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석면함유 슬레이트 지붕 물받이 퇴적물 중 석면 섬유 함유율
임지현,한솔민,김현석,신유민,박시은,허정윤,김민영,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2
This study attempted to determine the degree of asbestos release from the aging slate roof by comparing the asbestos content in the slate roof rain gutter with a colored steel plate (tin plate) over the slate roof. Four slate roof houses located in Haengmok-ri, Asan-si, Chungcheongnam-do, and one house constructed with a colored steel plate on the slate roof were selected to collect the sediment of the roof rain gutter. The asbestos fiber content was calculated by a point counting method using a polarization microscope after pretreatment with conversion treatment and hydrochloric acid treatment. The average asbestos content of the four slate roof rain gutter were 1.89%. However, asbestos was not detected in the Slate covering roof rain gutter, which were constructed on the slate roof. Asbestos fiber content was the highest at 2.89% in the slate roof rain gutter installed in 1976, followed by 2.44% in 1953. From the above results, it is necessary to minimize secondary damage as asbestos fibers released from slate roof houses to the surrounding atmosphere or leaked from slate roofs as rainwater may cause soil pollution and seriously affect residents' health. Although covering with colored steel plates (tin plates) has been shown to prevent the leakage of asbestos fibers to some extent, it is believed that a policy alternative to remove the slate roof as soon as possible is needed to solve the fundamental problem.
사무직 근로자의 수면의 질 및 직무스트레스와 우울과의 관련성
강미나,강수영,권수정,김현주,배재원,이보연,이예진,임의롬,정다영,조한솔 이화여자대학교 간호과학대학 2013 이화간호학회지 Vol.- No.47
Purpose: The purpose of this study was to understand the degree of depression, sleep quality, job stress and their association among office workers. Method: A self-administered questionnaire was distributed to 147 workers employed in 5 big enterprises, and 5 small and medium enterprises from October 21 to November 21, 2012. The questionnaires included socio-demographic and health-related characteristics, job-related characteristics, sleep quality, job stress (KOSS) and depression (CES-D). Result: Among all subjects, 23.1% was in the depression group (21 points and over in the CES-D score). Depressive level was positively correlated with job stress and quality of sleep. The adjusted odd ratio for the effects of sleep quality and job stress on depression significantly increased in the depression group compared to that of the normal group. Multiple regression analysis revealed that the following factors of influence had combined explanatory powers on depression: BMI, life satisfaction, quality of sleep, and job stress. Conclusion: The study revealed that complicated influences were exerted on the level of depression by variable factors, as well as socio-demographic characteristics, health-related characteristics, quality of sleep, and job stress. Specifically, the level of depression was influenced by the quality of sleep and job stress.
Kim, Han Sol,Park, Jin Bae,Joo, Young Hoon The Korean Institute of Electrical Engineers 2017 Journal of Electrical Engineering & Technology Vol.12 No.6
In this paper, a linear matrix inequality-based sampled-data fuzzy observer design method is proposed based on the exact discretization approach. In the proposed design technique, a numerically relaxed observer design condition is obtained by using the discrete-time fuzzy Lyapunov function. Unlike the existing studies, the designed observer is robust to the uncertain premise variable because the fuzzy observer is designed under the imperfect premise matching condition, in which the membership functions of the system and observer are mismatched. In addition, we apply the proposed method to the state estimation problem of the attitude and heading reference system (AHRS). To do this, we derive a Takagi-Sugeno fuzzy model for the AHRS system, and validate the proposed method through the hardware experiment.
Han Sol Kim,Jin Bae Park,Young Hoon Joo 대한전기학회 2017 Journal of Electrical Engineering & Technology Vol.12 No.6
In this paper, a linear matrix inequality-based sampled-data fuzzy observer design method is proposed based on the exact discretization approach. In the proposed design technique, a numerically relaxed observer design condition is obtained by using the discrete-time fuzzy Lyapunov function. Unlike the existing studies, the designed observer is robust to the uncertain premise variable because the fuzzy observer is designed under the imperfect premise matching condition, in which the membership functions of the system and observer are mismatched. In addition, we apply the proposed method to the state estimation problem of the attitude and heading reference system (AHRS). To do this, we derive a Takagi-Sugeno fuzzy model for the AHRS system, and validate the proposed method through the hardware experiment.
Kim, Han Sol,Li, Hongliang,Kim, Hye Won,Shin, Sung Eun,Seo, Mi Seon,An, Jin Ryeol,Ha, Kwon-Soo,Han, Eun-Taek,Hong, Seok-Ho,Choi, Il-Whan,Choi, Grace,Lee, Dae-sung,Park, Won Sun The Korean Society of Pharmacology 2017 The Korean Journal of Physiology & Pharmacology Vol.21 No.4
We investigated the inhibitory effect of escitalopram, a selective serotonin reuptake inhibitor (SSRI), on voltage-dependent $K^+$ (Kv) channels in freshly separated from rabbit coronary arterial smooth muscle cells. The application of escitalopram rapidly inhibited vascular Kv channels. Kv currents were progressively inhibited by an increase in the concentrations of escitalopram, suggesting that escitalopram inhibited vascular Kv currents in a concentration-dependent manner. The $IC_{50}$ value and Hill coefficient for escitalopram-induced inhibition of Kv channels were $9.54{\pm}1.33{\mu}M$ and $0.75{\pm}0.10$, respectively. Addition of escitalopram did not alter the steady-state activation and inactivation curves, suggesting that the voltage sensors of the channels were not affected. Pretreatment with inhibitors of Kv1.5 and/or Kv2.1 did not affect the inhibitory action of escitalopram on vascular Kv channels. From these results, we concluded that escitalopram decreased the vascular Kv current in a concentration-dependent manner, independent of serotonin reuptake inhibition.
Kim, Ki Eun,Heo, Ju Sun,Han, Sol,Kwon, Seul-Ki,Kim, Soo-Yeon,Kim, Jung Hyun,Baek, Kwang-Hyun,Sheen, Youn Ho Elsevier 2018 Clinica chimica acta Vol.486 No.-
<P><B>Abstract</B></P> <P><B>Background</B></P> <P>We assessed the association of insulin resistance as indicated by the homeostatic model assessment of insulin resistance (HOMA-IR) with inflammatory molecules, lipopolysaccharide-binding protein (LBP), high sensitivity C-reactive protein (hs-CRP), Tumor necrosis factor-α (TNF-α), and Interleukin-6 (IL-6) in urban young adolescents.</P> <P><B>Methods</B></P> <P>Seventy-six adolescents (36 subjects with HOMA-IR ≥ 2.6 and 40 subjects with HOMA-IR < 2.6) were included in the study. We assessed anthropometric and laboratory measures, such as BMI, blood pressure, insulin sensitivity, liver enzymes, and lipid profiles along with the aforementioned inflammatory biomarkers. The diagnostic accuracy of LBP, hs-CRP, TNF-α, and IL-6 for insulin resistance was evaluated by using the receiver operating characteristic (ROC) curve analysis.</P> <P><B>Results</B></P> <P>The mean age of the study subjects was 12.0 [12.0–13.0] y. Circulating LBP plasma concentration and hs-CRP were significantly increased in subjects with HOMA-IR ≥ 2.6 when compared with those with HOMA-IR < 2.6 (<I>P</I> < .0001). There was no difference in TNF-α or IL-6 concentrations between groups. Comparisons based on the area under the ROC curve for LBP, hs-CRP, TNF-α, and IL-6 with regard to insulin resistance (HOMA-IR ≥ 2.6) were 0.8384 (95% CI: 0.7380 to 0.9388), 0.7907 (95% CI: 0.6701 to 0.9113), 0.6207 (95% CI: 0.4770 to 0.7643), and 0.5763 (95% CI: 0.4285 to 0.7241), respectively.</P> <P><B>Conclusions</B></P> <P>Among LBP, hs-CRP, TNF-α, and IL-6, plasma LBP has the greatest diagnostic accuracy for insulin resistance in young adolescents. Prospective studies are warranted to delineate the value of LBP in the prediction of insulin resistance.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Plasma LBP is increased in young adolescents with insulin resistance and has the greatest diagnostic accuracy for insulin resistance. </LI> </UL> </P>