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        Silver Nanofibres by a Novel Electrospinning Process: Nanofibres with Plasmon Resonance in the IR Region and Thermal Hysteresis Electrical Conductivity Features

        Barakat, Nasser A. M.,Farrag, Taha E.,Kanjwal, Muzafar A.,Park, Soo-Jin,Sheikh, Faheem A.,Yong Kim, Hak WILEY-VCH Verlag 2010 European journal of inorganic chemistry Vol.2010 No.10

        <P>In this study, we have introduced electrospinning of a colloidal solution rather than the conventional sol–gel process as a novel strategy to produce silver nanofibres. Typically, a silver acetate/polyvinyl alcohol colloidal solution was successfully electrospun. Electrophoretic light scattering (ELS) and dynamic light scattering (DLS) analyses have affirmed that the electrospun solution is a colloid with a ζ-potential of –2 mV and average particle diameter of 373 ± 1 nm. Moreover, FTIR analysis affirmed that neither the polymer nor silver acetate nanoparticles were affected during the electrospinning process. Calcination of the electrospun mats at 700 °C in an argon atmosphere produced smooth and unbroken pure silver nanofibres. Surface plasmon resonance of the resultant silver nanofibres was detected at 962 nm which is biologically beneficial. Furthermore, the synthesised silver nanofibres revealed thermal hysteresis in the electrical conductivity properties. These advantageous physical features strongly suggest utilising the prepared nanofibres in various fields.</P> <B>Graphic Abstract</B> <P>Electrospinning of a colloidal silver acetate solution rather than the conventional sol–gel process was introduced as a novel strategy to produce silver nanofibres. Electrophoretic light scattering and dynamic light scattering analyses have affirmed that theelectrospun solution is a colloid. Calcination of the electrospun mats produced smooth and unbroken pure silver nanofibres. The advantageous physical features of the fibres suggest utilising the prepared nanofibres in various fields. <img src='wiley_img_2010/14341948-2010-2010-10-EJIC200900453-fig000.gif' alt='wiley_img_2010/14341948-2010-2010-10-EJIC200900453-fig000'> </P>

      • A Comparative Study of Energy Consumption Sources for Wireless Sensor Networks

        Mohammed AboZahhad,Mohammed Farrag,Abdelhay Ali 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.3

        With the development of MEMS and CMOS technologies, the implementation of a huge number of wireless distributed micro-sensors that can be simply and rapidly deployed to form highly redundant, self-configuring, and ad hoc sensor networks. Sensor nodes are generally battery- devices, the critical facets to face concern are how to minimize energy consumption of nodes, so that the lifetime of sensing nodes can be maximized. The first step to achieve this goal is to know completely the sources of energy consumption in wireless sensor networks. In this paper, sources of energy consumption at various communication layers have been studied and investigated. Moreover, the energy consumption for the components of a typical sensor node and the impact of communication protocols stack on the energy consumption are discussed. In the sequel, the sources of energy consumption in each communication layer individually are studied. Then, a survey has been provided for existing energy models and the classification of these models into physical layer, MAC layer and cross-layer energy models.

      • SCOPUSKCI등재
      • SCIESCOPUSKCI등재
      • SCIESCOPUS

        Copper Ion Cementation in Presence of a Magnetic Field

        Fadali, Olfat A.,Obaid, Mohamed,Mahmoud, Mohamed S.,Farrag, Taha E.,TaeWoo, Kim,Khalil, Khalil Abdelrazek,Barakat, Nasser A. M. VCH VERLAGSGESELLSCHAFT 2015 CHEMICAL ENGINEERING AND TECHNOLOGY Vol.38 No.3

        <P><B>Abstract</B></P><P>The effect of an electromagnetic field (EMF) on the rate of copper(II) cementation from copper sulfate solutions on a rotating iron cylinder was investigated. The studied variables were cylinder rotation speed, magnetic field strength, and magnetic field direction. The application of EMF increased the rate of cementation in both parallel and perpendicular direction of the magnetic field where the latter proved to be more effective. The rate of mass transfer under an EMF was found to be more than doubled. The enhancement of copper recovery in presence of the EMF is due to the induced motion of Fe<SUP>+</SUP><I><SUP>n</SUP></I> in the solution which is limited to a certain range of cylinder rotation speed. The power consumption for cementation of copper could be significantly reduced by utilizing EMF.</P>

      • SCISCIESCOPUS

        Ammonium phosphate as promised hydrogen storage material

        Barakat, N.A.M.,Ahmed, E.,Abdelkareem, M.A.,Farrag, T.E.,Al-Meer, S.,Al-Deyab, S.,Elsaid, K.,Nassar, M.M. Pergamon Press ; Elsevier Science Ltd 2015 International journal of hydrogen energy Vol.40 No.32

        Most of the reported hydrogen storage materials are either expensive or based on synthetically complicated compounds. Ammonium phosphates are cheap and available product; it is being used as fertilizer. These compounds could be utilized as hydrogen storage materials. Stoichiometrically, mono-, di- and tri-ammonium phosphate can lead to evolve 3.875, 7.867 and 11.903 hydrogen equivalent, respectively. Using Pt/C (20 wt %) leads to produce 17.28, 11.35 and 10.15% from the equivalent hydrogen in the mono-, di- and tri-ammonium phosphate, respectively. Analyzing the obtained gases by GC confirms evolution of pure hydrogen. Moreover, ion chromatography detects and ions in the liquid which indicates hydrolysis of the ammonium phosphate. Ni/C and Co/C NPs can be exploited as catalysts; Ni/C containing 20 wt% metal reveals comparable results to Pt/C. Overall, this study opens promising avenue to develop new catalysts to enhance the hydrolysis of ammonium phosphate to produce hydrogen. Comparing to the reported hydrogen storage materials, ammonium phosphates possess comparable hydrogen content 97.28, 118.3 and 115.72 kg/m<SUP>3</SUP> for mono-, di- and tri-ammonium phosphate, respectively which is very close to the MgH<SUB>2</SUB> (115.5 kg/m<SUP>3</SUP>) and not so far from ammonia borane (148.2 kg/m<SUP>3</SUP>). However, in contrast to these compounds, hydrogen can be released from the introduced storage materials by hydrolysis only using the proper catalyst. Furthermore, the hydrolysis process results in producing different acids; nitrous, nitric and phosphoric acid which should be considered in the reactor construction precautions.

      • KCI등재

        Development and assessment of nano drug delivery systems for combined delivery of rosuvastatin and ezetimibe

        Metwally Mohamed Ali,El-Zawahry El-Yamani Ibrahim,Ali Maher Amer,Ibrahim Diaa Farrag,Sabry Shereen Ahmed,Sarhan Omnia Mohamed 대한약리학회 2024 The Korean Journal of Physiology & Pharmacology Vol.28 No.3

        Worldwide, cardiovascular disease is the main cause of death, which accordingly increased by hyperlipidemia. Hyperlipidemia therapy can include lifestyle changes and medications to control cholesterol levels. Statins are the medications of the first choice for dealing with lipid abnormalities. Rosuvastatin founds to control high lipid levels by hindering liver production of cholesterol and to achieve the targeted levels of low-density lipoprotein cholesterol, another lipid lowering agents named ezetimibe may be used as an added therapy. Both rosuvastatin and ezetimibe have low bioavailability which will stand as barrier to decrease cholesterol levels, because of such depictions, formulations of this combined therapy in nanotechnology will be of a great assistance. Our study demonstrated preparations of nanoparticles of this combined therapy, showing their physical characterizations, and examined their behavior in laboratory conditions and vivo habitation. The mean particle size was uniform, polydispersity index and zeta potential of formulations were found to be in the ranges of (0.181–0.72) and (–13.4 to –6.24), respectively. Acceptable limits of entrapment efficiency were affirmed with appearance of spherical and uniform nanoparticles. In vitro testing showed a sustained release of drug exceeded 90% over 24 h. In vivo study revealed an enhanced dissolution and bioavailability from loaded nanoparticles, which was evidenced by calculated pharmacokinetic parameters using triton for hyperlipidemia induction. Stability studies were performed and assured that the formulations are kept the same up to one month. Therefore, nano formulations is a suitable transporter for combined therapy of rosuvastatin and ezetimibe with improvement in their dissolution and bioavailability.

      • KCI등재후보

        Adipose-Derived Mesenchymal Stem Cells and Their Derived Epidermal Progenitor Cells Conditioned Media Ameliorate Skin Aging in Rats

        Badr Omar I.,Anter Aya,Magdy Ihab,Chukueggu Marvellous,Khorshid Moamen,Darwish Mohamed,Farrag Mohamed,Elsayed Menna,Amr Youmna,Amgad Yomna,Mahmoud Tasnim,Kamal Mohamed M. 한국조직공학과 재생의학회 2024 조직공학과 재생의학 Vol.21 No.6

        BACKGROUND: Skin alterations are among the most prominent signs of aging, and they arise from both intrinsic and extrinsic factors that interact and mutually influence one another. The use of d-galactose as an aging model in animals has been widely employed in anti-aging research. Adipose tissue-derived mesenchymal stem cells (Ad-MSCs) are particularly promising for skin anti-aging therapy due to their capacity for effective re-epithelization and secretion of various growth factors essential for skin regeneration. Accordingly, we aimed to examine the potential utility of Ad-MSCs as a therapy for skin anti-aging. METHODS: In this study, we isolated and characterized adipose-derived mesenchymal stem cells (Ad-MSCs) from the epididymal fat of male Sprague Dawley rats. We assessed the in vitro differentiation of Ad-MSCs into epidermal progenitor cells (EPCs) using ascorbic acid and hydrocoritsone. Additionally, we induced skin aging in female Sprague Dawley rats via daily intradermal injection of d-galactose over a period of 8 weeks. Then we evaluated the therapeutic potential of intradermal transplantation of Ad-MSCs and conditioned media (CM) derived from differentiated EPCs in the d-galactose-induced aging rats. Morphological assessments, antioxidant assays, and histopathological examinations were performed to investigate the effects of the treatments. RESULTS: Our findings revealed the significant capability of Ad-MSCs to differentiate into EPCs. Notably, compared to the group that received CM treatment, the Ad-MSCs-treated group exhibited a marked improvement in morphological appearance, antioxidant levels and histological features. CONCLUSIONS: These results underscore the effectiveness of Ad-MSCs in restoring skin aging as a potential therapy for skin aging. BACKGROUND: Skin alterations are among the most prominent signs of aging, and they arise from both intrinsic and extrinsic factors that interact and mutually influence one another. The use of d-galactose as an aging model in animals has been widely employed in anti-aging research. Adipose tissue-derived mesenchymal stem cells (Ad-MSCs) are particularly promising for skin anti-aging therapy due to their capacity for effective re-epithelization and secretion of various growth factors essential for skin regeneration. Accordingly, we aimed to examine the potential utility of Ad-MSCs as a therapy for skin anti-aging. METHODS: In this study, we isolated and characterized adipose-derived mesenchymal stem cells (Ad-MSCs) from the epididymal fat of male Sprague Dawley rats. We assessed the in vitro differentiation of Ad-MSCs into epidermal progenitor cells (EPCs) using ascorbic acid and hydrocoritsone. Additionally, we induced skin aging in female Sprague Dawley rats via daily intradermal injection of d-galactose over a period of 8 weeks. Then we evaluated the therapeutic potential of intradermal transplantation of Ad-MSCs and conditioned media (CM) derived from differentiated EPCs in the d-galactose-induced aging rats. Morphological assessments, antioxidant assays, and histopathological examinations were performed to investigate the effects of the treatments. RESULTS: Our findings revealed the significant capability of Ad-MSCs to differentiate into EPCs. Notably, compared to the group that received CM treatment, the Ad-MSCs-treated group exhibited a marked improvement in morphological appearance, antioxidant levels and histological features. CONCLUSIONS: These results underscore the effectiveness of Ad-MSCs in restoring skin aging as a potential therapy for skin aging.

      • KCI등재

        Camellia sinesis leaves extract ameliorates high fat diet-induced nonalcoholic steatohepatitis in rats: analysis of potential mechanisms

        Mohamed Safaa H.,Shahat Abdelaaty A.,Mohamed Mohamed Ragaa,Khalil Wagdy K. B.,Salem Ahmed M.,Farrag Abdel Razik H.,Ahmed Hanaa Hamdy 한국약제학회 2021 Journal of Pharmaceutical Investigation Vol.51 No.2

        Purpose Our research aims to address and determine the effect of Camellia sinensis extract in the management of nonalcoholic steatohepatitis (NASH) in rats. Methods Forty adult female albino rats were divided into four groups. Group 1 (G1) served as the control group, while the other three groups received high-fat diet for 32 weeks to induce NASH and then were later assigned to the following groups: (G2) NASH-afflicted group which was left untreated, (G3) NASH-afflicted group treated with Camellia sinensis extract in a dose of 400 mg/kg, and (G4) NASH-afflicted group treated with Camellia sinensis extract in a dose of 200 mg/kg. Results Significant elevation in serum alanine aminotransferase, albumin, bilirubin (total and direct), cholesterol, low density lipoprotein, triglycerides, leptin, Cox-2, and CD40 values was recorded. Moreover, overexpression of hepatic tumor necrosis factor alpha and hepatocyte growth factor genes were recorded, whereas blood platelet count and serum high density lipoprotein concentration revealed significant depletion, which was paralleled by significant downregulation of hepatic adiponectin gene expression level in NASH group versus the control group. On the opposite side, treatment of NASH groups with two different doses of Camellia sinensis extract reversed the values of the measured biochemical parameters and the targeted gene expression levels when compared with the NASH group. Optical micrograph of liver tissue sections of rats treated with Camellia sinensis extract showed the observed improvement in the studied biochemical and genetic markers. Conclusion This study provides a clear evidence for the promising therapeutic potential of Camellia sinensis extract against NASH. This could be ascribed to its hepatoprotective activity, hypolipidemic effect, and anti-inflammatory potency.

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