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        Effect of Co Doping on the Elastocaloric Effect of Ni-Mn-Ga-Co Alloy

        Haixu Qin,Youping Zheng,Liu Yang,Sibo Sun,Zhiyong Gao 한국자기학회 2023 Journal of Magnetics Vol.28 No.3

        Large latent heat is produced in the stress-induced martensitic phase transition process of Ni-Mn-Ca-based materials, i.e., elastocaloric effect. That makes such materials show tremendous potential for solid-state refrigeration which is identified as one of the most promising non-vapor-compression cooling devices. However, the still low refrigeration ability of these materials restricts further commercially promoting of solid-state refrigeration. In this work, we adjusted the Co content to regulate the elastocaloric effect for the Ni51.5Mn25Ga23Co0.5. According to the results, the transformation strain and ratio of loading stress/transformation temperature (dσ/ dT) were increased by replacing the Ni atoms with a little more Co, leading to an improvement of the stressinduced transformation entropy-change ΔSσ. As a result, a huge ΔSσ of 45.0 JKg-1K-1 is achieved in Ni50Mn25- Ga23Co1 alloy.

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        Establishment and evaluation of a murine anb3-integrinexpressing cell line with increased susceptibility to Foot-and-mouth disease virus

        Wei Zhang,Kaiqi Lian,Fan Yang,Yang Yang,Zhijian Zhu,Zixiang Zhu,Weijun Cao,Ruoqing Mao,Ye Jin,Jijun He,Jianhong Guo,Xiangtao Liu,Haixue Zheng 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.3

        Integrin anb3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and rolesof anb3 integrin, a stable CHO-677 cell line expressing the murine anb3 heterodimer (designated as “CHO-677-manb3” cells) wasestablished using a highly efficient lentiviral-mediated gene transfer technique. Integrin subunits an and b3 were detected at the gene andprotein levels by polymerase chain reaction (PCR) and indirect immunofluorescent assay (IFA), respectively, in the CHO-677-manb3 cellline at the 20th passage, implying that these genes were successfully introduced into the CHO-677 cells and expressed stably. A plaque-formingassay, 50% tissue culture infective dose (TCID50), real-time quantitative reverse transcription-PCR, and IFA were used to detect the replicationlevels of Foot-and-mouth disease virus (FMDV) in the CHO-677-manb3 cell line. After infection with FMDV/O/ZK/93, the cell line showeda significant increase in viral RNA and protein compared with CHO-677 cells. These findings suggest that we successfully established a stableanb3-receptor-expressing cell line with increased susceptibility to FMDV. This cell line will be very useful for further investigation of anb3integrin, and as a cell model for FMDV research.

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