating effect of resale possibilities.
THE POPULARITY OF ONLINE CONTENTS
Hikaru Yamamoto,Naohiro Matsumura 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.7
In this paper, we explore the popularity of contents at social curation sites. More specifically, we evaluate an article’s popularity at a given point in time and enduring popularity. The results of analyses demonstrate that the amount of content in an article and the initial page views positively affect the page’s popularity. However, an excess amount of content has a negative effect on outbound traffic. Finally, we find that a within-site bookmark prolongs the life of an article.
Role of Gap Junctions in the Endothelium-Dependent Hyperpolarization of Vascular Smooth Muscle Cells
Yoshimichi Yamamoto,Megan F. Klemm,Hikaru Hashitani,Richard J. Lang,Tsuyoshi Soji.,Hikaru Suzuki 대한생리학회-대한약리학회 2001 The Korean Journal of Physiology & Pharmacology Vol.5 No.1
<P> Hyperpolarization of arterial smooth muscle by acetylcholine is considered to be produced by the release of an unidentified chemical substance, an endothelium-derived hyperpolarizing factor (EDHF). Several chemicals have been proposed as the candidate for EDHF. However, none of them fulfil completely the nature and property of EDHF. Ultrastructural observation with electron microscope reveals that in some arteries, gap junctions are formed between endothelial and smooth muscle cells. In small arterioles, injection of gap junction permeable dyes into an endothelial cell results in a distribution of the dye to surrounding cells including smooth muscle cells. These observations allow the speculation that myoendothelial gap junctions may have a functional significance. Simultaneous measurement of the electrical responses in both endothelial and smooth muscle cells using the double patch clamp method demonstrates that these two cell types are indeed electrically coupled, indicating that they behave as a functional syncytium. The EDHF-induced hyperpolarization is produced by an activation of Ca<SUP>2</SUP>-sensitive K<SUP></SUP>-channels that are inhibited by charybdotoxin and apamin. Agonists that release EDHF increase [Ca<SUP>2</SUP>]<SUB>i</SUB> in endothelial cells but not in smooth muscle cells. Inhibition of gap junctions with chemical agents abolishes the agonist- induced hyperpolarization in smooth muscle cells but not in endothelial cells. All these observations can be explained if EDHF is an electrotonic signal propagating from endothelium to smooth muscle cells through gap junctions.
Takayuki Takahashi,Hikaru Matsuoka,Rieko Sakurai,Jun Akatsuka,Yusuke Kobayashi,Masaru Nakamura,Takashi Iwata,Kouji Banno,Motomichi Matsuzaki,Jun Takayama,Daisuke Aoki,Yoichiro Yamamoto,Gen Tamiya 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.5
Objective: Human papillomavirus subtypes are predictive indicators of cervical intraepithelial neoplasia (CIN) progression. While colposcopy is also an essential part of cervical cancer prevention, its accuracy and reproducibility are limited because of subjective evaluation. This study aimed to develop an artificial intelligence (AI) algorithm that can accurately detect the optimal lesion associated with prognosis using colposcopic images of CIN2 patients by utilizing objective AI diagnosis. Methods: We identified colposcopic findings associated with the prognosis of patients with CIN2. We developed a convolutional neural network that can automatically detect the rate of high-grade lesions in the uterovaginal area in 12 segments. We finally evaluated the detection accuracy of our AI algorithm compared with the scores by multiple gynecologic oncologists. Results: High-grade lesion occupancy in the uterovaginal area detected by senior colposcopists was significantly correlated with the prognosis of patients with CIN2. The detection rate for high-grade lesions in 12 segments of the uterovaginal area by the AI system was 62.1% for recall, and the overall correct response rate was 89.7%. Moreover, the percentage of high-grade lesions detected by the AI system was significantly correlated with the rate detected by multiple gynecologic senior oncologists (r=0.61). Conclusion: Our novel AI algorithm can accurately determine high-grade lesions associated with prognosis on colposcopic images, and these results provide an insight into the additional utility of colposcopy for the management of patients with CIN2.