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      • KCI등재후보

        Prognostic Factors for Well Differentiated Thyroid Cancer in an Endemic Area

        A.K. Sarda,Shweta Aggarwal,Durgatosh Pandey,Gagan Gautam 대한갑상선-내분비외과학회 2002 The Koreran journal of Endocrine Surgery Vol.2 No.1

        A retrospective analysis of 215 differentiated thyroid cancers was undertaken to identify the various prognostic variables. There were 132 papillary and 83 follicular cancers; both histologic types occurred at an earlier age with a male to female ratio of 1:1. 1. There was a significant difference in the size of the primary tumours; 60/132 of papillary and 30/83 of follicular cancers were early TO-2 lesions and 20 papillary and 24 follicular cancers were advanced T3 lesions. Age did not affect the size of the primary tumour. Regional lymph node and pulmonary metastasis was common in both types of cancer while distant metastases occurred more frequently in follicular cancers (P<0.005). Following surgery, contralateral lobe recurrence in the remaining lobe was more common in follicular cancers while loco-regional recurrence after near-total thyroidectomy was more frequent in the papillary cancer group (P>0.05). Mortality in 26/132 papillary and 28/83 follicular cancer patients was high in both groups but significantly higher in follicular cancers (P<0.05). Although amongst papillary cancers mortality was higher in patients above 40 years of age (P<0.05), age did not affect survival in patients with follicular cancers. Sex did not affect survival in either group. The extent of the disease at presentation was found to be the most important determinant of survival with mortality significantly higher in T3N3M1 lesions (P<0.001). (Korean J Endocrine Surg 2002;2: 37-41)

      • Laparoscopic Total Colectomy with Complete Mesocolic Excision and Central vascular ligation: Illustrative step by step approach

        Swapnil Patel,Sriniket Raghavan,Amar Prem,Mayank Tripathi,Saumya Chopra,Durgatosh Pandey 대한종양외과학회 2021 대한임상종양학회 학술대회지 Vol.2021 No.6

        Background/Aims Laparoscopic approach for total colectomy is acceptable ontologically if executed with a complete mesocolic excision and central vascular ligation to ensure radical D3 lymphadenectomy. Methods This is an illustrative video vignette showing a step by step approach to total colectomy with complete mesocolic excision with central vascular ligation. Our patient was a 45yr gentleman with adenocarcinoma of the transverse colon extending to splenic flexure and descending colon with synchronous polyps in right colon on colonoscopy. Staging computed tomography scan did not show any distant metastases. Results Total colectomy was done using laparoscopic approach with a complete mesocolic excision. Stapled ileo-rectal anastomosis was performed. Blood loss was 200mL and intra-operative period was uneventful. Post-operative period was uneventful and patient was discharged on day 6. Final histopathology revealed a moderately differentiated adenocarcinoma of transverse colon and left colon (pT3N1, 0/56 nodes) with dysplastic polyps in right colon. Patient was referred to Medical Oncology for adjuvant chemotherapy. Conclusions This video vignette highlights step by step conduct of a technically challenging procedure using laparoscopy while ensuring oncological adequacy.

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