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      • KCI등재

        수출입 컨테이너 장치장 배정을 위한 소프트웨어의 개발

        김갑환,김홍배,홍봉희,김기영,배종욱,최진오,김두열,이영기,박영만,박강태,손행대 한국경영과학회 1995 經營 科學 Vol.12 No.3

        The Pusan Container Terminal faces a rapid increase in berthing time of container ships as well as in waiting time of external trucks, which is due to an absolute lack of yard space. This research is focused on the development of a decision support system for the planning of the container terminal yard assignment so that the yard space would be utilized most effectively. Efforts should be given to the reasonable assignment of the yard storage and the dynamic adaptation to the ever changing environment. The software introduced here is based o the know-how of the field exports and its framework takes the approach of the hierarchical decision making.

      • KCI등재

        허혈 및 재관류후 흰쥐 앞정강근과 가자미근에서 나타나는 미세구조와 SOD 활성의 변화

        백두진,안동춘,황규성,김혜주,박철홍,정호삼,조근열 대한체질인류학회 1999 해부·생물인류학 (Anat Biol Anthropol) Vol.12 No.2

        에너지 획득방법, 당원의 분포, 모세혈관의 분포 및 미세구조의 차이가 나는 백색근육섬유와 적색근육섬유에서 허혈시간에 따라 나타나는 미세구조의 변화와 SOD의 활성변동을 비교 관찰하여 다음과 같은 결과를 얻었다. 1. 앞정강근에서는 2시간 허혈시 사립체에서 바탕질의 전자밀도가 감소하고 사립체능선이 팽대하였고, 재관류 24시간 경과시에는 근육원섬유사이의 거리가 멀어지고 근육세포질세망의 수조와 종말수조가 팽대하였으며 재관류 72시간 경과시에는 정상대조군과 유사한 소견이 나타났다. 2. 가자미근에서 2시간 허혈시 사립체에서는 사렵체바탕질의 전자밀도가 감소하였으며, 재관류 24 시간 경과시는 근육세포질세망의 수조가 팽대하였고, 재관류 72시간 경과시에는 정상대조군과 유사하였다. 3. 4시간 및 6시간 허혈시 미세구조의 변화는 허혈시간과 재관류 시간경과에 따라 심해져 앞정강근에서는 사립체에서 바탕질의 전자밀도가 감소하고 사렵체능선은 불분명하고 소용돌이소체가 나타났으며 근육원섬유 용해와 곤육원섬유괴사가 관찰되었다. 가자미근에서는 근육원섬유에서 근육미세섬유의 배열과 끝가로막이 불규칙해지고 근육세포질세망의 수조가 팽대하였으며 근육원섬유용해가 나타났다. 4. 앞정강근에서 Cu, Zn-및 Mn-SOD 활성은 미약한 흑은 약한 양성반응을 나타내었고, 가자미근에서는 Cu, Zn-SOD는 미약한 양성반응을, Mn-SOD 는 미약한 혹은 약한 양성반응을 나타내었다. 허혈후 Cu, Zn- 및 Mn-SOD 의 활성은 허혈시간이 길수록 더욱 증가하였다. 5. Cu, Zn- 및 Mn-SOD 활성은 2시간 허혈 및 재관류 24 시간 경과시 약간 증가하였으며 72시간 경과시에는 앞정강근과 가자미근에서 정상대조군과 유사하게 나타났다. 6. 4시간 및 6시간 허혈 및 재관류후 두 근육에서 Cu, Zn- 및 Mn-SOD활성은 증가하였다. 두 근육에서 Mn-SOD의 활성변동은 유사하였으나 Cu, Zn- Mn-SOD의 활성증가는 앞정강근보다 가자미근에서 크게 나타났다. 이상의 결과를 종합하면 허혈 및 재관류 손상은 허혈시간과 재관류시간 경과에 따라 심하게 나타났고 가자미근보다 앞정강근에서 심하게 나타났으며, 손상의 차이는 두 근육에서 나타나는 SOD활성변동과 깊은 연관이 있는 것으로 생각된다. Skeletal muscles are known to have tolerance to ischemia, but a prolonged ischemia can cause damage to muscular tissues. The ischemia-reperfusion injury results from the oxygen free radicals released by leucocytes and formed by the reaction of hypoxanthine and xanthine oxidase. Superoxide dismutase (SOD), one of major antioxidant enzymes occurring in the various tissues of the body metabolizes or scarvanges the oxygen free radicals. Although many studies reported difference in tolerance to ischemia and reperfusion between white and red muscles, some other investigators failed in finding such difference. The present study was performed to examine effects of graded periods of ischemia and reperfusion on the cellular ultrastructure and activity of SOD in white and red muscles. The Sprague-Dawley rats (200~250 g) were used as experimental animals. Under pentobarbita] (50 mg/kg IP) anesthesia, incision was made on lower abdomen and left common iliac artery was occluded by means of a vascular clamp for 2, 4 and 6 hour (hrs). Thereafter, the superficial portion of mid-belly of anterior tibial muscle and soleus muscles were excised at 0, 24 and 72 hrs after onset of reperfusion. The specimens were sectioned into slices, 2 mm in length, 1 mm in width and thickness. Some specimens were prepared for electron microscopic observation and others for determination of SOD activity by using antihuman CU, Zn- and Mn-SOD antibodies. The results obtained were as follows. 1. In anterior tibial muscle, areas with loose electron-density and dilated cristae were observed in the mitochondria immediately after 2 hrs of ischemia, while widened intermyofibrillar spaces and dilated cisternae of sarcoplasmic reticulum were seen after 2 hrs and 24 hrs reperfusion. When subjected to 2 hrs ischemia and 72 hrs reperfusion, no significant change was found in the cellular ultrastructure. 2. In soleus muscle, electron density was loose in the matrix of mitochondria immediately after 2 hrs of ischemia, while cisternae of sarcoplasmic reticulum were dilalated after 2 hrs of ischemia and 24 hrs reperfusion. Following 2 hrs of ischemia and 72 hrs repeifusion, the electron microscopic findings were similar to those of normal rats. 3. The changes in cellular ultrastructure were more prominent in both the 4 hrs and 6 hrs ischemia groups, in which degree of ultrastructural changes were proportional to duration of reperfusion. 4. In anterior tibial muscle, trace or weak immunoreactivities of Cu, Zn- and Mn-SOD were seen, whereas trace immunoreactivity of Cu, Zn-SOD and trace or weak immunoreactivity of Mn-SOD were observed in soleus muscle. 5. The immunoreactivities of CU, Zn- and Mn-SOD were not altered in 2 hrs ischemic and 72 hrs reperfused group, while they were increased slightly in 2 hrs ischemic and 24 hrs reperfused group. 6. In both muscles, the activity of SOD increased following 4 hrs or 6 hrs ischemia and 24 hrs or 72 hrs reperfusion. The changes in immunoreactivity of Mn-SOD were not different between two muscles, whereas immunoreactivity of Cu, Zn-SOD were higher in anterior tibial muscle. Consequently, it is suggested that significant ischemia reperfusion injuries are produced after 4 ~ 6 hrs ishemia followed by 24 hrs or 72 hrs reperfusion, that anterior tibial muscle is more susceptible to ischemic reperfusion injury and that the ischemic-reperfusion injury is closely related with activity of SOD.

      • KCI등재후보

        인터페이스 회로를 적용한 디젤기관의 배출가스특성에 관한 실험적 연구

        한영출,김대열,백두성 한국공작기계학회 2003 한국생산제조학회지 Vol.12 No.6

        In order to collect the engine performance data and determine optimum engine conditions, engine performance test based on interface unit were tested. This paper was carried out that engine' performance was developed using interface unit between personal computer and diesel engine. The results of the study are summarized as follows: Interface unit was developed. By using PAL, Simulation was carried in order to logic's inspection. From this test, NOx were decreased, otherwise PM were increased. By using EGR system, PM were increased by twice in the high load ranges, it was not seen to come into effect in the low load ranges. This system was tested D13 mode, the results were decreased more than 50% in the NOx emission.

      • 농작물 해충 및 진균류 방제를 위한 방선균의 분리 및 동정

        이은정,강경돈,황교열,김두호,김신덕,성수일 한국잠사학회 1998 한국잠사곤충학회지 Vol.40 No.1

        Twenty seven out of ca. 5,000 actinomycete strains, which were isolated from soil collected throughout the country, showed antimicrobial effects against fungi, Rhizopus stronifer (ATCC6227a), Rhizoctonia solani (KCCM 11271) and yeast, Candida albicans(ATCC10231). From these antifungal microorganisms, we further selected seven strains which seemed to produce insecticidal substances with in vivo test, using silkworm, Bombyx mori and beet armyworm, Spodoptera exigua. Morphological and biochemical experiments revealed that three strains out of seven were streptomyces. Further investigations on the physical and chemical properties of these antifungal and insecticidal substances are now in progress.

      • KCI등재
      • KCI등재

        Clinical outcomes of two-stage revision for chronic periprosthetic joint infection of the knee: culture-negative versus culture-positive

        Kim Chang-Wan,이창락,박대현,Kim Doo-Yeol,Kim Jeong-Woo 대한슬관절학회 2021 대한슬관절학회지 Vol.33 No.-

        The effect of negative culture on the treatment outcomes of chronic periprosthetic joint infection (PJI) is still controversial. The purpose of this study is to evaluate whether the outcomes of two-stage revision in culture-negative chronic PJI differ from those in culture-positive PJI.The patients who received two-stage revisions due to chronic PJI during the period between 2007 and 2017 were retrospectively reviewed. The culture-negative and culture-positive PJI group included 57 cases and 79 cases, respectively. The demographic data, as well as reoperation, mortality, reinfection, and failure rates of each group were evaluated. There was a significant difference in reoperation rate between the two groups for the period from the first-stage surgery to the second-stage revision arthroplasty ( p = 0.045). The reoperation rate of the culture-positive group was 25.3% (20/79) whereas that of the culture-negative group was 10.5% (6/57). Among the 136 PJI cases, 97 cases (71.3%) received reimplantation surgery (culture-negative group, 43 cases; culture-positive group, 54 cases). No significant difference was noted between the culture-negative and culture-positive groups with respect to the number of cases that did not undergo reimplantation surgery and the reoperation, reinfection, mortality, and failure rates after two-stage surgery ( p > 0.05, all parameters). The culture outcome had no significant effect on the outcome of the two-stage revision in patients with chronic PJI. The reoperation rate after first-stage surgery was significantly higher in the culture-positive group, but the overall failure rate did not significantly differ in both the groups. The presence of a negative culture might be a good prognostic factor for chronic PJI.

      • KCI등재

        Factors affecting range of motion following two-stage revision arthroplasty for chronic periprosthetic knee infection

        ( Doo-yeol Kim ),( Young-chae Seo ),( Chang-wan Kim ),( Chang-rack Lee ),( Soo-hwan Jung ) 대한슬관절학회 2022 대한슬관절학회지 Vol.34 No.-

        Introduction: The purpose of this study was to evaluate factors that affect range of motion (ROM) following twostage revision arthroplasty as a treatment for chronic periprosthetic knee infection. Materials and methods: A total of 98 patients diagnosed with chronic periprosthetic joint infection (PJI) following primary total knee arthroplasty between January 2009 and December 2019 and then underwent two-stage revision arthroplasty were reviewed retrospectively. Multiple regression analysis was performed to evaluate the factors that affect ROM after two-stage revision arthroplasty. ROM after two-stage revision arthroplasty was used as a dependent variable, while age at the time of surgery, ROM at PJI diagnosis, ROM after the first-stage surgery, the interval between the first-stage surgery and the second-stage surgery, whether a re-operation was performed before the second-stage surgery, culture results (culture negative or culture positive), and body mass index (BMI) were used as independent variables. Results: Multiple regression analysis (R<sup>2</sup> = 0.843) revealed that among the independent variables, ROM (β = 0.604, P < 0.001) after the first-stage surgery, whether a re-operation was performed before the second-stage surgery (β = - 8.847, P < 0.001), the interval between the first-stage surgery and the second-stage surgery (β = - 0.778, P = 0.003), and BMI (β = - 0.698, P = 0.041) were associated with ROM after two-stage revision arthroplasty, the dependent variable. Conclusions: In two-stage revision arthroplasty for chronic periprosthetic knee infection, ROM after the first-stage surgery, whether a re-operation was performed before the second-stage surgery, the interval between the first-stage surgery and the second-stage surgery, and BMI were found to be factors that were associated with ROM after twostage revision arthroplasty.

      • 유기용제 노출 근로자들의 신경학적 검사에 관한 연구

        김정일,김두희,김상우,박태혁,정갑열,김준연 동아대학교 부설 산업의학연구소 1999 산업의학연구소 논총 Vol.- No.4

        Objectives : Authors performed this study to investigate the early effect of organic solvents exposure on nervous systems and the relationship between effects central and peripheral nervous systems. Methods : We measured the air solvents levels and the urinary hippuric acid level of the workers exposed to toluene. We selected 30 workers exposed to organic solvents as the exposed guoup and 30 workers not to exposed to organic solvents as the non-exposed guoup. They were examined with neurabehavior core test batteries (NCTB) and nerve conduction velocity (NCV). Results ; (1) The NCTB showed that the exposed ghoup had lower score than the non-exposed ghoup in the digit span, preferred hand of Santa Ana dexterity and pursuit aiming (p<0.05), but simple reaction time, Digit Symbol, and Benton Visual Retention showed no statistical differences between the exposed and the non-exposed groups. (2) Teh NCV showed that the conduction velocity of median nerve decreased in the exposed group (p<0.05), however, those of ulnar nerve, posterior tibial nerve, peroneal nerve and sural nerve didn't show the differences. The amplitude also showed no differences. (3) There was little correlation between NCV and NCTB.

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