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      • KCI등재후보

        Awareness of Asbestos and Action Plans for Its Exposure can Help Lives Exposed to Asbestos

        이후장,박은기,Donald Wilson,Engin Tutkun,옥철호 한국산업안전보건공단 산업안전보건연구원 2013 Safety and health at work Vol.4 No.2

        Despite the fact that asbestos is a known carcinogen to humans, it is still used in industrialized countries, especially Asian countries. The global incidence of asbestos-related diseases (ARDs) due to the past use of asbestos, continues to increase, although many countries have adopted a total ban on asbestos use. The implementation of effective strategies to eliminate ARDs is therefore an important challenge in Asia, where asbestos is still mined and consumed. Collaborative efforts and strategies at the local and international levels are vital, in the pursuit toward the elimination of ARDs in this region.

      • KCI등재

        Bactericidal Efficacy of a Disinfectant Composed of Povidone-iodine Against Clostridium Perfringens and Mycobacterium Fortuitum

        차춘남,박은기,조유영,유창열,Engin Tutkun,김석,이후장 한국식품위생안전성학회 2015 한국식품위생안전성학회지 Vol.30 No.1

        Clostridium perfringens (C. perfringens) and Mycobacterium fortuitum (M. fortuitum) are associated with considerable diseases in animals and human. In this study, the disinfection efficacy of a commercial disinfectant composed to povidone-iodine (PVI) was evaluated against C. perfringens and M. fortuitum. A bactericidal efficacy test by broth dilution method was used to determine the lowest effective dilution of the disinfectant following exposure to C. perfringens and M. fortuitum for 30 min at 4°C. The disinfectant and test bacteria were diluted with hard water (HW) or organic matter suspension (OM) according to treatment condition. On HW condition, the bactericidal activity of the disinfectant against C. perfringens and M. fortuitum was 50 and 80 fold dilutions, respectively. On OM condition, the bactericidal activity of the disinfectant against both C. perfringens and M. fortuitum was 15 fold dilutions. As the disinfectant composed to PVI possesses bactericidal efficacy against C. perfringens and M. fortuitum, the disinfectant solution can be used to control the spread of bacterial diseases.

      • KCI등재

        Effects of Feeding a Combination of Probiotics Containing Lactobacillus plantarum and Bacillus Subtilis on Immune Response and Diarrhea Incidence in Post-weaning Piglets

        박은기,유은아,차춘남,Engin Tutkun,김석,이후장 한국임상수의학회 2013 한국임상수의학회지 Vol.30 No.6

        A study investigated the effects of a mixture of Lactobacillus plantarum (L. plantarum) and Bacillus subtilis (B. subtilis) on diarrhea incidence, immune response, and fecal microflora counts in post-weaning piglets. One hundred 28-day-old piglets were randomly assigned to five treatment groups: negative control (NC), free of antibiotics; positive control (PC), 0.03% chlortetracycline; LB 1, a mixture of L. plantarum and B. subtilis (LB) 0.5 kg/ton feed; LB 2, LB 1.0 kg/ton feed; and LB 3, LB 2.0 kg/ton feed. Diarrhea scores for LB 2 and LB 3 from the 2nd week were significantly reduced compared to NC (P < 0.05). In terms of the level of IgG and IFN-γ, all treatment groups were significantly higher than NC (P < 0.05), and the IgG level of LB 3 was significantly higher than that of PC (P < 0.05). Furthermore, fecal lactic acid bacteria (LAB) counts for LB 2 and LB 3 were significantly higher than those of NC and PC (P < 0.05). In addition, fecal Enterobacteriaceae (ENT) counts for PC, LB 2 and LB 3 were significantly lower than those of NC (P < 0.05). Based on the results from this study, it was concluded that a combination of L. plantarum and B. subtilis strains could be used as potential alternatives to antibiotics to prevent diarrhea incidence in piglets.

      • KCI등재

        Bactericidal Efficacy of a Disinfectant Composed of Povidone-iodine Against Clostridium Perfringens and Mycobacterium Fortuitum

        Cha, Chun-Nam,Park, Eun-Kee,Cho, Youyoung,Yoo, Chang-Yeul,Tutkun, Engin,Kim, Suk,Lee, Hu-Jang The Korean Society of Food Hygiene and Safety 2015 한국식품위생안전성학회지 Vol.30 No.1

        Clostridium perfringens (C. perfringens)와 Mycobacterium fortuitum (M. fortuitum)은 동물과 사람에서 심각한 질병과 관련이 있는 세균들로 알려져 있다. 본 연구에서는, povidone-iodine을 주성분으로 하는 소독제의 살균효과를 C. perfringes와 M. fortuitum을 대상으로 평가하였다. 소독제의 살균효과는 배지희석법을 이용하여, 대상 세균들을 $4^{\circ}C$에서 소독제에 30분 동안 노출시킨 다음, 가장 낮은 소독제의 살균 희석배수를 결정하였다. 소독제는 경수와 유기물로 희석하였으며, 경수 조건에서, C. perfringes와 M. fortuitum에 대해 효과적인 소독제 희석배수는 각각 50과 80배이었다. 유기물 조건에서는, C. perfringes와 M. fortuitum에 대해 효과적인 소독제 희석배수는 모두 15배로 나타났다. 이상의 결과로 부터, povidone-iodine을 주성분으로 하는 소독제는 C. perfringes와 M. fortuitum에 대해 살균효과를 갖는 것으로 확인되었으며, C. perfringes와 M. fortuitum에 의한 질병의 확산을 방지하기 위해 사용될 수 있을 것으로 사료된다. Clostridium perfringens (C. perfringens) and Mycobacterium fortuitum (M. fortuitum) are associated with considerable diseases in animals and human. In this study, the disinfection efficacy of a commercial disinfectant composed to povidone-iodine (PVI) was evaluated against C. perfringens and M. fortuitum. A bactericidal efficacy test by broth dilution method was used to determine the lowest effective dilution of the disinfectant following exposure to C. perfringens and M. fortuitum for 30 min at $4^{\circ}C$. The disinfectant and test bacteria were diluted with hard water (HW) or organic matter suspension (OM) according to treatment condition. On HW condition, the bactericidal activity of the disinfectant against C. perfringens and M. fortuitum was 50 and 80 fold dilutions, respectively. On OM condition, the bactericidal activity of the disinfectant against both C. perfringens and M. fortuitum was 15 fold dilutions. As the disinfectant composed to PVI possesses bactericidal efficacy against C. perfringens and M. fortuitum, the disinfectant solution can be used to control the spread of bacterial diseases.

      • SCOPUSKCI등재

        Awareness of Asbestos and Action Plans for Its Exposure can Help Lives Exposed to Asbestos

        Lee, Hu-Jang,Park, Eun-Kee,Wilson, Donald,Tutkun, Engin,Oak, Chulho Occupational Safety and Health Research Institute 2013 Safety and health at work Vol.4 No.2

        Despite the fact that asbestos is a known carcinogen to humans, it is still used in industrialized countries, especially Asian countries. The global incidence of asbestos-related diseases (ARDs) due to the past use of asbestos, continues to increase, although many countries have adopted a total ban on asbestos use. The implementation of effective strategies to eliminate ARDs is therefore an important challenge in Asia, where asbestos is still mined and consumed. Collaborative efforts and strategies at the local and international levels are vital, in the pursuit toward the elimination of ARDs in this region.

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