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      • KCI등재

        Prediction of Marital Satisfaction Based on Emotional Intelligence in Postmenopausal Women

        ( Mohammad Heidari ),( Sara Shahbazi ),( Mansour Ghafourifard ),( Rahim Ali Sheikhi ) 대한폐경학회 2017 대한폐경학회지 Vol.23 No.3

        Objectives: This study was coperinducted with the aim of prediction of marital satisfaction based on emotional intelligence for postmenopausal women. Methods: This cross-sectional study was the descriptive-correlation and with a sample size of 134 people to predict marital satisfaction based on emotional intelligence for postmenopausal women was conducted in the Borujen city. The subjects were selected by convenience sampling. Data collection tools included an emotional intelligence questionnaire (Bar-on) and Enrich marital satisfaction questionnaire. Results: The results of this study showed a significant positive relationship between marital satisfaction and emotional intelligence (P < 0.05, r = 0.25). Also, regression analysis showed that emotional intelligence (β = 0.31) can predict positively and significantly marital satisfaction. Conclusions: Due to the positive relationship between emotional intelligence and marital satisfaction, adequacy of emotional intelligence is improved as important structural in marital satisfaction. So it seems that can with measuring emotional intelligence in reinforced marital satisfaction during menopause, done appropriate action. (J Menopausal Med 2017;23:196-201)

      • KCI등재

        Comparison of mean platelet volume levels in coronary artery ectasia and healthy people: systematic review and meta-analysis

        Reza Heidary Moghadam,Afshar Shahmohammadi,Nader Asgari,Koorosh Azizi,Sahar Mehr Mansour,Mohammad Roozbahani 대한혈액학회 2018 Blood Research Vol.53 No.4

        Coronary artery ectasia (CAE) is defined as the dilation of a segment of a coronary vessel to at least 1.5 times the diameter of its normal adjacent segment. Mean platelet volume (MPV) plays a role in acute coronary syndromes, with high MPV correlating to poor prog-nosis for acute thrombotic events and CAE. Several studies investigated the relationship between MPV and CAE, resulting in conflicting results. These results led us to systemati-cally review all studies investigating the relationship between MPV and ectatic heart dis-eases by performing a meta-analysis study in order to report a unified result. This meta-analysis study investigated all case-control articles examining the relationship be-tween MPV and CAE. All studies in the following databases published until January 31, 2018, were investigated: Science Direct, Scopus, PubMed, Google Scholar, and Web of Science. Following a quality control evaluation, 14 articles, all of which were published following studies performed in Turkey from 2007 to 2016, met the criteria for study inclusion. After pooling the results from all of the articles, a total standardized mean differ-ence (SMD) value of 0.584 (95% CI, 0.219, 0.95) was obtained using the D+L pooled SMD, indicating a significant difference (P=0.002) between the two groups, with higher MPV values in ectatic patients when comparing to healthy individuals. Therefore, in-creased MPV levels were significantly related to CAE, suggesting that platelets, with their inflammatory and thrombotic activities, play a role in this disease. Therefore, anti-platelet and anti-inflammatory therapies may be effective in treating CAE.

      • KCI등재

        Gene cloning, bacterial expression, and purification of calreticulin from Anopheles stephensi (AsCRT)

        Nahid BORHANI,Mansour HEIDARI,Hamid R. BASSERI 한국곤충학회 2012 Entomological Research Vol.42 No.1

        During the invasion of Plasmodium ookinetes to the mosquito midgut epithelium, several proteins or glycoproteins are involved. Recent study has shown that the calreticulin (CRT) of the midgut from Anopheles albimanus can bind to the protein receptor Pvs25 on surface of Plasmodium vivax ookinetes. Thus, in order to get more insight into the potential roles of Anopheles stephensi calreticulin (AsCRT) in the midgut, we amplified and cloned the full-length of calreticulin coding sequence from Anopheles stephensi. The AsCRT consists of 1221 bp nucleic acids with one open reading frame (ORF) encoding 406 amino acids and an apparent molecular weight around 46 KDa. Subsequently, the recombinant calreticulin as Glutathione S-transferase (GST) fusion in pGEX -6p-1 expression vector (GST-AsCRT) was produced in the prokaryotic system under optimum conditions. GST-AsCRT fusion protein has a molecular weight around 73 KDa. The recombinant protein was detected byWestern blotting using a rabbit anti-GST polyclonal antibody. Here, we report via single protein purification procedure using MagneGST beads, 25 mg of the recombinant protein was obtained per liter of bacterial culture. This is the first report describing the heterologous expression of Anopheles stephensi calreticulin in the prokaryotic system. The production of this recombinant protein will now allow us to further investigate AsCRT molecular protein analyses, characterization of physiochemical properties, as well as interaction between calreticulin and plasmodium protein surface.

      • Mitochondrial D-Loop Polymorphism and Microsatellite Instability in Prostate Cancer and Benign Hyperplasia Patients

        Ashtiani, Zahra Ousati,Heidari, Mansour,Hasheminasab, Sayed-Mohammad,Ayati, Mohsen,Rakhshani, Naser Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

        In this study mitochondrial D-Loop variations in Iranian prostate cancer and benign prostatic hyperplasia (BPH) patients were investigated. Tumour samples and corresponding non-cancerous prostate tissue from 40 prostate cancer patients and 40 age-matched BPH patients were collected. The entire mtD-loop region (16024-576) was amplified using the PCR method and products were gel-purified and subjected to direct nucleotide sequencing. A total of 129 variations were found, the most frequent being 263A${\rightarrow}$G and 310T${\rightarrow}$C among both BPH and prostate cancer patients. Variation of 309 C${\rightarrow}$T was significantly more frequent in prostate cancer patients (P value<0.05). Four novel variations were observed on comparison with the MITOMAP database. Novel variations were np16154delT, np366G${\rightarrow}$A, np389G${\rightarrow}$A and 56insT. There was no correspondence between the different variations and the age of subjects. Considering that D-loop variations were frequent in both BPH and prostate cancer patients in our study, the fact that both groups had high average age can be a possible contributing factor. D-loop polymorphisms and microsatellite instability can influence cell physiology and result in a benign or malignant phenotype. Significantly higher frequency of 309 C${\rightarrow}$T variation in cancer patients is a notable finding and must be a focus of attention in future studies.

      • KCI등재

        Horizontal and vertical crossover of sine cosine algorithm with quick moves for optimization and feature selection

        Hu Hanyu,Shan Weifeng,Tang Yixiang,Heidari Ali Asghar,Chen Huiling,Liu Haijun,Wang Maofa,Escorcia-Gutierrez José,Mansour Romany F,Chen Jun 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.6

        The sine cosine algorithm (SCA) is a metaheuristic algorithm proposed in recent years that does not resort to nature-related metaphors but explores and exploits the search space with the help of two simple mathematical functions of sine and cosine. SCA has fewer parameters and a simple structure and is widely used in various fields. However, it tends to fall into local optimality because it does not have a well-balanced exploitation and exploration phase. Therefore, in this paper, a new, improved SCA algorithm (QCSCA) is proposed to improve the performance of the algorithm by introducing a quick move mechanism and a crisscross mechanism to SCA and adaptively improving one of the parameters. To verify the effectiveness of QCSCA, comparison experiments with some conventional metaheuristic algorithms, advanced metaheuristic algorithms, and SCA variants are conducted on IEEE CEC2017 and CEC2013. The experimental results show a significant improvement in the convergence speed and the ability to jump out of the local optimum of the QCSCA. The scalability of the algorithm is verified in the benchmark function. In addition, QCSCA is applied to 14 real-world datasets from the UCI machine learning database for selecting a subset of near-optimal features, and the experimental results show that QCSCA is still very competitive in feature selection (FS) compared to similar algorithms. Our experimental results and analysis show that QCSCA is an effective method for solving global optimization problems and FS problems.

      • KCI등재

        The relationship between common mutations in CFTR, AR genes, Y chromosome microdeletions and karyotyping abnormalities with very severe oligozoospermia in Iranian men

        Jafari Leyla,Safinejad Kyumars,Nasiri Mahboobeh,Heidari Mansour,Houshmand Massoud 한국유전학회 2023 Genes & Genomics Vol.45 No.4

        Background Male infertility due to very severe oligozoospermia has been associated with some genetic risk factors. Objective To investigate the distribution of the mutations in the CFTR gene, the CAG-repeat expansion of the AR gene, also Y chromosome microdeletions and karyotyping abnormalities in very severe oligozoospermia patients. Methods In the present case–control study, 200 patients and 200 fertile males were enrolled. All patients and control group were karyotyped. Microdeletions were evaluated using multiplex PCR. Five common CFTR mutations were genotyped using the ARMS-PCR technique. The CAG-repeat expansion in the AR gene was evaluated for each individual using sequencing. Results Overall 4% of cases shows a numerical and structural abnormality. 7.5% of patients had a deletion in one of the AZF regions on Yq, and 3.5% had a deletion in two regions. F508del was the most common (4.5%) CFTR gene mutation; G542X, and W1282X were detected with 1.5% and 1% respectively. One patient was found to have AZFa microdeletion and F508del in heterozygote form; one patient had AZFb microdeletion with F508del. F508del was seen as compound heterozygous with G542X in one patient and with W1282X in the other patient. The difference in the mean of the CAG-repeats in the AR gene in patients and control groups was statistically significant (P = 0.04). Conclusion Our study shows the genetic mutations in men with severe oligozoospermia and given the possibility of transmission of these disorders to the next generation by fertilization, counseling and genetic testing are suggested for these couples before considering ICSI.

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