Research Articles : Geographic Genetic Contour of A Leaf Beetle, Chrysolina aurichalcea (Coleoptera: Chysomelidae), on the Basis of Mitochondrial COI Gene and Nuclear ITS2 Sequences

( Joong Won Park ),( Sun Young Park ),( Ah Rha Wang ),( Min Jee Kim ),( Hae Chul Park1 ),( Iksoo Kim ) 한국잠사학회 2011 International Journal of Industrial Entomology Vol.23 No.1

The leaf beetle, Chrysolina aurichalcea (Coleoptera: Chysomelidae), is a pest damaging plants of Compositae. In order to understand the genetic diversity and geographic variation we sequenced a portion of mitochondrial COI gene (658 bp) and complete nuclear internal transcribed spacer 2 (ITS2) of the species collected from seven Korean localities. A total of 17 haplotypes (CACOI01~CACOI17), with the maximum sequence divergence of 3.04% (20 bp) were obtained from COI gene sequence, whereas 16 sequence types (ITS2CA01~ITS2CA16), with the maximum sequence divergence of 2.013% (9 bp) were obtained from ITS2, indicating substantially larger sequence divergence in COI gene sequence. Phylogenetically, the COI gene provided two haplotype groups with a high nodal support (≥87%), whereas ITS2 provided only one sequence type group with a high nodal support (≥92%). The result of COI gene sequence may suggest the presence of historical biogeographic barriers that bolstered genetic subdivision in the species. Different grouping pattern between COI gene and ITS2 sequences were interpreted in terms of recent dispersal, reflected in the ITS2 sequence. Finding of unique haplotypes and sequence types only from Beakryeng-Islet population was interpreted as an intact remnant of ancient polymorphism. As more samples are analyzed using further hyper-variable marker, further fruitful inference on the geographic contour of the species might be available.

공급사슬에서 수량할인과 수익공유를 반영한 계약

박세호(Se Ho Park),이영해(Young Hae Lee),조동원(Dong Won Cho) 한국SCM학회 2012 한국SCM학회지 Vol.12 No.2

One of the most important reasons in pursuit of supply chain management is to prevent sub-optimization caused by decentralized decision making over the various entities. As supply chain coordination approach to overcome such a setting, contract mechanisms have frequently been used. However, a coordinated supply chain might fail to provide additional profit to one of the players. In result, it is necessary that a contract mechanism is designed to achieve the same profit in a centralized situation (coordination) and to improve the benefit of all the supply chain players (winwin). In this paper, we address supply chain contract based on revenue sharing and quantity discount considering price and service level. We show that the trade parameters among different entities in the supply chain contract can be chosen to achieve coordination and a win-win outcome.

두 마리의 면역매개성 혈고판감소증 개에서의 MMF를 이용한 치료

손혜진,박형진,서경원,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

Two dogs (case 1: 4-years-old female Dachshund, case 2: 1-years-old male maltese) were reffered with petechia. Result of blood analysis and coagulation test reveled immune-mediated thrombocytopenia in all dogs. Treatment with MMF for them, case 1 present steroid-induced hepatopathy, case 2 present anemia, so treated with Human IgG and blood transfusion. 3(case 1) or 2(case 2) months after initial treatment, clinical features were improved, and continuous monitoring is needed.

도장부스가 2개인 자동차 조립공장의 생산순서계획 작성

박혜규,최원준,강혜영 울산대학교 1998 경영학연구논문집 Vol.5 No.2

The main line of an automotive assembly plant normally consists of a body line, a painting line, and an assembly line. For determining the production sequence, leveling of heavy options is the major concern for body line and assembly line whereas production of bodies with the same color consecutively is more important in case of the painting line. In this paper, we propose an algorithm for generating the production sequence plan for an automotive assembly plant having the dual painting booths. The proposed algorithm turns out very effective in terms of the global performance measure of the assembly plant.

한베이식 언어 설계 및 명령어 처리에 관한 연구

元裕憲,林海喆,朴道淳 弘益大學校 1983 弘大論叢 Vol.15 No.2

This papaer presents the design of programming language, named HAN-BASIC(HANgul BASIC), which is especially devised for the personal computer users who can't even understand English. This language gives the ability of programming with Korean language, permitting English variable names. In order to respond in real time, HAN-BASIC reserved-words is parrsed using hashing and finite automata method.

Rigid Gas Permeable Contact Lens 재료물질에 관한 연구

朴惠正,朴景石,李原鎭 대구산업정보대학 1998 논문집 Vol.12 No.2

To improve the characteristic properties of contact lens materials, the copolymer of HEMA monomer NVP and MAOPTES monomer have been synthesized by the composition ratio of 50:45:5, 50:40:10 and 50:35:15. The copolymer of TMSOEMA monomer with HEMA and NVP have been synthesized as same compositional ratio as MAOPTES. Water content, swelling ratio, contact angle, permeability of oxygen and quantity of adsorptive protein were measured to check properties of copolymers. The experimental result measured for the copolymer containing silicon derivative of low ratio was prefered to be the materials of contact lens which can improve the function, due to the low absorption of protein compound to poly(HEMA) and to the high oxygen permeabilities

「韓國倫理」의 敎育的 價値志向

朴仁熙,宋海永,金元述 경북대학교 1992 논문집 Vol.24 No.-

Since the opening of this country in 1876, we had kept our own cultural orientation and this cultural orientation had been working as principle of our individual and community life. But this orientation became degraded through the colonial policy of Japan and the set-up of military government by U. S. A and U. S. S. R, and also came to be deformed after the division of the country. From these reasons, it follows that modern Korean Ethics must tend to creativly modify the cultural orientation, which we aimed since 1876, and that Korean Ethics must be based on this fact. This is the question at issue and the object of this paper, For the settlement of the question, this paper develops the following details. First, the concept of Korean Ethics is defined on the level of cultural specificity and universality, and the orientation of Korean Ethics is explaned with relation to that of Korean Culture. Second, we had considered the education of Korean Ethics dividing our modern history into the opeining the country, the colonization, the military government of two powers and the post-establishment of two Korea. Third, the value that Korean Ethics must aim is discussed with reference to man, society and nation. In conclusion, it is argued that with the succession of our cultural orientation, Korean Ethics must be established by way of national consensus, and that through the educative efforts it must be interiorized towards the members of our society.

미세혈관 협심증 환자의 임상상 및 지표에 관한 연구

박상호,온영근,김현정,이태훈,길효욱,김현건,박수진,송해정,한대희,방덕원,신원용,이내희,김성구,권영주 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : Microvascular angina or syndrom X is heterogenous and encompasses different pathogenetic entities. Several studies suggest that microvascular angina have good prognosis and occurs predominantly in postmenopausal women. Lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and fibrinogen are the independent risk factor of acute coronary syndrome and are the chief underlying cause of atherosclerosis. We investigated clinical characteristics and markers in patients with microvascular angina. Methods : We studies 23 patients diagnosed with microvascular angina and 16 control group with negative treadmill exercise test and no significant coronary angiogram. We investigated clinical characteristics in patients group and evaluated symptom during a follow-up period of 4.2± 2.5 month. Exercise time in treadmill exercise test was compared between patients and control group. We assessed the level of markers, such as lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and ESR in two groups. Results : There is no difference in age between two groups. Patients group had a tendency to increase in female, hypertension, DM, and smoking history, but there was no statistical significance difference. Exercise duration time was significantly decreased in patients with microvascular angina (p<0,05). Serum lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholestrol, Triglyceride, ESR, Fibrinogen and Homocystein value were no significant difference between microvascular angina and control group. Only CRP was significantly high in patients with microvascular angina (p<0.05). Conclusion : There was no statistical significance difference in age, sex, hypertension, DM and smoking history between two groups but patients group had a tendency to increase the prevalence in hypertension, DM and smoking history, female. Also, Symptom improvement and disappearance in follow-up was presented in 11 patients of 19(57.9%). Exercise tolerance was worse in patients group than control group. CRP value was significantly higher in patients group than control group. There was no statistical significance difference in lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, ESR and Fibrinogen between two groups.

콜레라독소의 피하투여에 의한 생쥐의 림프절 및 비장내 B 및 T 림프구의 분포변화

이원규,박낙진,김종원,허영범,김정혜,안희경 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.2

5-Fluorouracil과 그 유도체를 함유하는 Solid Lipid Nanoparticles 제조와 평가

서혜선,최명신,한규원,박소민,김길수 이화여자대학교 약학연구소 2005 藥學硏究論文集 Vol.- No.16

Solid lipid nanoparticles(SLNs) are particulate systems for parenteral drug administration and have good biocompatibility and stability. SLNs were prepared with lauric acid, as the lipid core. Tween 20 and tween 80 were used as surfactant. 5-fluorouracil and 1-benzoyl-5-fluorouracil were used as model drugs. Drug-loaded SLNs were prepared by the hot homogenization technique in order to evaluate the physical stability, entrapment efficiency of drugs as well as release profile. The particle size of SLNs was 40~600 nm. By increasing speed, the mean particle size of SLfs was decreased. And entrapment efficiency in the case of using 1-Benzoyl-5-fluorouracil was higher than using 5-Fluorouracil. The higher surfactant concentration, the faster release rate at the range of 1.5~2.5%.