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Novel Method to Improve the Microstructure and Mechanical Properties of 45 Steel
Tao Gu,Shuaixin Zhang,Yuhong Zhao,Yurong Yang,Huafeng Liu,Li Wu,Jianhua Liu,Hua Hou 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.4
Aiming at the problems of poor hardenability and low mechanical strength of 45 steel after quenching and tempering atnormal pressure, 45 steel was quenched and tempered under high pressure. The microstructure of 45 steel after high pressurequenching and tempering was analyzed by optical microscope, scanning electron microscope and transmission electronmicroscope, its hardness and compressive strength were tested by hardness tester and electronic universal testing machine,and compared with samples treated by the same process under atmospheric pressure. The results show that uniform andcompact tempered sorbite can be obtained after high pressure quenching and tempering of 45 steel, and the precipitatedgranular carbides are finely dispersed, thus improving the mechanical properties of 45 steel. Under a pressure of 3 GPa,quenching at 900 °C for 15 min and 550 °C for 60 min tempering, the hardness and compressive yield strength of 45 steelwere 36.3 HRC and 971 MPa, respectively, which were respectively 25.17% and 20.77% higher than the corresponding valuesobtained with the same process under atmospheric pressure quenching and tempering. This work provides a new method toeffectively improve the mechanical properties of 45 steel.
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Chen Lu,Cao Kai,Gu Yurong,Luo Chao,Mao Wei,Zhou Weijun,Zhu Jinwei,Zhang Huying 대한독성 유전단백체 학회 2021 Molecular & cellular toxicology Vol.17 No.3
Background Kaempferol (KMF) is a fl avone reported to have anti-oxidant and anti-infl ammatory activity. Objective The present study screened the eff ect of KMF in the animal model of spinal cord injury (SCI). Results KMF caused a signifi cant inhibition of spinal cord injury mediated oxidative stress and also suppressed the infl ammatory reactions. The treatment of KMF also inhibited the levels of p53, TGF-β1 and COX-2 whereas a signifi cant elevation in Bcl-2/Bax ratio was observed after the rats were treated with KMF. The in silico docking analysis suggested potential binding of KMF having lower energy with p53 confi rming the potential target of KMF. Conclusion The treatment of KMF exerted neuroprotective eff ect by improving the anti-oxidant status and infl ammatory response. The signifi cant spinal cord injury protective eff ect of KMF in rats was attributed by targeting p53 and Bcl-2/Bax ratio.
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