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Unusual malignant neoplasms of ovary in children: two cases report
Ghribi, Ali,Bouden, Aicha,Gasmi, Manef,Hamzaoui, Mourad The Korean Pediatric Society 2016 Clinical and Experimental Pediatrics (CEP) Vol.59 No.no.sup1
Sex cord tumors with annular tubules are known to originate from the sex cord of embryonic gonads that synthesize Sertoli cells, Leydig cells, granulosa cells, and theca cells of the ovarian stroma, while ovarian small cell carcinoma of the hypercalcemic type is a type of neuroendocrine tumor. Both these tumors are uncommon, potentially malignant neoplasms in children. We report the case of a sex cord tumor with annular tubules in an 11-year-old girl and a case of small cell carcinoma of the hypercalcemic type in a 10-year-old girl. We also discuss the prognosis and management of these tumors.
On the existence of the Tweedie power parameter implicit estimator
Abdelaziz Ghribi,Aymen Hassin,Afif Masmoudi 대한수학회 2022 대한수학회보 Vol.59 No.4
A special class of exponential dispersion models is the class of Tweedie distributions. This class is very significant in statistical modeling as it includes a number of familiar distributions such as Gaussian, Gamma and compound Poisson. A Tweedie distribution has a power parameter $p$, a mean $m$ and a dispersion parameter $\phi$. The value of the power parameter lies in identifying the corresponding distribution of the Tweedie family. The basic objective of this research work resides in investigating the existence of the implicit estimator of the power parameter of the Tweedie distribution. A necessary and sufficient condition on the mean parameter $m$, suggesting that the implicit estimator of the power parameter $p$ exists, was established and we provided some asymptotic properties of this estimator.
Unusual malignant neoplasms of ovary in children: two cases report
Ali Ghribi,Aicha Bouden,Manef Gasmi,Mourad Hamzaoui 대한소아청소년과학회 2016 Clinical and Experimental Pediatrics (CEP) Vol.59 No.no.sup1
Sex cord tumors with annular tubules are known to originate from the sex cord of embryonic gonads that synthesize Sertoli cells, Leydig cells, granulosa cells, and theca cells of the ovarian stroma, while ovarian small cell carcinoma of the hypercalcemic type is a type of neuroendocrine tumor. Both these tumors are uncommon, potentially malignant neoplasms in children. We report the case of a sex cord tumor with annular tubules in an 11-year-old girl and a case of small cell carcinoma of the hypercalcemic type in a 10-year-old girl. We also discuss the prognosis and management of these tumors.
Samir Bachouche,Tarek Ghribi,Samir Rouidi,Mohamed Etsouri,Yasmine Belkacem,Rabah Selmani,Mostapha Djellali,Hadj Raouf Aissa,Samir Grimes 한국해양과학기술원 2022 Ocean science journal Vol.57 No.3
Recently, there have been recorded findings of the pleustonic siphonophore Physalia physalis Linnæus, 1758, in different regions of Algeria. Several colonies washed ashore during March and May 2021 along the Algerian coast. Thirty colonies were observed on surface water and stranded on the beach between March and May from Beni Saf (35.30182° N;-1.40293° W) to Skikda (36.916557° N;7.162915° E). The highest number of such strandings of this species was recorded in Tipaza and Algiers. This is the first record of P. physalis in Algeria, extending the previously known distributions from the tropical and sub-tropical latitudes of Atlantic, Pacific and Indian oceans and may represent a danger to human health and the coastal economy. Strandings of P. physalis were notably associated with sea surface current and wind forces pushing P. physalis to become stranded on beaches. Our findings highlight the need for a monitoring program to be developed to understand more about trends associated with changes in the distribution and impact of this species. This work provides an update on the spatial distribution of P. physalis in the Mediterranean Sea.
Fouzai Chaima,Trabelsi Wafa,Bejaoui Safa,Marengo Michel,Ghribi Feriel,Chetoui Imen,Mili Sami,Soudani Nejla 한국독성학회 2023 Toxicological Research Vol.39 No.3
Lambda-cyhalothrin (λ-cyh) is a potential pyrethroid insecticide widely used in pest control. The presence of pyrethroids in the aquatic ecosystem may induce adverse effects on non-target organisms such as the sea urchin. This study was conducted to assess the toxic effects of λ-cyh on the fatty acid profiles, redox status, and histopathological aspects of Paracentrotus lividus gonads following exposure to three concentrations of λ-cyh (100, 250 and 500 μg/L) for 72 h. The results showed a significant decrease in saturated fatty acid (SFAs) with an increase in monounsaturated fatty acid (MUFAs) and polyunsaturated fatty acid (PUFAs) levels in λ-cyh treated sea urchins. The highest levels in PUFAs were recorded in the eicosapentaenoic acids (C20:5n-3), docosahexaenoic acids (C22:6n-3) and arachidonic acids (C20:4n-6) levels. The λ-cyh intoxication promoted oxidative stress with an increase in hydrogen peroxide (H2O2), malondialdehyde (MDA) and advanced oxidation protein products (AOPP) levels. Furthermore, the enzymatic activities and non-enzymatic antioxidants levels were enhanced in all exposed sea urchins, while the vitamin C levels were decreased in 100 and 500 μg/L treated groups. Our biochemical results have been confirmed by the histopathological observations. Collectively, our findings offered valuable insights into the importance of assessing fatty acids’ profiles as a relevant tool in aquatic ecotoxicological studies.
Improvement of Bread Quality and Bread Shelf-life by Bacillus subtilis Biosurfactant Addition
Ines Mnif,Souhail Besbes,Raoudha Ellouze,Semia Ellouze-Chaabouni,Dhouha Ghribi 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.4
The objective of the present work was to determine the effect of the addition of a microorganism derived emulsifier on the quality of bread. The effect of Bacillus subtilis SPB1 biosurfactant has been investigated in comparison to a commercial surfactant, the soya lecithin. Indeed, it led to a better shape and a greater specific volume and voided fraction of loaves. Also, results showed that SPB1 bioemulsifier addition improved considerably the texture profile of bread, mainly at a concentration of 0.075%(w/w). In fact, we showed a notable decrease of firmness, chewiness, and adhesion values with a slight increase of cohesion for bread added emulsifier. According to crumb texture evolution during storage, SPB1 biosurfactant exhibited a significant antistaling effect. Moreover, SPB1biosurfactant addition reduced significantly bread susceptibility to microbial contamination. These results proved that SPB1 biosurfactant could be of a great interest in the bread-making industry.
( Mouna Bouassida ),( Imen Ghazala ),( Semia Ellouze-chaabouni ),( Dhouha Ghribi ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.1
Biosurfactants or microbial surfactants are surface-active biomolecules that are produced by a variety of microorganisms. Biodegradability and low toxicity have led to the intensification of scientific studies on a wide range of industrial applications for biosurfactants in the field of environmental bioremediation as well as the petroleum industry and enhanced oil recovery. However, the major issues in biosurfactant production are high production cost and low yield. Improving the bioindustrial production processes relies on many strategies, such as the use of cheap raw materials, the optimization of medium-culture conditions, and selecting hyperproducing strains. The present work aims to obtain a mutant with higher biosurfactant production through applying mutagenesis on Bacillus subtilis SPB1 using a combination of UV irradiation and nitrous acid treatment. Following mutagenesis and screening on blood agar and subsequent formation of halos, the mutated strains were examined for emulsifying activity of their culture broth. A mutant designated B. subtilis M2 was selected as it produced biosurfactant at twice higher concentration than the parent strain. The potential of this biosurfactant for industrial uses was shown by studying its stability to environmental stresses such as pH and temperature and its applicability in the oil recovery process. It was practically stable at high temperature and at a wide range of pH, and it recovered above 90% of motor oil adsorbed to a sand sample.
( Maktouf Sameh ),( Amel Kamoun ),( Claire Moulis ),( Magali Remaud Simeon ),( Dhouha Ghribi ),( Semia Ellouz Chaabouni ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.4
A new Bacillus strain degrading starch, named Bacillus sp. UEB-S, was isolated from a southern Tunisian area. Amylase production using solid-state fermentation on millet, an inexpensive and available agro-resource, was investigated. Response surface methodology was applied to establish the relationship between enzyme production and four variables: inoculum size, moisture-to-millet ratio, temperature, and fermentation duration. The maximum enzyme activity recovered was 680 U/g of dry substrate when using 1.38 × 109 CFU/g as inoculation level, 5.6:1 (ml/g) as moisture ratio (86%), for 4 days of cultivation at 37oC, which was in perfect agreement with the predicted model value. Amylase was purified by Q-Sepharose anion-exchange and Sephacryl S-200 gel filtration chromatography with a 14-fold increase in specific activity. Its molecular mass was estimated at 130 kDa. The enzyme showed maximal activity at pH 5 and 70oC, and efficiently hydrolyzed starch to yield glucose and maltose as end products. The enzyme proved its efficiency for digesting raw cereal below gelatinization temperature and, hence, its potentiality to be used in industrial processes.
Mouna Bouassida,Inès Mnif,Ines Hammami,Mohamed-Ali Triki,Dhouha Ghribi 한국식품과학회 2023 Food Science and Biotechnology Vol.32 No.11
Bacillus subtilis SPB1 derived biosurfactants (BioS) proved its bio-control activity against Agrobacterium tumefaciens using tomato plant. Almost 83% of disease symptoms triggered by Agrobacterium tumefaciens were reduced. Aiming potential application, we studied lipopeptide cost-effective production in both fermentations systems, namely the submerged fermentation (SmF) and the solid-state fermentation (SSF) as well as the use of Aleppo pine waste and confectionery effluent as cheap substrates. Optimization studies using Box–Behnken (BB) design followed by the analysis with response surface methodology were applied. When using an effluent/sea water ratio of 1, Aleppo pine waste of 14.08 g/L and an inoculum size of 0.2, a best production yield of 17.16 ± 0.91 mg/g was obtained for the SmF. While for the SSF, the best production yield of 27.59 ± 1.63 mg/g was achieved when the value of Aleppo pine waste, moisture, and inoculum size were, respectively, equal to 25 g, 75%, and 0.2. Hence, this work demonstrated the superiority of SSF over SmF.