천식치료의 현황과 대책

유광하,김미진,김순종 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.13 No.-

Asthma is disease with affect in the almost every coner in the world and it is estimated worldwide we have 300 million people with this disease. The distribution of this disease varying from place to place such that in English speaking country such as USA, Canada, Australia and some part of South America, the prevalence of clinical asthma is more than ten percent. In Asia pacific area, the prevalence is about 2.5%. Several surveys have been done in the last 5 years starting with the AIA so called Asthma In America, followed ALA data, the AIRE data, AIRIAP data, AIJ data was done. The purpose of this survey were to see how well the disease is being controlled. According to the surveys asthma is possessed big burden on health care budget in worldwide. About 25% of patients in Europe, 47% of patients in Japan had urgent visit to local clinics and 10% in Europe and 23% in USA had an emergency room visit in the past year. The percentage of hospitalization ranged form 7% in Europe to 19% in Central and East Europe. Only 5% have what we called good control of asthma according to the GINA criteria. As a result, asthma impact significantly one's life. The goal of asthma treatment is to achieve every asthmatic should feel normal and be free to live their life. For achieving this, practical strategies have to be developed for well understanding about asthma, perception of asthma as a chronic disease, which needs persistent asthma management.

쓰가루 單一品種 果園을 위한 꽃사과 受粉樹 利用에 관한 硏究

沈慶久,河有美,金健澔,朴永洙 成均館大學校 科學技術硏究所 1993 論文集 Vol.44 No.1

Crabapples potentially useful as pollenizers in single-cultivar 'Tsugaru' orchard was evaluated for their flowering times and pollen germination(%). Their efficiency in the setting of fruits following controlled pollinations on 'Tsugaru' at private orchard in Sang ju was also examined. The obtained results are as follows, (1) Flowering times of Malus spp. 'Almey' and Malus spp. `Pioneer X' were from April 30 to May 1 and had the same flowering time of 'Tsugaru'. (2) Pollen germination(%) of crabapples using as pollenizers of 'Tsugaru' was over 90% of Malus spp. 'Almey' and Malus spp. 'Pioneer X' respectively. (3) Percentages of fruit setting in 'Tsugaru' crossed with Malus spp. 'Almey' and with 'Pioneer X' showed 99.3% respectively. (4) There was no statistically significant difference in the fruit skin color, fruit diameter (cm), fruit. height (cm), fruitt index, fruit weight(g), soluble solid(˚BX), acidity(pH), fruit hardness (kg/㎠), and seed numbers of 'Tsugaru' crossed with 'Pioneer X' and 'Almey'. (5) On the bases of flowering times, pollen germination, efficient fruit set, promising of fruit skin solour, and no statistically significant difference in fruit quality, Malus spp. 'Almey' and 'Pioneer X' are promising as pollenizers for single-cultivar 'Tsugaru' orchard.

무궁화 根群 分布에 관한 연구 : 2. 土壤 種類別 實生苗의 根群 分布 2. Root system of seedlings on the soil conditions.

심경구,하유미,김진춘,서병기,강호철 성균관대학교 생명과학자원연구소 1995 生命資源科學硏究 Vol.2 No.1

This study was carried out to examine the characteristics of root system for seedlings of Hibiscus syriacus L. on the different soil conditions as a basic study for the stock of top-root cultivars. The obtained results are summarized as follows; It was significantly different on soil hardness between upland soil with 13 kg f/cm2 until 60 cm depth and waste landfill soil with 5 kg f/cm2 until 5 cm depth. But it was not measured soil hardness under 30 cm of waste landfill soil because of waste base. But soil pH was not different between soil conditions. The root depth of 'SKK 91-3' growing on upland soil was 81.0 cm and it was significantly different as compared with that of 'SKK 91-3' on the waste landfill. In addition, 'SKK 91-3' growing on upland soil had more root weight, root width, root number, main root diameter, and shoot growth than that on the waste landfill. Therefore it was suggested that soil condition affect root growth of seedlings in Hibiscus syriacus L. and then induce top-root system.

미국 및 캐나다 地域에서 栽培, 販賣되고 있는 무궁화 品種에 關한 硏究

沈慶久,河有美,朴永洙,金健澔 成均館大學校 科學技術硏究所 1993 論文集 Vol.44 No.1

This sutdy was carried out to examine the present distribution and status of Hibiscus cultivars by analyzing the US and Canadian market. The obtained results are summerized as follow : 1. At present, a total of 28 cultivars of Hibiscus are on the market. Among these, twenty four are diploids and four are triploids. The hottest cultivars in the market is a triploid `Diana' sold by 21 different companies. It is followed by 'Ardens' and 'Jeanne d'Arc', following `Red Heart', `Blue Bird', 'Woodbridg e', and 'Helene'. 2. As a conservation or display purpose, several cultivars are ketp in three different arboretums in the US. These include 5 cultivars, `Blue Bird', `Celestial Blue', `Collie Mullens', 'Lucy', and `Ruber Plena', in Arnold Arboretum, and one each, 'Variegatus', at the USDA national arboretum and, `Banner' at Morton arboretum in Chicago. 3. The avarage price for triploid cultivars is $6.00 for each seedling. The recently developed cultivars like 'Helene' and 'Minerva' cost $16.00 per seedling possibly due to their plant patent right. Other cultivars produced by cuttings cost $2.00 to $ 3.00 per seedling. 4. In Canada, there are nine cultivars on the market; being diploids and one triploid, `Diana'. 5. As for the distribution of different cultivars by climatic zone, twelve cultivars are being grown in temperate area like Ohio and Iowa. However, many other cultivars are being cultivated in wamer Southern state like Galifornia. Five cultivars are reported to grow in the relatively cool area like Wisconsin and Minnesota. Even in cold area like Canada, 5 cultivars such as `Anemonaeflorus'(2n), `Ardens'(2n), 'Jeanne d'Arc'(2n), and `Luky'(2n), and 'Paeoniflorus'(2n) at Ontario and there is colder than Hamkyung Do in north Korea.

황금배 品種의 單一品種 果園을 위한 콩배 受粉樹 移用에 관한 硏究

沈慶久,河有美,李俊馥,崔勇洵 성균관대학교 생명과학자원연구소 1994 生命資源科學硏究 Vol.1 No.1

Fauriei pear(Pyrus fauriei Nakai) potentially useful as pollenizers in single-cultivar `Hwangkuembae' orchard was evaluated for their flowering times and pollen germination(%). Their efficiency in the setting of fruits following controlled pollinations on 'Hwangkuembae' at Fruit Tree Research Institute in Suwon was also examined. The obtained results are as followes ; (1) Flowering times of SKK 1 was from April 21 and that of them corresponded to that of 'Hwangkuembae'. (2) Pollen germination (%) of SKK 1 using as pollenizer of 'Hwangkuembae' was over 90%. Therefore Based on these factors, folwering times and pollen germination, SKK 1 was found to be promising as pollenizer for single-cultivar 'Hwangkuembae' orchard. (3) Percentage of fruit setting in 'Hwangkuembae' pollinated with Fauriei pear showed 71.9%. And there was no statistically significant difference in the fruit diameter(cm), fruit height(cm), fruit index, fruit weight (g), soluble solid(˚BX), acidity(pH), and fruit hardness (kg/㎠) of 'Hwangkuembae' pollinated with Fauriei pear (4) Percentages of fruit setting in 'Hwangkuembae' pollnated with Fauriei pear corresponding to flowering times of 'Hwangkuembae', was 871.9% and no statistically significant difference in fruit quality. On the bases of flowering times, pollen germination(%), efficient fruit set(%), and no statistically significant difference in fruit quality, Fauriei pear(Pyrus fauriei Nakai) is promising as pollenizers for single-cultivar 'Hwangkuembae' orchard.

揷木用土 및 Peat plug利用이 만생종 왜철쭉의 揷木에 미치는 영향에 관한 硏究

沈慶久,河有美,朴永洙 成均館大學校 科學技術硏究所 1993 論文集 Vol.44 No.2

This study was carried out to propagate Rhododendron Satsuki hybrid `Bemi-Kirishima' through soft-wood cuttings in the closed mist room in connection to different concentrations of IBA, cutting media, Peat plug. The results were as follows: For the time of cutting, there were noticeable differences in the cutting on June 21 and July 8. Out of cutting media tested, the media prepared by mixing 50% vermiculite and 50 perlite(v/v ) on the treatment of IBA 1000ppm gave 100% rooting and the longest root length. Rooting of plants in the Peat plug was 93.5% and they uniform root length. In addition, Peat plug provided more space for cutting than cutting basket. It was possible that we got good cuttings and therby mass propagation through Peat plug.

미국 및 카나다와 영국에서 우리나라 自生草花類의 利用과 品種 育成

徐炳基,河有美,沈慶久 한국화훼연구회 1996 화훼연구 Vol.5 No.1

This study was carried out to investigate the Korean native wild herbaceous plants in America, Canada and England through the seed and plant nursery sources dealing with the Korean native plants. The results were as follows : 1.Korean native wild herbaceous plants introduced to America and Canada were 177 species that surveyed by U.S. national arboretum and Morris arboretum in 1985 and 1989. 2.Many nursery companies in America and Canada were dealing with 44 species of Korean native herbaceous plants from 177 species introduced in America and Canada. 3.In 1993, many nursery companies in America and Canada were dealing with Lysimachia clethroides, Liriope spicata, Pennisetum alopecuroides for. palmata and Tetragonia tetragonoides that had not been dealing with in 1989. And Sanguisorba officinalis and Patrinia scabiosaefolia were increasing than 1989. 4.Liliaceae plants from 44 species of Korean herbaceous plants dealing with in American and Canadian nursery companies were 7 species, which is the first status. And Lysimachia clethroides was dealt with the most nursery companies in America and Canada. 5.New cultivars from 12 species of Korean native herbaceous plants introduced in America and Canada were selected or bred in American and Canadian nursery companies or arboretums. And Platycodon grandiflorum had 22 cultivars including 'Albus'. 6.Liliaceae plants from 61 species of Korean herbaceous plants dealing with in English nursery companies were 12 species, which is the first status. And Campanula takesimana was dealt with the most nursery companies in England. 7.New cultivars from 18 species of Korean native herbaceous plants introduced in England were selected or bred in English nursery companies or arboretums. And Platycodon grandiflorum had 12 cultivars including 'Aximinster streaked'.

Derivation of Cell Adapted Sacbrood Virus from Korean Native Honeybee

Mi-Sun Yoo,Chang-Hee Kweon,Young-Ha Kim,Nam-Hee Kim,Ha-Na Jung,Kondreddy Eswar Reddy,Suk-Chan Jung,Seung-Won Kang 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.10

Sacbrood virus (SBV), a causative agent of larval death in honeybees, is one of the most devastating diseases in bee industry throughout the world. Lately the Korean Sacbrood virus (KSBV) induced great losses in Korean honeybee (Apis cerana) colonies. However, there is no culture system available for honeybee viruses, including SBV, therefore, the research on honeybee viruses is practically limited until present. In this study, we investigated the growth and replication of KSBV in cell cultures. The growth of KSBV was demonstrated by RT-PCR, quantitative real-time PCR, TEM and nucleotide sequence analysis. The results demonstrated that SBVshowed the replication signals in mammalian cell lines, including Vero cells without any signs of cytopathic effect (CPE). The results of RT-PCR, quantitative real-time PCR and in vivo infection with KSBV were also indicated the replication. Phylogenetic tree analysis shows our sequence included in distinct group with other SBV strains from China and Korea. It clearly showed the differenciation between field strain and attenuated strain through cell culture. The results of present study demonstrated for the first time that SBV like other animal viruses could be adapted and attenuated in cells through the sequential passages. The sequential adaptation through cell culture could result in discrepancy of pathogenicity of virus and morphological characterization. For this reason, the present results indicated that the cell adapted SBV could be a valuable tool to study the general properties of this emerging virus, including pathogenicity in the future.

Rapid Detection of Korean Sacbrood Virus (KSBV) in Honeybee (Apis cerana) using Reverse-Transcription Ultra-Rapid Real-Time Polymerase Chain Reaction

Mi Sun Yoo,Young Ha Kim,Jin Hyeong Noh,Nam Hee Kim,Ha Na Jung,Eswar Reddy Koneddy,Suk Chan Jung,Seung Won Kang 대한수의학회 2013 대한수의학회 학술대회발표집 Vol.2013 No.-

Molecular activation of NF-κB, pro-inflammatory mediators, and signal pathways in γ-irradiated mice

Ha, Young Mi,Chung, Sang Woon,Kim, Ji Min,Kim, Dae Hyun,Kim, Ji Young,Lee, Eun Kyeong,Lee, Jaewon,Kim, Young Jin,Yoo, Mi Ae,Jeong, Kyu Shik,Chung, Hae Young Springer-Verlag 2010 Biotechnology letters Vol.32 No.3