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Power-Efficient Wireless Neural Stimulating System Design for Implantable Medical Devices
Lee, Hyung-Min,Ghovanloo, Maysam The Institute of Electronics and Information Engin 2015 IEIE Transactions on Smart Processing & Computing Vol.4 No.3
Neural stimulating implantable medical devices (IMDs) have been widely used to treat neurological diseases or interface with sensory feedback for amputees or patients suffering from severe paralysis. More recent IMDs, such as retinal implants or brain-computer interfaces, demand higher performance to enable sophisticated therapies, while consuming power at higher orders of magnitude to handle more functions on a larger scale at higher rates, which limits the ability to supply the IMDs with primary batteries. Inductive power transmission across the skin is a viable solution to power up an IMD, while it demands high power efficiencies at every power delivery stage for safe and effective stimulation without increasing the surrounding tissue's temperature. This paper reviews various wireless neural stimulating systems and their power management techniques to maximize IMD power efficiency. We also explore both wireless electrical and optical stimulation mechanisms and their power requirements in implantable neural interface applications.
An Inductively-Powered Wireless Neural Recording and Stimulation System for Freely-Behaving Animals
Lee, Byunghun,Jia, Yaoyao,Mirbozorgi, S. Abdollah,Connolly, Mark,Tong, Xingyuan,Zeng, Zhaoping,Mahmoudi, Babak,Ghovanloo, Maysam IEEE 2019 IEEE transactions on biomedical circuits and syste Vol.13 No.2
<P>An inductively-powered wireless integrated neural recording and stimulation (WINeRS-8) system-on-a-chip (SoC) that is compatible with the EnerCage-HC2 for wireless/battery-less operation has been presented for neuroscience experiments on freely behaving animals. WINeRS-8 includes a 32-ch recording analog front end, a 4-ch current-controlled stimulator, and a 434 MHz <SMALL>on</SMALL>–<SMALL>off</SMALL> keying data link to an external software- defined radio wideband receiver (Rx). The headstage also has a bluetooth low energy link for controlling the SoC. WINeRS-8/EnerCage-HC2 systems form a bidirectional wireless and battery-less neural interface within a standard homecage, which can support longitudinal experiments in an enriched environment. Both systems were verified <I>in vivo</I> on rat animal model, and the recorded signals were compared with hardwired and battery-powered recording results. Realtime stimulation and recording verified the system's potential for bidirectional neural interfacing within the homecage, while continuously delivering 35 mW to the hybrid WINeRS-8 headstage over an unlimited period.</P>