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- 저자 : Gaoxiang Xu (검색결과 2 건)
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Sunfang Chen,Dan Cai,Qi Dong,Gaoxiang Ma,Chennan Xu,Xiaogang Ba,Wei Yuan,Bing Wu,Bin Fang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Background The reconstruction of tendons with large defects requires grafts with high mechanical strength and is often hindered by complications such as infection and adhesion. Hence, grafts combining the advantages of mechanical resilience and antibacterial/antiadhesion activity are highly sought after. Methods The silver nanoparticles (GA-Ag NPs) synthesized from gallic acid and silver nitrate were attached to a decellularized extracellular matrix (Decellularized Tendon crosslinking GA-AgNPs, DT-Ag). We examined the histological structure, mechanical property, morphology, Zeta potential, cytotoxicity, antibacterial properties, antioxidant and anti-inflammatory properties, and ability of the DT-Ag to treat tendon defects in animals. Results Approximately 108.57 ± 0.94 μg GA-Ag NPs loaded per 50 mg DT, the cross-linked part of GA-Ag NPs was 65.47 ± 0.57%, which provided DT-Ag with long-lasting antibacterial activity. Meanwhile, GA endowed DT-Ag with good antioxidant and anti-inflammatory activities. Additionally, The DT-Ag facilitated M2 macrophage polarization, and suppressed fibrin deposition by hindering fibroblast adhesion. Mormore, the main advantages of DT-Ag, namely its long-lasting antibacterial activity (tested using Escherichia coli and Staphylococcus aureus as models) and the ability to prevent tissue adhesion were confirmed in vivo. Conclusion The fabricated multifunctional tendon graft was highly hydrophilic, biocompatible, and mechanically resilient, and concluded to be well suited for dealing with the main complications of surgical tendon reconstruction and has bright application prospects.
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Low‑capacitance cascaded H‑bridge STATCOM for full power operation
Yalei Yuan,Juan Zhou,Yonglei Zhang,Xiangkun Zhao,Gaoxiang Xu 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.2
A cascaded H-bridge STATCOM requires large DC filter capacitors to suppress the low-frequency voltage fluctuation in each of the H-bridge cells. Keeping the voltage stress of power device unchanged, increasing the fluctuation of the DC-link voltage is a possible method to significantly reduce the required capacitance for a STATCOM. However, excessive voltage fluctuation greatly degrades the operating range of the inductive conditions. This paper proposes a universal capacitance design method that can significantly reduce the required capacitance when compared with the traditional design method. First, the inductance is constrained in the form normalized by the system impedance. Then a new analysis method between the DC-link capacitance and the operating range is introduced. Experiment results obtained on a low-power 5-level cascaded H-bridge STATCOM prototype are presented to validate the correctness of the proposed design method.
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