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      • SCIEKCI등재

        Regulation of Pathogenesis by Light in Cercospora zeae-maydis: An Updated Perspective

        Kim, Hun,Ridenour, John B.,Dunkle, Larry D.,Bluhm, Burton H. The Korean Society of Plant Pathology 2011 Plant Pathology Journal Vol.27 No.2

        The fungal genus Cercospora is one of the most ubiquitous groups of plant pathogenic fungi, and gray leaf spot caused by C. zeae-maydis is one of the most widespread and damaging foliar diseases of maize in the world. While light has been implicated as a critical environmental regulator of pathogenesis in C. zeae-maydis, the relationship between light and the development of disease is not fully understood. Recent discoveries have provided new insights into how light influences pathogenesis and morphogenesis in C. zeae-maydis, particularly at the molecular level. This review is focused on integrating old and new information to provide an updated perspective of how light influences pathogenesis, and provides a working model to explain some of the underlying molecular mechanisms. Ultimately, a thorough molecular-level understanding of how light regulates pathogenesis will augment efforts to manage gray leaf spot by improving host resistance and disease management strategies.

      • KCI등재

        Correlates of Worry Over Time Among the Oldest-Old

        전해숙(Hae-Sook Jeon),Ruth E. Dunkle 한국노년학회 2006 한국노년학 Vol.26 No.2

        초고령노인들에 대한 연구의 부족으로 초고령노인들의 삶, 특히 그들이 일상생활에서 경험하는 걱정거리에 대해 알려진 것은 거의 없다. 본 연구는 (1) 초고령노인의 걱정거리와 신체적, 심리적, 사회적 요소와의 관계에 대해 살펴보고 (2) 이러한 관계가 시간이 지남에 따라 어떻게 변화하는지에 대해 살펴보고자 한다. 1986년에 초고령노인의 건강과 well-being 의 다양한 측면을 조사하기 위해 미국 중서부의 지역사회에 거주하는85세 이상된 초고령노인들을 대상으로 4번의 후속 면접조사(follow-up interview)가 이루어졌다(1986-1995). 본 연구 논문은 Wave 1 부터 Wave 5까지 살아남아서 참석할 수 있었던 23명의 노인들을 대상으로 자료를 분석하였다(Waves 1, 4, 5). 결과는 초고령노인의 걱정과 우울증이 시간이 지남에 따라 증가한 반면에, 예상대로 신체적 요소(ADLs와 IADLs)는 감소하였음을 보여준다. 모든 wave에서 걱정거리는 우울증과 정적인 관계에 있었다. 한편 Wave 1과 4에서는 걱정거리는 신체적 건강과 유의미한 부정적 관계에 있었는데 반해, Wave 5에서는 걱정거리가 자기 통제감(sense of mastery)과 유의미한 부정적 상관관계가 있는 것으로 나타났다. Wave에 따른 서로 다른 발견이 시사하는 바는 초고령노인이 조금이라도 젊었을 때에는 신체적인 건강이, 나이가 더 많이 들어서는 자기통제감이 걱정과 더 연관되어 있다는 것으로, 나이가 들수록 자기 통제감(sense of mastery)이 중요하다는 것을 암시한다. Little is known about the lives of those who are the oldest-old, in particular, the worries they experience everyday. This study aims to explore the relationships between worries and physical, psychological, and social factors as well as changes in these relationships over time. A convenience sample of community dwelling elders over age 85 was recruited to examine various aspects of health and well-being over 9 years (1986-1995). This paper reports on the survivors (n=23) across three time points, Waves 1, 4, and 5. The findings showed that worry and depression among the oldest-old significantly increased over time, and ADLs and IADLs grew significantly worse. At Waves 1 and 4, a higher level of worry was correlated with a higher level of depressive symptoms and poorer health. At Wave 5 the findings showed that only psychological factors (e.g., lower sense of mastery and higher level of depression) were associated with a higher level of worry.

      • KCI등재

        Regulation of Pathogenesis by Light in Cercospora zeae-maydis: An Updated Perspective

        김헌,Burton H. Bluhm,John B. Ridenour,Larry D. Dunkle 한국식물병리학회 2011 Plant Pathology Journal Vol.27 No.2

        The fungal genus Cercospora is one of the most ubiquitous groups of plant pathogenic fungi, and gray leaf spot caused by C. zeae-maydis is one of the most widespread and damaging foliar diseases of maize in the world. While light has been implicated as a critical environmental regulator of pathogenesis in C. zeae-maydis, the relationship between light and the development of disease is not fully understood. Recent discoveries have provided new insights into how light influences pathogenesis and morphogenesis in C. zeae-maydis, particularly at the molecular level. This review is focused on integrating old and new information to provide an updated perspective of how light influences pathogenesis,and provides a working model to explain some of the underlying molecular mechanisms. Ultimately, a thorough molecular-level understanding of how light regulates pathogenesis will augment efforts to manage gray leaf spot by improving host resistance and disease management strategies.

      • KCI등재

        Why Don’t Cancer Survivors Quit Smoking? An Evaluation of Readiness for Smoking Cessation in Cancer Survivors

        Melissa A. Little,Robert C. Klesges,Zoran Bursac,Jon O. Ebbert,Jennifer P. Halbert,Andrew N. Dunkle,Lauren Colvin,Patricia J. Goedecke,Benny Weksler 대한암예방학회 2018 Journal of cancer prevention Vol.23 No.1

        Background: Cancer survivors have a high rate of participation in cigarette-smoking cessation programs but their smoking-abstinence rates remain low. In the current study, we evaluated the readiness to quit smoking in a cancer-survivor population. Methods: Cross-sectional data survey conducted among 112 adult cancer survivors who smoked cigarettes in Tennessee. Analyses were conducted using a two-sample t-test, χ2 test, Fishers Exact test, and multivariable logistic regression with smoker’s readiness to quit as the dependent variable. We operationally defined a smoker not ready to quit as anyone interested in quitting smoking beyond the next 6 months or longer (or not at all), as compared to those that are ready to quit within the next 6 months. Results: Thirty-three percent of participants displayed a readiness to quit smoking in the next 30 days. Smokers ready to quit were more likely to display high confidence in their ability to quit (OR = 4.6; 95% CI, 2.1-9.7; P < 0.0001) than those not ready to quit. Those ready to quit were nearly five times more likely to believe smoking contributed to their cancer diagnosis (OR = 4.9; 95% CI, 1.1-22.6; P = 0.0432). Those ready to quit were also much more likely to attempt smoking cessation when diagnosed with cancer (OR = 8.9; 95% CI, 1.8-44.3; P = 0.0076) than smokers not ready to quit. Finally, those ready to quit were more likely to endorse smoking more in the morning than other times of the day, compared to those not ready to quit (OR = 7.9; 95% CI, 1.5-42,3; P = 0.0148), which increased odds of readiness to quit within the next 6 months. Conclusions: Despite high participation in smoking-cessation programs for cancer survivors, only one-third of participants were ready to quit. Future research is needed to develop programs targeting effective strategies promoting smoking cessation among cancer survivors who are both ready and not ready to quit smoking. (J Cancer Prev 2018;23:44-50)

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