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Abdalla El Azab,Ahmed Abd Elbary,Aly El Faqeh M. Okasha,Hatem Aboulkassem,Ashraf Saad Zaghloul,Riham Mohamed Karkeet,Ibrahim Abdelrahman 대한비뇨의학회 2023 Investigative and Clinical Urology Vol.64 No.6
Purpose: The clinical effect of neoadjuvant intravesical instillation of chemotherapy immediately before transurethral resection of bladder tumors (TURBT) has been a subject of recent research. The aim of this study was to assess the effect of immediate neoadjuvant electromotive instillation of mitomycin C before transurethral resection for patients with non-muscle-invasive urothelial bladder cancer. Materials and Methods: Our study was a randomized clinical trial carried out on 50 patients diagnosed with non-muscle-invasive urothelial bladder cancer. Patients were classified into two groups: Group I consisted of 25 patients who received neoadjuvant electromotive drug administration of mitomycin C before TURBT and intravesical bacille Calmette–Guerin (BCG) per week for 6 weeks; Group II consisted of 25 patients who were treated with TURBT followed by intravesical BCG per week for 6 weeks alone (standard of care). Patients were followed up at 3, 6, 12, and 18 months by cystoscopy. Results: Patients who received neoadjuvant electromotive drug administration of mitomycin C before TURBT in combination with BCG had a low recurrence rate compared with those who received BCG alone (12.0% vs. 48.0%, respectively; p=0.012) and a longer disease-free interval (88.0% vs. 52.0%, respectively; p=0.012). Four patients developed progression to muscle-invasive disease (16.0%) in the BCG alone group. However, this difference was not statistically significant (p=0.516). Regarding adverse effects, there were no statistically significant differences between the groups. Conclusions: Neoadjuvant intravesical electromotive drug administration of mitomycin C before TURBT is safe; reduces recurrence rates and enhances the disease-free interval compared with TURBT followed by BCG alone.
Double Fuzzy Preproximity Spaces
Ahmed M. Zahran,M. Azab Abd-Allah,Kamal El- Saady,Abd El-Nasser G. Abd El-Rahman 한국지능시스템학회 2007 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.7 No.4
In this paper, we introduce the concept of double fuzzy preproximity spaces as a generalization of a fuzzy preproximity spaces and investigate some of their properties. Also we study the relationships between double fuzzy preproximity spaces, double fuzzy topological spaces and double fuzzy closure spaces. In addition to this was the introduction of the concept of double fuzzy neighborhood system and has been studying the connection with double fuzzy preproximity, which resulted in the definition of the concept double fuzzy preproximal neighborhood.
Double Fuzzy Preproximity Spaces
Zahran, Ahmed M.,Abd-Allah, M. Azab,El-Saady, Kamal,El-Rahman, Abd El-Nasser G. Abd Korean Institute of Intelligent Systems 2007 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.7 No.4
In this paper, we introduce the concept of double fuzzy preproximity spaces as a generalization of a fuzzy preproximity spaces and investigate some of their properties. Also we study the relationships between double fuzzy preproximity spaces, double fuzzy topological spaces and double fuzzy closure spaces. In addition to this was the introduction of the concept of double fuzzy neighborhood system and has been studying the connection with double fuzzy preproximity, which resulted in the definition of the concept double fuzzy preproximal neighborhood.
El-Sikaily Amany,Helal Mohamed,Nsonwu-Anyanwu Augusta Chinyere,Azab Hossam,Abd ElMoneim Neveen,Farahat Eman Othman Salem,Saad Aziza 한국독성학회 2023 Toxicological Research Vol.39 No.3
Chronic exposure to Poly aromatic hydrocarbons (PAHs) may be associated with adverse pregnancy outcomes. Disruption of hormonal and redox balance by toxic PAH metabolites may interfere with successful pregnancy leading to miscarriage. The association of exposure to PAH contaminated mussel via the dietary route with perturbations in reproductive hormones, biomarkers of oxidative stress, and PAH metabolites were assessed in women with recurrent pregnancy loss (RPL). Furthermore, an analysis of the concentration of PAHs in environmentally relevant bivalve animals was performed to preliminary get insights into the levels of these pollutants in the environment. Seventy-six women (20–35 years) were categorized into 18 fertile women without RPL (control), and Groups I, II, and III comprising 24, 18, and 16 women with RPL (2, 3, and > 3 abortions respectively) were studied. Whole blood samples were collected for the estimation of malondialdehyde (MDA), catalase, reduced glutathione (GSH), glutathione-S-transferase (GST), progesterone (P4), follicle-stimulating hormone (FSH), benzo[a]pyren-7,8-dihydrodiol-9,10-epoxide-albumin adduct (BPDE-albumin) and urine for α-naphthol and β-naphthol. Two species of mussel Donax trunculus and Andar aduloii samples were collected for the estimation of 16 priority PAHs. The concentration of PAHs exceeding the maximum limits was observed in the two species of mussels studied. Higher levels of BPDE-albumin, MDA, GST, α and β-naphthol and lower GSH, catalase, FSH, and P4 were observed in women with RPL (Groups I-III) compared to controls (p = < 0.001). Negative associations were observed between BPDE-albumin and catalase (r = − 0.276, p = 0.036), and GSH (r = − 0.331, p = − 0.011) only in women with RPL. Collectively, our findings indicate a possible association of chronic PAH accumulation with recurrent pregnancy loss in women.
A. M. Zahran,M. Azab Abd-Allah,A. G. Abd El-Rahman 한국지능시스템학회 2006 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.6 No.3
In this paper, we introduce the concepts of r-fuzzy feebly open and r-fuzzy feebly closed sets in ?ostak's fuzzy topological spaces and by using them, we explain the notions of r-fuzzy F-closed spaces. Also, we give some characterization of r-fuzzy F-closedness in terms of fuzzy filter basis and r-fuzzy feebly-θ-cluster points.
SPLINE DIFFERENCE SCHEME FOR TWO-PARAMETER SINGULARLY PERTURBED PARTIAL DIFFERENTIAL EQUATIONS
Zahra, W.K.,El-Azab, M.S.,Mhlawy, Ashraf M. El The Korean Society for Computational and Applied M 2014 Journal of applied mathematics & informatics Vol.32 No.1
In this paper, we construct a numerical method to solve singularly perturbed one-dimensional parabolic convection-diffusion problems. We use Euler method with uniform step size for temporal discretization and exponential-spline scheme on spatial uniform mesh of Shishkin type for full discretization. We show that the resulting method is uniformly convergent with respect to diffusion parameter. An extensive amount of analysis has been carried out to prove the uniform convergence with respect to the singular perturbation parameter. The obtained numerical results show that the method is efficient, stable and reliable for solving convection-diffusion problem accurately even involving diffusion parameter.
Theoretical Investigation of 6,8He Halo Nuclei by Using Microscopic Optical Potentials
Wedad R. Alharbi,Awad A. Ibraheem,M. El-Azab Farid 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.5
Recently measured data for elastic scattering angular distributions of 6,8He projectiles on a 65Cu target at three energies above the Coulomb barrier (19.9, 22.6 and 30.6 MeV) have been investigated in the framework of the optical model potential. The real parts are microscopically calculated with the Reid M3Y effective nucleon-nucleon interaction by using the double folding approach. Results comparable to the experimental data were obtained using two different forms of the imaginary part. The total reaction cross sections were successfully reproduced using the extracted potentials.
Spline difference scheme for two-parameter singularly perturbed Partial differential equations
W. K. Zahra,M. S. El-Azab,Ashraf M. El Mhlawy 한국전산응용수학회 2014 Journal of applied mathematics & informatics Vol.32 No.1
In this paper, we construct a numerical method to solve singularly perturbed one-dimensional parabolic convection–iffusion problems. We use Euler method with uniform step size for temporal discretization and exponential-spline scheme on spatial uniform mesh of Shishkin type for full discretization. We show that the resulting method is uniformly convergent with respect to diffusion parameter. An extensive amount of analysis has been carried out to prove the uniform convergence with respect to the singular perturbation parameter. The obtained numerical results show that the method is efficient, stable and reliable for solving convection–iffusion problem accurately even involving diffusion parameter.
Zahran A. M.,Abd-Allah M. Azab,El-Rahman A. G. Abd Korean Institute of Intelligent Systems 2006 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.6 No.3
In this paper, we introduce the concepts of ${\gamma}$-fuzzy feebly open and ${\gamma}$-fuzzy feebly closed sets in Sostak's fuzzy topological spaces and by using them, we explain the notions of ${\gamma}$-fuzzy F-closed spaces. Also, we give some characterization of ${\gamma}$-fuzzy F-closedness in terms of fuzzy filterbasis and ${\gamma}$-fuzzy feebly-${\theta}$-cluster points.