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RISS 인기검색어
- 검색키워드
- 저자 : H.S. Metwally (검색결과 5 건)
- 무료
- 기관 내 무료
- 유료
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Synthesis of Some New 4H-(Pyrano and/or Piperidino)[3,2-d] Pyazoles and Pyrazolo[5,4-d] Thiopyrans
Etman, H.A.,El-Ahl, A.S.,Metwally, M.A. The Pharmaceutical Society of Korea 1994 Archives of Pharmacal Research Vol.17 No.4
1,5-diketones(3) undewent cyclization to 4H-pyrano[3,2-d]pyrazoles (4a-d),4H-piperidino[3, 2-d]pyrazole (5) and pyrazolo[5,4-d]thiopyran (6) upon treatment with P/sub 2/O/sub 5/, CH/sub 3/COONH/sub 4/ and /or P/sub 2/S/sub 5/. Moreover, treatment of (4) with CH/sub 3/COONH/sub 4/ and/or P/sub 2/S/sub 5/ afforded (5) and (6). The structures of the hitherto unknown ring systems have been confirmed by analytical and spectral data.
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Influence of Skull Anisotropic Mechanical Properties in Low-Intensity Focused Ultrasound
Metwally, M. K.,Han, H.-S.,Jeon, H. J.,Nam, S. B.,Han, S. M.,Kim, T.-S. WORLD SCIENTIFIC PUBLISHING 2016 Vol.24 No.1
<P>Low-intensity focused ultrasound (LIFU) is a new noninvasive brain stimulation technique where ultrasound is applied with low frequency and intensity to focus at a target region within the brain in order to exhibit or inhibit neuronal activity. In applying LIFU to the human brain, the skull is the main barrier due to its well-known high anisotropic mechanical properties which will affect the ultrasound focusing thereby affecting the neuromodulation or brain stimulation. This study aims at investigating the influence of the anisotropic mechanical properties of the skull on ultrasound propagation and focusing in LIFU. In this study, we used 2D finite element (FE) head models incorporating the isotropic and anisotropic properties of the skull. Three kinds of stresses were examined and shown within the skull: namely the normal stress in the direction of wave propagation (x-stress), normal stress in the transverse direction to the wave propagation (y-stress), and shear stress. Our analysis show that although most of the pressure that reaches to the brain is due to the longitudinal wave propagation through the skull, the stress in the transverse direction to the wave propagation direction (y-stress) has the main influence on the pressure profile inside the brain. The results also show that the anisotropic properties of the skull broaden the focal size about 19% and 13% in the longitudinal and transverse directions, respectively more than the case of considering the isotropic properties in the realistic 2D FE head model. The results indicate the importance of considering the anisotropic properties of the skull in practicing LIFU to achieve accurate targeting within the brain.</P>
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Kraidees, M.S.,Al-Haidary, I.A.,Mufarrej, S.I.,Al-Saiady, M.Y.,Metwally, H.M.,Hussein, M.F. Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.8
A trial was conducted to study the effect of supplemental chromium (Cr) levels from a Cr-yeast source on performance, digestibility and carcass characteristics of transport-stressed lambs. Forty-eight Naemi lambs (avg. BW 31.7 kg) were transported by truck for a distance of 1,450 km. On arrival day, the lambs were randomly allocated to four groups receiving diets supplemented with 0.0, 0.3, 0.6 or 0.9 ppm Cr. Each group consisted of four separately housed replicates of three lambs each. The lambs were fed their respective diets ad libitum for 84 d (21 d stress period, followed by 63 d growing period). Road transit of lambs resulted in a decreased (p<0.001) live body weight of 8.5%. Supplementation of Cr-yeast did not alter the performance of lambs during the stress period. Linear and quadratic increases (p<0.05) were observed in DMI and ADG, respectively, with increasing supplemental Cr levels in the diets during the growing period. Values were greater (p<0.05) by 14.7% and 20.8%, respectively, for lambs fed 0.3 ppm Cr compared to control, while those fed on the other two levels were intermediate. Over the 84-d feeding period, a trend was noted towards a slight increase in loin eye area and a decrease in body wall fat thickness for lambs fed Cr supplementation compared to the control group. This study suggests that the supplementation of Cr-yeast, especially at 0.3 ppm level, is beneficial for improving the performance of growing lambs whether the animals are stressed or not.
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Al-Mufarrej, S.I.,Al-Haidary, I.A.,Al-Kraidees, M.S.,Hussein, M.F.,Metwally, H.M. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.5
Forty-eight Naemi lambs (avg. BW 31.7 kg) were transported by truck for a distance of 1,450 km from Al-Jouf to Riyadh, Saudi Arabia. On arrival day, the lambs were randomly allocated to four groups receiving diets supplemented with 0.0, 0.3, 0.6 and 0.9 ppm organic chromium (Cr). Each group consisted of four separately housed replicates of three lambs each. The animals were fed ad libitum on a grower diet for 84 days. Blood samples were obtained shortly before transportation, upon arrival and at weekly intervals thereafter from all lambs for analysis of plasma and serum. Plasma glucose and serum cortisol, total protein, albumin, urea-N and total cholesterol concentrations were determined. A cursory clinical examination of the lambs, along with rectal temperature, was undertaken at different intervals during the experiment. The lambs were inoculated each with 2 ml i.v. chicken red blood cells (CRBC) on days 0, 21, and 42. Serum total, IgG and IgM antibody titers were determined at weekly intervals post-immunization. An in vivo intradermal hypersensitivity test was carried out on 6 lambs from each group on days 10 and 70. Transportation of the lambs resulted in a significant (p<0.001) elevation of serum cortisol, total protein and albumin levels, as well as increased plasma glucose concentration, with corresponding decrease in total cholesterol, while blood urea-N remained largely unchanged. These constituents returned to normal levels during subsequent weeks, with no significant differences in their concentrations being observed between the Cr-supplemented groups and controls. Rise in rectal temperature after transportation was reduced to a greater extent (p<0.05) in Cr-supplemented versus control lambs. Total, IgG and IgM antibody titers against CRBC rose significantly (p<0.05) during immunizations in all groups, with significantly and linearly higher (p<0.05) total and IgG titers in Cr-supplemented versus control lambs. By contrast, no significant effect due to Cr supplementation was recorded in IgG titers, which increased equally in Cr-fed and control groups. Skin thickness in response to intradermal inoculation of phytohaemagglutinin (PHA) was also significantly (p<0.01) increased as a result of Cr supplementation. These results indicate that dietary Cr supplementation might be useful during stress especially for enhancing immune responses in transport-stressed lambs.
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M.M. El-Nahass,H.S. Metwally,H.E.A. El-Sayed,A.M. Hassanien 한국물리학회 2014 Current Applied Physics Vol.14 No.2
The JeV characteristics of the Au/5,10,15, 20-tetraphenyl-21H, 23H-porphine iron (III) chloride (FeTPPCl)/ ITO device exhibits rectifying behavior in the dark which can be explained due to the formation of Schottky barrier at ITO/FeTPPCl junction and the typical junction parameters were estimated in temperatures from 302 to 368 K. The temperature dependence of DC electrical conductivity showed that FeTPPCl films behave as semiconducting materials. These results indicate that the DC electrical conduction is through an activated process having three conduction mechanisms in the investigated range of temperatures. A variable range hopping model, a polaron model and band to band transitions have been used to explain the conduction mechanisms for FeTPPCl films.
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