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Ahmed E. Abdel-Mobdy,Marwa S. Khattab,Ebtesam A. Mahmoud,Eman R. Mohamed,Emam A. Abdel-Rahim 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.1
Lifestyle and diet preferences are primarilyresponsible for developing type 2 diabetes. In this study,okara was manufactured into okara whey crackers (OWC)to investigate its dietary role in controlling diabetes instreptozotocin-diabetic rats with and without a high-fatdiet. Forty-eight rats were divided into eight groups. G1–G4 were nondiabetic and fed a basal diet, a basal diet with30% crackers, high fat diet, and a high-fat diet with 30%crackers, respectively. G5–G8 were diabetic groups thatreceived similar diets as previous groups. Blood glucose,liver function, lipid pattern, pancreas and liverhistopathology, and insulin immunohistochemistry wereperformed. OWC improved measured parameters andhistopathology of the liver and pancreas in diabetic rats. The area % of positive insulin cells was increased in G6(5.20%) and G8 rats (2.83%) fed OWC compared to diabeticrats (1.17%). In conclusion, the use of 30% OWC in asemi-modified diet has controlled the hyperglycemia andhyperlipidemia associated with diabetes.