Effect of a 5% naproxen patch on reducing pain caused by separators prior to fixed orthodontic treatment

Eslamian, Ladan,Rad, Nazila Akbarian,Nobar, Behnam Rahbani,Mortazavi, Seyed Alireza The Korean Dental Society of Anesthsiology 2018 Journal of Dental Anesthesia and Pain Medicine Vol.18 No.3

Background: The pain involved in orthodontic treatments may involve inflammatory processes. This study evaluated the effect of using a naproxen patch for pain reduction in the separating stage of fixed orthodontic treatment. Methods: In this double-blind, randomized, controlled clinical trial of 35 orthodontic patients (age: 14-19 years) who had pain during separator placement, each patient randomly placed naproxen and placebo patches in the first permanent molar region, in opposite quadrants of the same jaw. Patches were replaced every 8 hours until 3 days after separator placement. Patients recorded their pain perception at 2, 6, and 24 hours, and on days 2 (6 PM), 3 (10 AM and 6 PM), and 7 (10 AM and 6 PM), using a visual analog scale. Mean pain scores were compared for the two patches, and effects of sex and age thereon determined. Results: Data from 29 patients (21 girls, eight boys) were analyzed. Mean pain values decreased over time for both patches (P < 0.001). Recorded pain did not differ significantly between the sexes (P = 0.059) or between those aged <16 and those ${\geq}16years$ (P = 0.106). Mean pain recorded with naproxen patches was statistically significantly less than that with placebo patches at all time points (P = 0.004). Conclusion: The naproxen patch was more efficient than the placebo patch for reducing pain at all time points. The highest pain score was recorded at 6 hours, and the least pain was recorded at the $7^{th}$ day after separator placement.

Association of nutrition risk screening 2002 and Malnutrition Universal Screening Tool with COVID-19 severity in hospitalized patients in Iran

Ghazaleh Eslamian,Sohrab Sali,Mansour Babaei,Karim Parastouei,Dorsa Arman Moghadam 대한중환자의학회 2022 Acute and Critical Care Vol.37 No.3

Background: Malnutrition affects normal body function and is associated with disease severity and mortality. Due to the high prevalence of malnutrition reported in patients with coronavirus disease 2019 (COVID-19), the current study examined the association between malnutrition and disease severity in hospitalized adult patients with COVID-19 in Iran.Methods: In this prospective observational study, 203 adult patients with COVID-19 verified by real-time polymerase chain reaction test and chest computed tomography were recruited from those admitted to a university hospital in Iran. To determine COVID-19 intensity, patients were categorized into four groups. Malnutrition assessment was based on the Malnutrition Universal Screening Tool (MUST) and nutrition risk screening score (NRS-2002). An ordinal regression model was run to assess the association between malnutrition and disease severity.Results: In the studies sample of Iranian patients with COVID-19, 38.3% of patients had severe COVID-19. According to NRS-2002, 12.9% of patients were malnourished. Based on MUST, 2% of patients were at medium, and 13.4% of patients were at high risk of malnutrition. Malnutrition was associated with a higher odds of extremely severe COVID-19 according to NRS-2002 (odds ratio, 1.38; 95% confidence interval, 0.21–2.56; P=0.021).Conclusions: Malnutrition was not prevalent in the studies sample of Iranian patients with COVID-19; however, it was associated with a higher odds of extremely severe COVID-19.

Associations between systemic inflammation and intestinal permeability with Onodera's prognostic nutritional index in critically ill patients

Seyed Hossein Ardehali,Ghazaleh Eslamian,Shirin Malek 대한중환자의학회 2021 Acute and Critical Care Vol.36 No.4

Background: Malnutrition is a serious condition in critically ill patients. The aim of this study is to evaluate the relationships between the Onodera’s prognostic nutritional index (OPNI) and intestinal permeability and between OPNI and systemic inflammation in critically ill patients. Methods: This was a cross-sectional study conducted in the general intensive care unit (ICU) of a university-affiliated hospital. A total of 162 patients admitted between May 2018 and December 2019, was included in the study. The OPNI was calculated at admission and categorized as ≤40 or >40. We assessed plasma endotoxin and zonulin concentrations as markers of intestinal permeability as well as serum interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) as markers of systemic inflammation upon admission under stringent conditions. The relationships between these markers and OPNI were assessed after adjusting for potential confounders through estimation of a binary logistic regression model. Results: Median (interquartile range) hs-CRP, IL-6 zonulin, and endotoxin were significantly greater in the low OPNI subgroup than in the high OPNI subgroup (all P<0.05). Multivariate analyses showed significant association between serum IL-6 (odds ratio [OR], 0.88; 95% confidence interval [CI], 0.64–0.96), serum hs-CRP (OR, 0.77; 95% CI, 0.53–0.92), plasma endotoxin (OR, 0.81; 95% CI, 0.72– 0.93), and plasma zonulin (OR, 0.83; 95% CI, 0.75–0.98) levels with OPNI in the overall population. Conclusions: Our results provide evidence that higher plasma endotoxin, zonulin, IL-6, and hsCRP levels are associated with progressively lower OPNI in mixed ICU populations, particularly in surgical ICU patients.

Monitoring the Effects of Drought on Vegetation Cover and Ground Water Using MODIS Satellite Images and ANN

Atta Areffian,Saeid Eslamian,Maryam Kiani Sadr,Ali Khoshfetrat 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.3

The main aim of the study was to investigate the effects of drought on vegetation cover and ground water resources. In the present study, an available climatic data series (2001 − 2017) for 9 synoptic stations in Lorestan province were analyzed to detect wet and dry years using Standardized Precipitation Index (SPI). Furthermore, a long data series of Moderate Resolution Imaging Spectroradiometer (MODIS) data was analyzed by remote sensing data and the Normalized Difference Vegetation Index (NDVI) maps have been produced for the study period (2001 − 2017). For all data, Kolmogorov-Smirnov test and Pearson Correlation Coefficient test between SPI and NDVI were used based on the data resource and normality test. In addition, the relationship between rainfall and groundwater levels was investigated using artificial neural network (ANN). During the study period, 2008 and 2015 were selected as dry and wet years based on SPI values, respectively. The values of the NDVI in the wet year (2015) are significantly higher than the values in the dry year (2008) at a 99% confidence level. Spatial variation of SPI shows that for intensive drought conditions (2008) and wet year (2015) the northern part of Lorestan province had the highest variation in comparison with other parts of the study area. Generally, the results of the present study show that MODIS data in a mountainous area could be a key tool in detecting the effects of intensive drought on natural vegetation cover. Furthermore, ground water level showed a significant correlation with the 3-month delay of monthly precipitation.

Investigation of well test behavior in gas condensate reservoir using single-phase pseudo-pressure function

Seyed Hamidreza Yousefi,Fariborz Rashidi,Alireza Eslamian 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.1

Gas condensate reservoirs present complicated thermodynamic behavior when pressure falls below the dew point pressure, due to fluid dropout and change in the fluid composition. Condensate blockage in the near wellbore region reduces the well deliverability.Mixture composition change in the reservoir makes the interpretation of well tests in gas condensate reservoirs a serious challenge. In this study, at first the capillary number effect and Non-Darcy Flow on compositional simulation of gas condensate reservoirs were investigated and then well test analysis was carried out. The main objective of this work was to examine gas condensate well test analysis using single-phase gas pseudopressure and radial composite model assuming capillary number effect and Non-Darcy Flow. For this purpose some fluid samples were selected and results compared. Results indicate that estimation of reservoir properties below the dew point is in good agreement with actual input, particularly for lean fluid samples.

Combination of Exercise and Acupuncture Versus Acupuncture Alone for Treatment of Myofascial Pain Syndrome: A Randomized Clinical Trial

Bina Eftekharsadat,Elmira Porjafar,Fariba Eslamian,Seyed Kazem Shakouri,Hamid Reza Fadavi,Seyed Ahmad Raeissadat,Arash Babaei-Ghazani 사단법인약침학회 2018 Journal of Acupuncture & Meridian Studies Vol.11 No.5

Myofascial pain syndrome (MPS) is a common musculoskeletal disorder. This study was designed to compare the effects of aerobic exercise plus acupuncture with acupuncture alone in treatment of patients with MPS. Sixty-four patients (55 female and 9 male) with MPS in their neck and shoulders participated in the study with mean age of 33.1 ± 6.4 years. Participants were randomly allocated to aerobic exercise plus acupuncture (n = 32) or acupuncture alone (n = 32) groups. Outcome measurements included visual analog scale, pressure pain threshold, neck disability index, and quality of life that was measured with QoL-SF36 scale. Each group received 10 sessions of acupuncture in combination with aerobic exercise or acupuncture alone. The outcome measures were evaluated at baseline, at the end of the last treatment session, and at 1-month follow-up visit. While participants were waiting for their 1-month follow-up visit, the patients who received combination therapy were asked to continue their aerobic exercise by jogging 40 minutes a day. Although mean visual analog scale, pressure pain threshold, neck disability index, and QoL-SF36 were significantly improved in both groups (p < 0.001), there was no statistically significant difference among the measures between the two groups throughout the evaluated sessions. The interaction effect of time and groups did not show any significant difference among the outcome measures (p > 0.29).

Association of vitamin D deficiency with COVID-19 severity and mortality in Iranian people: a prospective observational study

Alireza Fatemi,Seyed Hossein Ardehali,Ghazaleh Eslamian,Morvarid Noormohammadi,Shirin Malek 대한중환자의학회 2021 Acute and Critical Care Vol.36 No.4

Background As the coronavirus disease 2019 (COVID-19) pandemic continues to escalate, it is important to identify the prognostic factors related to increased mortality and disease severity. To assess the possible associations of vitamin D level with disease severity and survival, we studied 248 hospitalized COVID-19 patients in a single center in a prospective observational study from October 2020 to May 2021 in Tehran, Iran. Methods Patients who had a record of their 25-hydroxyvitamin D level measured in the previous year before testing positive with COVID-19 were included. Serum 25-hydroxyvitamin D level was measured upon admission in COVID-19 patients. The associations between clinical outcomes of patients and 25-hydroxyvitamin D level were assessed by adjusting for potential confounders and estimating a multivariate logistic regression model. Results The median (interquartile range) age of patients was 60 years (44–74 years), and 53% were male. The median serum 25-hydroxyvitamin D level prior to admission decreased with increasing COVID-19 severity (P=0.009). Similar findings were obtained when comparing median serum 25-hydroxyvitamin D on admission between moderate and severe patients (P=0.014). A univariate logistic regression model showed that vitamin D deficiency prior to COVID-19 was associated with a significant increase in the odds of mortality (odds ratio, 2.01; P=0.041). The multivariate Cox model showed that vitamin D deficiency on admission was associated with a significant increase in risk for mortality (hazard ratio, 2.35; P=0.019). Conclusions: Based on our results, it is likely that deficient vitamin D status is associated with increased mortality in COVID-19 patients. Thus, evaluating vitamin D level in COVID-19 patients is warranted.

Effect of Enhanced External Counterpulsation and Cardiac Rehabilitation on Quality of Life, Plasma Nitric Oxide, Endothelin 1 and High Sensitive CRP in Patients With Coronary Artery Disease: A Pilot Study

Seyed Kazem Shakouri,Zeynab Razavi,Fariba Eslamian,Homayoun Sadeghi-Bazargani,Samad Ghaffari,Arash Babaei-Ghazani 대한재활의학회 2015 Annals of Rehabilitation Medicine Vol.39 No.2

Objective To investigate the effect of enhanced external counterpulsation (EECP) on plasma nitric oxide (NO), Endothelin 1 (ET1), high sensitive C-reactive protein (HSCRP) and quality of life (QoL) in patients with coronary artery disease (CAD).Methods We conducted a pilot randomized clinical trial in order to evaluate plasma NO, ET1, HSCRP and QoL before and after twenty sessions of EECP (group A) and cardiac rehabilitation (CR, group B) in 42 patients with CAD (21 in each group).Results Forty-two patients (33 male and 9 female) were included in the study. The mean age was 58.2±10 years. The mean HSCRP was 1.52±0.7 in the EECP group and it was reduced to 1.27±0.4 after intervention. The reduction in HSCRP was not statistically significant in EECP and CR groups with p=0.33 and p=0.27, respectively. There was not significant improvement of NO, ET1, and QoL in the EECP and CR groups shortly after therapy (p>0.05).Conclusion Although the short-term EECP treatment in CAD patients improved HSCRP, NO, ET1, and QoL compared with the baseline those improvements are not statistically significant. Further studies are necessary with large study groups and more sessions.

Effect of water storage on flexural strength of silorane and methacrylate-based composite resins

Panahandeh, Narges,Torabzadeh, Hassan,Naderi, Hani,Sheikh-Al-Eslamian, Seyedeh Mahsa The Korean Academy of Conservative Dentistry 2017 Restorative Dentistry & Endodontics Vol.42 No.4

Objectives: This study assessed the effect of water storage on the flexural strength (FS) of low shrinkage composites. Materials and Methods: A total of 165 bar-shaped specimens ($2{\times}2{\times}25mm$) were fabricated of 2 low shrinkage composites (Filtek P90 [3M ESPE], GC Kalore [GC International]) and a conventional methacrylate-based composite (Filtek Z250 [3M ESPE]). The specimens were subjected to 3-point bending test at 6 time intervals, namely: immediately after curing, at 24 hours, 1 week, 1 month, 6 months, and 1 year following storage in wet and dry conditions. The FS of the specimens were measured by applying compressive load at a crosshead speed of 1.0 mm/min. Data was analyzed using 3-way analysis of variance (ANOVA) and Tukey's test. Results: Three-way ANOVA revealed significant interactions between time, type of composite, and storage condition (p = 0.001). Tukey's multiple comparison test revealed significant reductions in FS of all composites after 6 months and 1 year of storage in distilled water compared to dry condition. Conclusions: Filtek P90 showed the highest and GC Kalore showed the lowest FS after 1 year storage in distilled water. The immediate high strength of Filtek Z250 significantly decreased at 1 year and its final value was lower than that of Filtek P90.

The Impact of Rigid Cervical Collars on Outcome of Patients Who Underwent Posterior Cervical Laminectomy and Fusion: A Retrospective Comparative Study

Khadivi Masoud,Moghadam Navid,Saghebdoust Sajjad,Khan Furqan Mohammed Yaseen,Eslamian Mohammad,Jouibari Morteza Faghih,Shafizadeh Milad,Moosavi Mersad,Zarei Mohammad,Kordi Ramin,Rostami Mohsen 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.2

Study Design: Retrospective cohort study.Purpose: This study aimed to investigate the cervical collar impact on the functional outcomes of patients after posterior cervical laminectomy and lateral mass screw fixation (PCLF) surgery.Overview of Literature: The safety and possible benefits of implementing rigid cervical collars subsequent to PCLF are insufficiently investigated.Methods: Patients who underwent PCLF and received postoperative cervical collars from 2018 to 2020 were included in this retrospective cohort study. Their data were compared with an age- and sex-matched group of subjects who did not receive collars after PCLF during the same period. Pain intensity (using the Visual Analog Scale), Neck Disability Index, and quality of life (using 36-item Short Form Health Survey) of the patients were compared at baseline, 1, 3, 6, and 12 months postoperatively.Results: A total of 36 patients who received cervical collars after surgery and 40 controls were included. At baseline and 1-month follow-up, there were no differences in pain intensity, functional status, and quality of life between the groups. However, at 3 months postoperatively, the quality of life of the subjects with no orthosis was higher than those who received cervical collars (p =0.01). At 6- and 12-month follow-up, there were no differences between the groups in pain intensity, functional status, and quality of life.Conclusions: No difference in the pain intensity and functional status of patients who used cervical collars and controls was shown in our study. Patients who did not wear cervical collars had a higher quality of life during the 3-month postoperative evaluation. Future prospective, well-controlled studies with longer follow-ups are needed to further investigate the effects of cervical orthosis on the clinical outcome of patients after PCLF.