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Measurements of Acoustic Properties of Tofu and Acorn Curd as Potential Tissue-mimicking Materials
Li Ying,Guntur S.R.Anjaneya Reddy,Choi Min Joo,Paeng Dong-Guk The Acoustical Society of Korea 2005 韓國音響學會誌 Vol.24 No.e4
The purpose of this study is to measure the acoustic properties of Tofu and Acorn Curd (Dotori Muk), which are possibly used as tissue mimicking materials (TMMs). Due to its availability and low cost, Tofu was suggested as a TMM by several researchers who measured only sound speed and attenuation. The acoustic properties of Tofu and Muk including the backscattering coefficient were measured in this paper. Sound speed was measured by the time shift in a pulse echo setup. Attenuation coefficients and backscattering coefficients were measured by a broadband method using both 5 MHz and 10 MHz transducers in the frequency domain. The measured acoustic properties of both Tofu and Muk are observed to be similar to those of biological tissues such as beef liver or beef heart.
Park, Seong Keun,Guntur, S. R. Anjaneya Reddy,Lee, Kang Il,Paeng, Dong-Guk,Choi, Min Joo IEEE 2010 IEEE Transactions on Biomedical Engineering Vol.57 No.1
<P>The present study aims to identify a new recipe for reusable tissue mimicking phantoms that allows the optical visualization of thermal lesions produced in various applications of therapeutic ultrasound where thermal mechanisms are important. The phantom was made of polyacrylamide hydrogel containing a nonionic surface-active agent (NiSAA) as a temperature-sensitive indicator. Threshold temperature above which a thermal lesion is regarded to be formed in the phantom is controlled by selecting an NiSAA. In the present study, three NiSAAs of polyoxyethylene alkyl ether series with nominal clouding points of 66°C, 70°C, and 80°C were chosen. Test phantoms were prepared with polyacrylamide hydrogel, corn syrup and NiSAAs [5% (w/v)]. Key acoustic properties of the three NiSAA hydrogels were found to be similar to those of human liver. The phantoms were optically transparent at room temperature (25°C) and became opaque after exceeding the clouding points. The transparency was recovered on cooling, although the system demonstrated hysteresis. The phantoms were tested both in their ability to provide visualization of thermal lesions produced by high-intensity focused ultrasound and also to examine any characteristic differences in the shape of the lesions formed at different threshold temperatures. The present study suggests that the NiSAA polyacrylamide hydrogel will be of a practical use in quality assurance in various applications of therapeutic ultrasound where thermal mechanisms are important.</P>