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- 저자 : Hamed Emami (검색결과 2 건)
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Hooman Abedi,Massoud Emamy,Jafar Rassizadehghani,Hamed Mirzadeh 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.5
The effects of cerium-based rare earth (RE) addition and hot deformation via extrusion on the microstructure and mechanicalproperties of Mg-0.5Zn-0.5Zr alloy were studied. It was found that RE addition could effectively refine the as-cast microstructureup to 2 wt% RE with a notable grain refining effect up to 1 wt% RE. High RE additions resulted in a less effectivegrain refinement and the appearance of coarse dendritic microstructure. While the as-cast strength and ductility wereenhanced by increasing RE content up to 1 wt% due to grain refinement, alloys with high RE content faced a remarkable dropin total elongation and also showed lower ultimate tensile strength (UTS) values, which was related to the interconnectedintergranular brittle intermetallics (Mg12RE) with high volume fractions. For the extruded alloy with 1 wt% RE, besidesthe fragmentation and dispersion of intermetallics, a remarkable grain refinement due to the recrystallization processes wasobserved. Accordingly, the UTS of 415 MPa, total elongation of 17% and tensile toughness of 65.9 MJ/m3 were obtained afterextrusion, which are quite superior to the corresponding values of 210 MPa, 12% and 22.1 MJ/m3 for the as-cast counterpart,respectively. Regardless of the processing condition, the grain size effect was found to be the dominant factor in determiningthe yield stress (Hall–Petch law), where the deviation of this trend due to the presence of hard Mg12REphase was discussed.
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Daniel Addison,Patrick R. Lawler,Hamed Emami,Sumbal A. Janjua,,Pedro V. Staziaki,Travis R. Hallett,Orla Hennessy,Hang Lee,Bálint Szilveszter,Michael Lu,Negar Mousavi,Matthew G. Nayor,Francesca N. Dell 대한뇌졸중학회 2018 Journal of stroke Vol.20 No.1
Background and Purpose Interventions to reduce the risk for cerebrovascular events (CVE; stroke and transient ischemic attack [TIA]) after radiotherapy (RT) for head and neck cancer (HNCA) are needed. Among broad populations, statins reduce CVEs; however, whether statins reduce CVEs after RT for HNCA is unclear. Therefore, we aimed to test whether incidental statin use at the time of RT is associated with a lower rate of CVEs after RT for HNCA. Methods From an institutional database we identified all consecutive subjects treated with neck RT from 2002 to 2012 for HNCA. Data collection and event adjudication was performed by blinded teams. The primary outcome was a composite of ischemic stroke and TIA. The secondary outcome was ischemic stroke. The association between statin use and events was determined using Cox proportional hazard models after adjustment for traditional and RT-specific risk factors. Results The final cohort consisted of 1,011 patients (59±13 years, 30% female, 44% hypertension) with 288 (28%) on statins. Over a median follow-up of 3.4 years (interquartile range, 0.1 to 14) there were 102 CVEs (89 ischemic strokes and 13 TIAs) with 17 in statin users versus 85 in nonstatins users. In a multivariable model containing known predictors of CVE, statins were associated with a reduction in the combination of stroke and TIA (hazard ratio [HR], 0.4; 95% confidence interval [CI], 0.2 to 0.8; P=0.01) and ischemic stroke alone (HR, 0.4; 95% CI, 0.2 to 0.8; P=0.01). Conclusions Incidental statin use at the time of RT for HNCA is associated with a lower risk of stroke or TIA.
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