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      • KCI등재

        껌씹기가 개복수술 환자의 장운동 회복과 구강불편감에 미치는 효과

        방설영 (Bang, Sul Yeong),정금자 (Jung, Gum Ja),정혜연 (Jung, Hye Yeon),안소현 (An, So Hyeon) 병원간호사회 2008 임상간호연구 Vol.14 No.3

        Purpose: This study was aimed to investigate the effects of gum-chewing on the recovery of bowel movement and oral cavity discomfort after abdominal surgery. Method: The nonequivalent control group, non-syncronized repeated treatment design was used. A total of 99 patients were participated in the study. The 44 patients were in the experimental group and the rest in the control group. The experimental group chewed gum three times a day until they passed gas. As the patient reported gas-passing, bowel movement time, subjective symptoms of oral cavity, and oral status were recorded precisely. The frequency, percentage, ???u -test and t-test were analyzed by SPSS PC 12.0. Results: There were significant differences in bowel movement, gas passing, oral cavity symptoms, and oral status scores between the experimental and the control group. Conclusion: The findings of the study demonstrated the fact that gum-chewing helps early recovery from post-operative ileus and thirst. It is because gum chewing stimulates bowel mobility and secretion of saliva. Thus gum-chewing seems to be an effective nursing intervention in reducing post-operative side effects for patients with abdominal surgery.

      • 대구 안경테 산업의 생산체계

        정금희 경북대학교 사회과학대학 지리학과 2003 地理學論究 Vol.- No.23

        본 연구는 대구 안경테 제조업을 사례로 하여 입지변화와 생산체계의 실태와 특성을 분석한 것이다. 안경테 제조업체들은 대구시 도심에 집적함으로써 대규모 제조업체의 이전으로 인한 공백을 메우면서 도시 경제를 지속시켜주고 있다. 이는 소기업들은 소비자의 수요에 민감하게 반응하여 생산 및 기업 운영방식을 변화시킬 수 있는 유연성을 지니고 있고, 대도시에는 기업과 노동력이 집적되어 외부경제의 효과를 누릴 수 있기 때문이다. 즉 영세 소기업 제조업체는 대도시 도심에 집적함으로써 전문성을 유지하면서 상호간의 밀접한 협력관계를 통하여 규모경제의 이점을 누리고 있다. 여기에는 소기업들간의 긴밀한 상호협력 네트워크가 기반이 되고 있었다. 따라서 대구 안경테 제조업은 대도시 도심에 집적하여 협력적인 네트워크를 형성, 서로 대립하면서도 기능적으로 통합됨으로 인해 존립·발전이 가능한 것으로 판단된다. In a turning point for new world on the basis of globalization and knowledge based economies, recent regional theory gives particular emphasis to the importance of region as the factor of international competitiveness of firms, and organized substructure such as custom, routines and norms. And it has a new understanding of the informal network as well as formal organization, the exchange of innovatory tacit knowledge, and geographic proximity or cluster. This study analized spectacles manufacturing industry on the basis of RIS, such as general development process, location characteristics, production-and-marketing system including production division network. The results of this study are as follows: First, the close production division network among firms has strong intra-linkage and complicated subcontracting relation. Cooperation network among firms becomes the base of innovation. Spectacles Manufacturing firms and their related all firms consist of industrial cluster in the third industrial complex centering around Nowondong and Chimsandong. The firms can solve the problems within the area. Spin-offs from mother company are flexible. The spin-offs prefer to locate in industrial cluster for sharing the benefit of economics of scope and to maintain cooperation relation in terms of product development in co-operation, technical support, and joint use of equipment. These firms within the cluster industrial region have many opportunities to generate innovation. Second, the development network is occurred in the fields of technical development, of strategies of goods, and of marketing within a firm or among firms. There are active exchange of information on innovation and experience of staffs. Technical development is developed through co-operation research between same industrial classifications, new products are developed with buyers and information is obtained through participating in foreign exhibition and formal or informal network. Third, the network of related organization and institution is found out through studying the relation of trade association or league, government or related institution, and college or R&D center. Their roles of the network become more important as the result of the role as a local leader as well as supplier of technical support and information to small sized firms.

      • 에스트라다이올(17β-estradiol)과 에스트로겐 질항제 타목시펜에 의한 세포주기 조절 단백질 발션 조절

        김창근,신순영,김정희,이영한 한양대학교 이학기술연구소 2005 이학기술연구지 Vol.8 No.-

        타목시펨(tamoxifen)은 비스테로이성 triphenylethylene 유도체로서 항에스트로젠 기능과 유방암 성장을 억제시킨다. 그러나 함암효과에 대한 메카니즘은 완전히 밝혀지지 않았다. 본 연구에서 E2와 항에스트론제 타목시펜에 의한 세포주기 조절 단백질 변화능을 조사하였다. Tamoxigen(TAM)is a triphenylene antiestrogens which is known to inhibit the growth of some human breast cancer cells However the mechanism for the anti-tumor effect of TAM is not fully understood In the present study we investigated the effect of estradiol and TAM on the regulation of cell cycle progression.

      • KCI등재

        구내방사선사진의 프랙탈 분석을 이용한 골다공증 예측

        박금미,정연화,나경수 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.1

        Purpose : The purpose of this study was to investigate whether the fractal dimension and radiographic image brightness of periapical radiograph were useful in predicting osteoporosis. Materials and Methods : Ninety-two postmenopausal women were classified as normal, osteopenia and osteoporosis group according to the bone mineral density of lumbar vertebrae and periapical radiographs of both mandibular molar areas were taken. The ROIs of 358 areas were selected at periapical and interdental areas and fractal dimension and radiographic image brightness were measured. Results : The fractal dimension in normal group was significantly higher than that in osteoporosis group at periapical ROI (P<0.05). The radiographic image brightness in normal group was higher than that in osteopenia and osteoporosis group. There was significant difference not only between normal and osteopenia group (P<0.05) but also within osteopenia and osteoporosis group (P<0.01) at periapical ROI. Significant difference was observed not only between normal and osteopenia group but also between normal and osteoporosis group at interdental ROI (P<0.01). Positive linear relationship was weakly shown at Pearson correlation analysis between fractal dimension and radiographic image brightness. BMD significantly correlated with fractal dimension at periapical ROI (P<0.01), and BMD and radiographic image brightness significantly correlated at both periapical and interdental ROIs (P<0.01). Conclusion : This study suggests that the fractal dimension and radiographic image brightness of periapical ROI may predict BMD.

      • Prevalence and Clinical Characteristics of HCV Genotype 2 Patients with Anemia after Sovaldi + Ribavirin Therapy

        ( Jung Hwan Yu ),( Haak Cheuul Kim ),( In Hee Kim ),( Dae-ghon Kim ),( Gum Mo Jung ),( Yong Keun Cho ),( Eun Young Cho ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Aims: Sovaldi plus ribavirin therapy for chronic hepatitis C (CHC) genotype 2 patients are tolerable and highly effective in a shorter period of time than before. However, hematologic complication, especially anemia, can affect the efficacy of these drugs. The aim of this study was to investigate the prevalence of anemia and clinical characteristics of patients with anemia after sovaldi plus ribavirin treatment. Methods: Patients with CHC genotype 2 who underwent sovaldi plus ribavirin therapy at three referral hospitals in Jeollabuk-do Province from May 2016 to February 2017 were enrolled. Results: Total 95 patients (male 49, female 46) underwent sovaldi plus ribavirin therapy. The average age of the patients was 65.4 (30-89). Of 95 patient, 10 (10.5%) reduced ribavirin dose due to significant hemoglobin down. The incidence of anemia was 16.8% (16/95), 21.1% (20/95), 24.2% (23/95) at 4 weeks, 8 weeks, and 12weeks after treatment, respectively. Patients who reduced ribavirin dose showed predominantly low body mass index (BMI), hemoglobin (Hb), hamatocrit (Hct), and platelet at initial lab test. And, the patient with DM showed statistically higher hemoglobin reduction at the end of treatment. Sustained virologic response (SVR) at 12 weeks post-treatment was evaluated in 66 patients. SVR12 was found in 96.9% (64/66) patients. One patient who did not achieve SVR12 had ribavirin dose reduction due to anemia, the other underwent only 12 weeks treatment although he had liver cirrhosis. Conclusions: Most patient who underwent sovaldi plus ribavirin therapy showed higher SVR rate after treatment. However, because of ribavirin side effect, quite a few patients experienced the hemoglobin down and dose reduction. Therefore, we should pay attention to the patient who underwent sovaldi plus rivabirin, especially had lower BMI, Hb, Hct and platelet.

      • KCI등재

        Clinical results between single incision laparoscopic cholecystectomy and conventional 3-port laparoscopic cholecystectomy

        Gum O Jung,Dong Eun Park,Kwon Mook Chae 대한외과학회 2012 Annals of Surgical Treatment and Research(ASRT) Vol.83 No.6

        Purpose: The aim of our study was to compare single incision laparoscopic cholecystectomy (SILC) and conventional laparoscopic cholecystectomy (CLC) with respect to clinical outcomes. Methods: Patients with less than a 28 body mass index (BMI) and a benign gall bladder disease were enrolled in this study. From January 2011 to February 2012, 30 consecutive patients who underwent SILC were compared with 30 patients who underwent CLC during the same period. In this study, all operations were performed by one surgeon. In each group, patient characteristics and perioperative data were collected. Results: There was no significant difference in the preoperative characteristics. There was no significant difference in the postoperative laboratory result (alanine aminotransferase, aspartate aminotransferase, and alanine aminotransferase), number of conversion and complication cases, and length of hospital stay. The operation time was significantly longer in the SILC group (78.5 ± 17.8 minutes in SILC group vs. 34.9 ± 5.75 minutes in CLC group, P < 0.0001). The total nonsteroidal antiinflammatory drug usage during perioperative period showed significantly higher in SILC groups (162 ± 51 mg in the SILC group vs. 138 ± 30 mg in the CLC group), but there was no statistically significant difference in opioid usage between two groups. The postoperative pain score was significantly higher in the SILC group at second, third, and tenth postoperative day. Satisfaction of postoperative wound showed superiority in SILC group. Conclusion: SILC seems to be an acceptable alternative to CLC with acceptable results. However, it is not enough to propose any real benefits of SILC when compared with CLC in terms of operation time and postoperative pain.

      • KCI등재후보

        A Case of Liver Metastasis of Gastrointestinal Stromal Tumor That Was Resected after Treatment with Imatinib Mesylate and Sunitinib

        Gum O Jung,Kwon Mook Chae,Dong Eun Park,Hyeok Shim,Sang Hyun Park,Ki Jung Yun 한국간담췌외과학회 2010 한국간담췌외과학회지 Vol.14 No.4

        A 65-year old man underwent wedge resection for a gastrointestinal stromal tumor (GIST) of the gastric fundus in 1997. In 2003, the abdominal CT and sono-guided biopsy revealed he had a large GIST liver metastasis. He underwent treatment with 400 mg/day of imatinib mesylate. As a result, the liver metastasis markedly decreased in size. However, focal progression of the liver metastasis was observed on the follow up CT, so we increased the imatinib from 400 mg/day to 800 mg/day. We then performed extended left hepatectomy. We report here on a patient who presented with an isolated metastatic GIST to the liver, and the patient was successfully treated with imatinib therapy and hemihepatectomy.

      • KCI등재

        Gallstones are Associated with Intima-Media Thickness of Common Carotid Arteries in Men

        Jung-Hwan Kim,Jung-Gum Ryoo,Jeong-Won Lee,Ji-Hye Kim 대한가정의학회 2014 Korean Journal of Family Medicine Vol.35 No.3

        Background: The prevalence of gallstone disease is increasing in Korea. Gallstone disease and atherosclerosis share common risk factors. Ultrasonographic carotid intima-media thickness is an independent predictor of atherosclerosis. We measured the carotid intima-media thickness among men who had gallstones to establish the association between atherosclerosis and gallstones.Methods: A total of 330 men who visited the health promotion center of the IS Hallym Hospital from January 2011 to July 2012 were recruited. Both abdomen and carotid ultrasonographies were performed. Demographic, anthropometric, and biochemical data were collected.Results: The prevalence of gallstones was 6.6%. The carotid intima-media thickness, age, and body mass index were higher in subjects with gallstones (P < 0.05 for all). After Pearson correlation analysis, gallstone, age, body mass index, and fasting blood sugar were significantly associated with carotid intima-media thickness. A statistically positive association between gallstone and carotid intima-media thickness was demonstrated in a multivariate analysis adjusted for age, body mass index, and fasting blood sugar.Conclusion: Carotid intima-media thickness is higher in male subjects with gallstones, indicating that they are at greater risk for atherosclerosis.

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