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Fenghu Li,Fan Mei,Shuishui Yin,Yanjun Du,Lili Hu,Wei Hong,Jiehui Li 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.1
Objective: To compare the efficacy and safety of neoadjuvant chemotherapy combined withconcurrent chemoradiotherapy (NACT+CCRT) vs. concurrent chemoradiotherapy (CCRT) inlocally advanced cer vical cancer (LACC) patients with large tumor masses. Methods: LACC patients with localized tumor diameter >4 cm, were randomly allocated in anunblinded 1:1 ratio to NACT+CCRT or CCRT groups. Patients in the NACT+CCRT group weregiven paclitaxel combined with cisplatin (TP) NACT ever y 3 weeks for 2 cycles, followed byCCRT, with the chemotherapy regimen the same as for NACT. CCRT group were given CCRTwith the same as for NACT. Results: From March 1, 2019, to June 30, 2021, 146 patients were included in the finalanalysis. Sixty-eight (93.2%) patients in the NACT+CCRT group and 66 (90.4%) patientsin the CCRT group completed the expected treatment course. The complete response (CR)rate in the NACT+CCRT group was significantly higher than in the CCRT group (87.7% vs. 67.6%, χ2=54.540, p=0.000). In the NACT+CCRT group, the 1- and 2-year overall sur vival(OS) rates were significantly higher than those in the CCRT group (96% vs. 89% and 89%vs. 79%, χ2=5.737, p=0.017). Additionally, the rate of recurrences and distant metastaseswas significantly lower in the NACT+CCRT group than in the CCRT group (4.11% vs. 7.35%,χ 2=4.059, p=0.021). Most treatment-related adverse events in both groups were grade 3. Conclusion: Compared to CCRT, NACT+CCRT might improve the treatment completionrate, increase CR rate and 1- and 2-year OS rates, and reduce distant metastases rate for LACCpatients with large tumor masses.
An Empirical Analysis of Factors Influencing the Information Service Quality of Recruitment Websites
Feng Hu,Zhiyi Rao,Jieping Li 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.12
The online recruitment industry has developed rapidly under the Internet Plus environment, but the job hunters are rarely satisfied to the overall information service quality of recruitment websites. In order to improve the information service quality of recruitment websites, and maintain the competitive advantages of the industry, we conduct an empirical analysis of the factors influencing the information service quality of recruitment websites. Based on synthesizing the service quality evaluation indicators from both domestic and foreign studies,we propose the research model and hypotheses from the perspective of job hunters. We then conduct an online survey, and perform descriptive analysis, reliability analysis, factor analysis, variance analysis, correlation analysis and regression analysis on the sample data to test the research model and hypotheses with SPSS. The results show that the information content quality, reliability, ease of use, personalization and interactivity all have significantly positive correlation with the information service quality of recruitment websites.