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스트론튬 이온이 무모 생쥐의 표피 투과 장벽 회복에 미치는 영향
김현정 ( Hyun Jeong Kim ),김민정 ( Min Jung Kim ),정세규 ( Se Kyoo Jeong ),최기주 ( Ki Ju Choi ),서정택 ( Jeong Taek Seo ),최응호 ( Eung Ho Choi ),안성구 ( Sung Ku Ahn ),이승헌 ( Sung Hun Lee ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.11
Background: Several ions, such as calcium or magnesium ions, are reported to have regulatory effects on epidermal permeability barrier homeostasis. Recently, it has been suggested that strontium ion can play a substitutive role for calcium ion in various cellular reactions. Objective: This study was conducted to investigate the effects of strontium ion, either alone or in combination with calcium or magnesium ions, on epidermal permeability barrier homeostasis. Methods: Female hairless mice were used to study the effects of various ions on epidermal permeability barrier recovery. Calcium chloride solution, magnesium chloride solution or strontium chloride solution were topically applied to barrier-disrupted skin, either alone or simultaneously. Change of transepidermal water loss, which represents permeability barrier function, was measured by TEWameter and morphological change was also observed by light and electron microscopy. Results: Topical application of strontium chloride solution accelerated permeability barrier recovery rate, compared with vehicle-applied skin. Magnesium chloride solution also accelerated barrier recovery rate, as reported in previous studies. Interestingly, simultaneous application of strontium and calcium ions significantly accelerated barrier recovery rate, compared to application of strontium or calcium ion alone. Nile red staining confirmed the increased neutral lipid deposition in strontium ion applied skin. Electron microscopic observation also revealed an increased lamellar body secretion in strontium ion applied skin. Conclusion: Strontium ion can play a regulatory role in epidermal permeability barrier homeostasis due to, at least in part, its competitive action on calcium ion for the same ion channel. (Korean J Dermatol 2006;44(11):1309~1316)
( Pritam Thapa ),( Eun Kyung Kim ),( Mahesh Raj Nepal ),( Ki Sun Jeong ),( Mi Jeong Kang ),( Keumhan Noh ),( Sang Kyu Lee ),( Hye Gwang Jeong ),( Jun Ho Lee ),( Tae Cheon Jeong ),( Eung Seok Lee ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
As a replacement for chlorofluorocarbons that cause ozone depletion, 1-bromopropane has been widely used in work place. In the present study, the formation of N<sup>7</sup>-guanine adduct in DNA by 1-bromo-propane was evaluated in vitro to elucidate the possi-ble mechanism of its toxic action. N<sup>7</sup>-Propyl guanine was chemically synthesized and structurally character-ized by NMR, UV, HPLC, and liquid chromatography-electro spray ionization mass spectrometry (LC- ESI MS) for using as a reference standard. An incubation of 2``-deoxyguanosine with 1-bromopropane produced N<sup>7</sup>_propyl adduct, which was identified by UV, HPLC and ESI-MS. In addition, N<sup>7</sup>-guanine adduct was also identified from the incorporation of calf thymus DNA with 1-bromopropane at the physiological condition by LC-ESI MS. Furthermore, the production of adduct was proportional to the amounts of 1-bromopropane used. These results indicated that the molecular mecha-nism underlying toxic effects of 1-bromopropane would be associated with the adduct formation on DNA at least in part.
A Medium-Maturing, Dull Cultivar ‘Baegjinju 1’
Ha-Cheol Hong,Sae-Jun Yang,Jeom-Ho Lee,O-Young Jung,Chang-Ihn Yang,Yong-Hwan Choi,Yeon-Gyu Kim,Kyu-Seong Lee,Im-Soo Choi,Young-Chan Cho,Myeong-Ki Kim,Jeong-Il Lee,Eung-Ki Jeong,Jae-Hwan Roh,Ki-Jong Ki 한국육종학회 2012 한국육종학회지 Vol.44 No.1
다양한 용도의 가공용 품종을 육성할 목적으로 1995년 하계에 아밀로스함량이 낮은 일품벼 변이체 Ilpum (MNU)-10- 2-GH1-3을 모본으로 하고 양질 내도복성인 서안벼를 부본으로 교배하여 SR21716-30-2-3-1을 선발하여 ‘수원491호’로 계통명을 부여한 후 2003년-2005년 3개년 간 지역적응시험을 실시한 결과 그 우수성이 인정되어 2005년 12월 직무육성 신품종 선정위원회에서 국가목록등재품종으로 선정됨과 동시에 ‘백진주1호’로 명명하였다. 출수기는 보통기 재배에서 평균 출수기가 8월 20일로 ‘화성벼’보다 10일 정도 늦은 중만생종이며, 벼키는 86 cm, 이삭길이는 22 cm로 ‘화성벼’와 비슷하고, 주당수수는 10개로 ‘화성벼’보다 3개 적으나, 이삭당 벼알수는 121개로 ‘화성벼’보다 25개 많다. 도열병에는 안정적이나, 흰잎마름병 및 바이러스병과 벼멸구 및 애멸구 저항성은 약하다. ‘백진주1호’는 성숙기 하엽노화가 늦은 반면 수발아율은 ‘화성벼’에 비해 낮았고, 춘천 냉수처리 검정에서 적고발현은 적었으나, 임실율이 ‘화성벼’보다 낮았으며, 도복에 강하다. ‘백진주1호’는 단원립으로 쌀 외관은 찹쌀과 같은 뽀얀 특성을 지니고 있으나, 아밀로스함량이 11.5%로 메벼와 찰벼의 중간특성이고, 도정율은 ‘화성벼’와 비슷한 특성을 나타냈다. 보통기재배 평균 쌀 수량은 중부평야 2개소 및 남부평야 4개소에서 4.92 MT/ha로 ‘화성벼’와 남평벼보다 8% 적었으며, 재배적지는 중부평야 및 남부평야이다. ‘Baegjinju 1’ is a new Japonica rice variety developed from a cross Ilpum (MNU)-10-2-GH1-3 and ‘Seoanbyeo’ by a rice breeding team of National Institute of Crop Science, RDA, during the period from 1995 to 2005. This variety has heading date of August 23 in central plain area of Korea. It has a good semi-elect plant type and resistance to lodging with strong culm. The number of panicles/hill of ‘Baegjinju 1’ is more than that of ‘Hwaseongbyeo’, and milled rice of that shows dull and medium short grain. It has very low amylose content (11.5%) and similar gelatinization temperature and good texture characteristics of cooked brown and milled rice compared with ‘Baegjinju’. It has moderate to leaf blast, but susceptible to bacterial blight, virus disease and insect pests. The yield performance of this variety is about 4.92MT/ha in milled rice in local adaptability test for three years (2003-2005). ‘Baegjinju 1’ is adaptable to central and southern plain areas of Korea
정창기,주언경,김정구,이응돈 경북대학교 전자기술연구소 1995 電子技術硏究誌 Vol.16 No.2
Error control performance of (8,3) DC-free error control code for various decoding methods is analyzed and compared in this paper. The possible decoding methods considered in this paper are hard decision decoding with and without retransmission and soft decision decoding. For soft decision decoding, the performance is much better than hard decision decoding without retransmission. In addition, as signal-to-noise ratio increases, the residual bit error rate of soft decision decoding is even lower than that of hard decision decoding with retransmission.
Evaluation of Agronomic Stability of North Korean Rice Varieties using Statistical Models
Jeong, O-Young,Lee, Jeom-Ho,Hong, Ha-Cheol,Jeong, Eung-Gi,Paek, Jin-Soo,Yang, Chang-Ihn,Jeon, Yong-Hee,Kim, Myeong-Ki,Lee, Kyu-Seong,Yang, Sae-Jun,Lee, Young-Tae The Korean Society of Crop Science 2008 한국작물학회지 Vol.53 No.1
This experiment was carried out to evaluate the agronomic stability of North Korean rice varieties using the statistical model developed by Grafius, Finlay, and Ever hart. The lowest yearly variation based on coefficients of variation was found in Hannam 29 for number of panicles per hill, in Sijoong 9 for number of grains per panicle, in Pyeongyang 3 for ripened grain ratio, in Sijoong 16 for 1,000 grain weight, and in Yeomju 1 for grain yield. By Grafius's model, Pyeongbook 3, Weonsan 66 in early maturing groups and Seohaechalbyeo in medium maturing groups show stable for 3 years. Weonsan 66 in early maturing groups and Seohaechalbyeo in medium maturing groups were found to be highly stable as analyzed by both Finlay and Wilkinson's model and Everhart & Russell's model. With reference to three models, Weonsan 66 was highly stable for 3 years with showing more yield than Odaebyeo in early maturing groups while Seohaechalbyeo was highly stable for 3 years with showing high yield than Hwaseongbyeo in medium maturing groups above $5\;t\;ha^{-1}$ of milled rice respectively.
Fabrication of UV imprint stamp using diamond-like carbon coating technology
EUNG-SUG LEE(이응숙),JUN-HO JEONG(정준호),KI-DON KIM(김기돈),YOUNG-SUK SIM(심영석),DAE-GEUN CHOI(최대근),JUNHYUK CHOI(최준혁),TAE-WOO LIM(임태우),SANG-HU PARK(박상후),DONG-YOL YANG(양동열),NAM-GOO CHA(차남구),IN-KWON KIM(김인권),JIN- 대한기계학회 2005 대한기계학회 춘추학술대회 Vol.2005 No.11
The two-dimensional (2D) and three-dimensional (3D) diamond-like carbon (DLC) stamps for ultraviolet nanoimprint lithography (UV-NIL) were fabricated using two kinds of methods, which were a DLC coating process followed by the focused ion beam (FIB) lithography and the two-photon polymerization (TPP) patterning followed by nano-scale thick DLC coating. We fabricated 70 ㎚ deep lines with a width of 100 ㎚ and 70 ㎚ deep lines with a width of 150 ㎚ on 100 ㎚ thick DLC layers coated on quartz substrates using the FIB lithography. 200 ㎚ wide lines, 3D rings with a diameter of 1.35 ㎛ and a height of 1.97 ㎛, and a 3D cone with a bottom diameter of 2.88 ㎛ and a height of 1.97 ㎛ were successfully fabricated using the TPP patterning and DLC coating process. The wafers were successfully printed on an UV-NIL using the DLC stamp. We could see the excellent correlation between the dimensions of features of stamp and the corresponding imprinted features.
High-throughput step-and-repeat UV-nanoimprint lithography
Eung-sug Lee,Jun-ho Jeong,Young-suk Sim,Ki-don Kim,Dae-geun Choi,Jun-hyuk Choi 한국물리학회 2006 Current Applied Physics Vol.6 No.1l
UV-NIL has shown promise as new disruptive technology to displace photolithography in patterning nano features. This method is attractive because of their high-throughput with easy operation at room temperature and low pressure with low-cost. In this paper, a new UV-NIL process is proposed to apply a large-area stamp to a high-throughput step-and-repeat process at atmospheric conditions, utilizing additive gas pressurization and an elementwise patterned stamp (EPS), which consists of elements separated by channels. With the proposed method, only four imprints were required to press an 8 in. wafer. EPS features measuring 50–80 nm were successfully transferred onto the wafers. The experiments demonstrated that a 5 · 5 in.2. EPS could be used with a step-and-repeat UV-NIL process to imprint 8 in. wafers under atmospheric conditions.