성장글쓰기가 소아암 환아 어머니의 불안, 무력감, 죄책감, 희망감에 미치는 영향

정은선(Eunsun Jeong),허정선(Jeongsun Heo),현명호(Myoung-Ho Hyun) 대한스트레스학회 2017 스트레스硏究 Vol.25 No.1

본 연구는 성장글쓰기 프로그램이 소아암 치료 중에 있는 환아 어머니의 불안, 무력감, 죄책감, 희망감에 미치는 효과를 대기통제 집단과 비교 검증하였다. 국내 병원에서 소아암 치료 중에 있는 환아 어머니 총 28명을 대상으로 성장글쓰기 프로그램을 하는 처지집단에 14명, 통제집단에 14명을 할당하였다. 성장 글쓰기 집단은 총 3회기, 평균 7일 글쓰기 프로그램에 참여하였다. 프로그램을 진행한 결과 성장글쓰기 집단은 불안, 죄책감이 유의하게 감소하였고, 희망감은 유의하게 증가한 것으로 나타났다. 그러나 무력감에서는 유의한 효과를 나타내지 않았다. 마지막으로 본 연구의 의의와 한계점을 살피고, 추후 연구를 제언하였다. This study compared the effectiveness of group growth-writing program on anxiety, powerlessness, hope and guilt of mother with pediatric cancer patient with those of waiting-list control group. Participants were assigned to two groups: a growth-writing group (N=14), a waiting-list control group (N=14). At baseline, post-treatment and follow-up, all participants completed questionnaires. The growth-writing program was delivered in three sessions. As a result, growth-writing group showed significant decrease in anxiety, guilt and significant increase in hope compared to the waiting-list control group without any activities. However, powerlessness did not have significant change. This study examined that growth-writing could be an effective intervention for mothers with the pediatric cancer patients. Limitations and suggestions for further studies were included.

사설시조의 희극성 교육을 위한 이론적 고찰 - 제리 파버의 웃음 이론을 중심으로 -

정은선 ( Jeong Eunsun ) 서울대학교 국어교육과 2023 先淸語文 Vol.52 No.-

This study proposed a theoretical framework for the education of comicality in Saseolsijo regarding Jerry Farber’s Incongruity Theory. According to Jerry Farber, a perceiver experiences comicality through the following steps; exploring the elements of incongruity, activating opposing sets of psychological responses, and overturning the hierarchy of the opposing psychological responses. As a result, comicality provides psychological reward which varies by types of humor, which are Counter-Restriction Humor, Empathic Humor, and Derisive Humor. Those are classified depending on the incongruous elements, the perceiver’s response to them, and their psychological reward. This study proposed the stages of learners’ psychological responses to the comicality of Saseolsijo and explains each stage in detail. By applying Jerry Farber’s Incongruity theory, this study could propose a theoretical framework for perceiver’s response to Saseolsijo. This framework is useful in designing education of comicality in Saseolsijo and can help students experience their comicality.

Cks1 regulates human hepatocellular carcinoma cell progression through osteopontin expression

Kang, Yu-Seon,Jeong, Eun-Jeong,Seok, Hyun-Jeong,Kim, Seon-Kyu,Hwang, Jin-Seong,Choi, Mu Lim,Jo, Dong-Gyu,Kim, Yuna,Choi, Jinhyeon,Lee, Yeo-Jin,Jung, Eunsun,Min, Jeong-Ki,Han, Tae-Su,Kim, Jang-Seong Elsevier 2019 Biochemical and biophysical research communication Vol.508 No.1

<P><B>Abstract</B></P> <P>Precise cell cycle regulation is critical to prevent aberrant cell proliferation and cancer progression. Cks1 was reported to be an essential accessory factor for SCF<SUP>Skp2</SUP>, the ubiquitin ligase that targets p27<SUP>Kip1</SUP> for proteasomal degradation; these actions drive mammalian cell transition from G1 to S phase. In this study, we investigated the role played by Cks1 in the growth and progression of human hepatocellular carcinoma (HCC) cells. Silencing Cks1 expression abrogated osteopontin (OPN) expression in a p27<SUP>Kip1</SUP>-dependent manner in Huh7 HCC cells. OPN increased the proliferation, migration and invasion of Huh7 cells. Pharmacological inhibitor studies demonstrated that ERK1/2 signaling is responsible mainly for Cks1-mediated OPN expression. Cks1 appears to regulate ERK1/2 signaling through the expression of dual-specificity phosphatase 16 (DUSP16) because both Cks1 knockdown, which leads to DUSP16 upregulation, and DUSP16 overexpression decreased ERK1/2 phosphorylation and the resulting OPN expression. The same is true for the Cks1-mediated increases in p27<SUP>Kip1</SUP>, suggesting that Cks1 regulates OPN expression through activating ERK1/2 signaling either by suppressing DUSP16 expression or by a p27<SUP>Kip1</SUP>-dependent mechanism. Cks1 and OPN expression levels were significantly higher, but DUSP16 expression levels were significantly lower in HCC tissues than in normal liver tissues. Both Cks1 and OPN expression were negatively correlated with DUSP16 expression, whereas Cks1 expression was positively correlated with OPN expression. Moreover, combined panels for the expression levels of Cks1, DUSP16 and OPN showed significant prognostic power for the risk assessment of HCC patient overall survival. In conclusion, our data propose a novel function for Cks1 as a tumor promoter through the expression of the strongly oncogenic protein OPN in HCC.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cks1 promotes OPN expression in human HCC cells. </LI> <LI> The Cks1-mediated upregulation of DUSP16 or p27<SUP>Kip1</SUP> decreased OPN expression. </LI> <LI> DUSP16- or p27<SUP>Kip1</SUP>-mediated ERK1/2 inactivation is responsible for OPN abrogation. </LI> <LI> Cks1, DUSP16 and OPN may be a useful prognostic biomarker panel for HCC patients. </LI> </UL> </P>

Enhancing Automotive Motor Anomaly Detection with Mel Spectrogram Image Transformation

Eunsun YUN,Minjoong JEONG 한국콘텐츠학회 2023 한국콘텐츠학회 ICCC 논문집 Vol.2023 No.12

중등 예비 과학 교사의 자유 탐구 수행 능력 분석

이은선 ( Eunsun Lee ),정은영 ( Eunyoung Jeong ) 부산대학교 과학교육연구소 2016 교사교육연구 Vol.55 No.4

중등학교 과학 수업에서 자유 탐구를 효과적으로 운영하기 위한 방안으로 중등 예비 과학 교사들이 자유 탐구 수행 능력을 갖추고 자유 탐구의 취지와 효과를 인식할 필요가 있다. 이 연구에서는 자유 탐구를 수행한 중등 예비 과학 교사들의 자유 탐구 보고서를 분석하여 자유 탐구 수행 능력을 조사하였다. 광역시 소재 사범대학에서 2012∼2015학년에 생물교육론을 수강한 예비 교사 80명이 자유 탐구를 수행한 뒤에 작성한 29편의 보고서를 자유 탐구 보고서 평가 틀에 따라 평가 하였다. 그 결과, `주제 및 동기`, `이론적 배경`, `결과`, `결론` 영역에서는 상 수준, `탐구 과정`, `보고서 형식` 영역에서는 중 수준, `참고문헌`에서는 하 수준이 많이 나타났다. 중등 예비 과학 교사는 탐구의 목적과 내용을 명확하게 제시하고, 수집한 자료를 표와 그래프로 나타내고 해석할 수 있는 능력과 논리적으로 결론을 도출할 수 있는 능력은 갖추고 있지만, 주제 및 동기의 창의성과 유용성, 가설 설정, 참고문헌 작성 측면에서 낮은 수준을 나타내었다. 중등 예비 과학 교사에게 자유 탐구를 수행하고 탐구 보고서를 작성하는 기회를 제공하고, 부족한 탐구 능력을 향상시킬 수 있는 방안을 모색하여 자유 탐구를 지도할 수 있는 역량을 갖추게 할 필요가 있다. Pre-service science teachers should develop their free-inquiry abilities and recognize the intention and the effect of free-inquiry to conduct it effectively in secondary school science class. In this study, pre-service science teachers` ability for doing free-inquiry was investigated by the analysis of their free-inquiry reports. A total of 80 pre-service teachers performed free-inquiries at biology education course at the college of education in the second semester of from 2012 to 2015. 29 reports written by them were evaluated according to the evaluation framework of free inquiry report. The results of this study show that the pre-service teachers received good grades in `topic and motive`, `rational`, `result`, `conclusion` and average grades in `inquiry process` and `report form`, and poor grades in `reference`. Pre-service teachers have the ability to `present a purpose of inquiry`, to `transform the data`, to `analyze the data`, and to `draw a conclusions logically`. However, they have a lack of abilities in `creativity and usefulness of topic and motive`, `hypothesizing`, and `making up a reference`. These finding suggested that pre-service science teachers should have increased experiences in doing free-inquiry in order to have competency to teach free-inquiry in secondary school.

중등 예비 과학 교사의 자유 탐구 활동 중에 겪은 어려움과 인식 조사

이은선 ( Eunsun Lee ),정은영 ( Eunyoung Jeong ) 韓國生物敎育學會 2016 생물교육 Vol.44 No.4

Pre-service science teachers need to develop their free-inquiry abilities and recognize about the intention and the effect of free-inquiry to conduct it effectively in secondary school science class. In this study, the difficulties during pre-service science teachers` free-inquiry activities and their perception about free-inquiry was investigated by questionnaire and interview. 80 pre-service teachers performed free-inquiry at biology education course of college of education in second semester of 2012∼2015. They replied to the questionnaire and 16 pre-service teachers who took a biology education course in 2015 were interviewed. They have suffered from preparing material, place, time schedule, inquiry process, and topic selection. When they selected the topic, they attempted to choose the interesting one with group members using the internet and related books. It was difficult for them to select the topic which was available in fixed period. They had difficulties in preparing material and controlling variables at `performing` stage, and writing and presenting a report at `presentation` stage. Pre-service teachers gave responses that they had a chance of self-directed learning and their scientific knowledge has improved. Also they expanded understanding of free-inquiry. They gave positive responses that free-inquiry was a activity for secondary school students because of enhancing their interest of science and inquiry skill. Also pre-service teachers said that they would consider selecting the topic, interest, and cooperation during teaching free-inquiry. In conclusion, it is suggested that pre-service science teachers should have an experience doing free-inquiry in order to have competency to teach free-inquiry in secondary school.

Maker Seed Phantom을 이용한 표적위치의 정확성 평가

장은성(Eunsun Jang),정봉재(Bongjae Jeong),임인철(Inchul Im),강수만(Suman Kang) 한국방사선학회 2011 한국방사선학회 논문지 Vol.5 No.2

선형가속기에 설치된 OBI (On-Board Imager™, Varian Medical Systems, USA) 의 정도관리는 일간 및 주간으로 하고 있으며 이때 기하학적인 정확성은 매우 중요하게 된다. 본 실험에서는 4개월간 선형가속기의 OBI 장치 정도관리용 팬톰을 사용하여 일간과 주간으로 선형가속기의 기계적인 중심점(isocenter)과 가시화된 레이저의 중심점의 일치정도 및 OBI 장치 및 레이저의 중심점을 비교하여 데이터화함으로써 OBI 장치의 기계적 정확성과 정도관리용 팬톰을 사용하여 일간, 주간으로 선형가속기 환자위치 및 레이저의 등 중심점을 체크하여 데이터화함으로써 사후관리 및 환자치료 성적을 높일 수 있다고 사료된다. Accuracy control of Linear accelerator installed in OBI is done daily and weekly and importance of accuracy multiplies exponentially at that moment. Purpose of this experiment is everyday and twice a week over a four month period (march~june) 2009 year to confirm maintenance of accuracy through Quality control of OBI. In short, measurement of exponentially multiplying accuracy of OBI and regular accuracy control was able to maintain accuracy from the center of treatment within 0.1 cm. Therefore, evaluation of exponentially multiplying accuracy using OBI accuracy control linear accelerator phantom on daily, weekly basis was confirmed.

Airway management in pediatric tongue flap division for oronasal fistula closure: A case report

So, Eunsun,Yun, Hye Joo,Karm, Myong-Hwan,Kim, Hyun Jeong,Seo, Kwang-Suk,Ha, Hyunbin The Korean Dental Society of Anesthsiology 2018 Journal of Dental Anesthesia and Pain Medicine Vol.18 No.5

Oronasal fistulae (ONF) could remain after surgery in some patients with cleft palate. ONF ultimately requires intraoral surgery, which may lead to perioperative airway obstruction. Tongue flap surgery is a technique used to repair ONF. During the second surgery for performing tongue flap division, the flap transplanted from the tongue dorsum to the palate of the patient acts as an obstacle to airway management, which poses a great challenge for anesthesiologists. In particular, anesthesiologists may face difficulty in airway evaluation and patient cooperation during general anesthesia for tongue flap division surgery in pediatric patients. The authors report a case of airway management using a flexible fiberoptic bronchoscope during general anesthesia for tongue flap division surgery in a 6-year-old child.

A retrospective analysis of outpatient anesthesia management for dental treatment of patients with severe Alzheimer's disease

So, Eunsun,Kim, Hyun Jeong,Karm, Myong-Hwan,Seo, Kwang-Suk,Chang, Juhea,Lee, Joo Hyung The Korean Dental Society of Anesthsiology 2017 Journal of Dental Anesthesia and Pain Medicine Vol.17 No.4

Background: The number of patients with Alzheimer's disease is growing worldwide, and the proportion of patients requiring dental treatment under general anesthesia increases with increasing severity of the disease. However, outpatient anesthesia management for these patients involves great risks, as most patients with Alzheimer's disease are old and may show reduced cardiopulmonary functions and have cognitive disorders. Methods: This study retrospectively investigated 43 patients with Alzheimer's disease who received outpatient anesthesia for dental treatment between 2012-2017. Pre-anesthesia patient evaluation, dental treatment details, anesthetics dose, blood pressure, duration and procedure of anesthesia, and post-recovery management were analyzed and compared between patients who underwent general anesthesia or intravenous sedation. Results: Mean age of patients was about 70 years; mean duration of Alzheimer's disease since diagnosis was 6.3 years. Severity was assessed using the global deterioration scale; 62.8% of patients were in level ${\geq}6$. Mean duration of anesthesia was 178 minutes for general anesthesia and 85 minutes for intravenous sedation. Mean recovery time was 65 minutes. Eleven patients underwent intravenous sedation using propofol, and 22/32 cases involved total intravenous anesthesia using propofol and remifentanil. Anesthesia was maintained with desflurane for other patients. While maintaining anesthesia, inotropic and atropine were used for eight and four patients, respectively. No patient developed postoperative delirium. All patients were discharged without complications. Conclusion: With appropriate anesthetic management, outpatient anesthesia was successfully performed without complications for dental treatment for patients with severe Alzheimer's disease.

반영구 눈썹 문신의 지연성 부작용 2예: 육아종성 반응에 대한 국내 문헌고찰 및 증례 보고

홍은선 ( Eunsun Hong ),이정덕 ( Jeong Deuk Lee ),조상현 ( Sang Hyun Cho ),우유리 ( Yu Ri Woo ),김혜성 ( Hei Sung Kim ) 대한피부과학회 2020 대한피부과학회지 Vol.58 No.5

Cosmetic facial tattoo as semi-permanent make-up for the eyebrows is gaining popularity in Korea. Consequently, the incidence of tattoo-related complications, including local skin infections, allergic reactions, and non-allergic granulomatous reactions, is also increasing. Herein, we report two cases of granulomatous reactions to semi-permanent eyebrow tattoos. Clinicians should always keep in mind that both systemic sarcoidosis and delayed complications associated with tattooing can manifest as granulomatous reactions. Therefore, every granulomatous reaction at the tattoo site should be evaluated to differentiate sarcoidosis from foreign body granuloma. (Korean J Dermatol 2020;58(5):334∼339)