족과관절염좌 환자에 대한 동씨침법과 일반침법의 효과에 대한 비교 연구

안호진,정동화,황규선,윤기붕,김태우,문장혁,백종엽,이상무,Ahn, Ho-jin,Jeong, Dong-hwa,Hwang, Kyu-seon,Yoon, Ki-bung,Kim, Tae-woo,Moon, Jang-huyk,Baek, Jong-yeob,Lee, Sang-moo 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective: The purpose of this study is to compare the effects of Dong-si acupuncture therapy and General acupuncture therapy for the patients with acute ankle sprain. Methods : This study has been carried out for 60 cases of ankle sprain patients who have visited Dong-Seo Oriental medical Hospital from May 1, 2002 to September 30, 2002. We have treated 30 cases of them by Dong-si acupuncture therapy and the other 30 cases by General acupuncture therapy. And we have compared those two group. Results : 1. There was no significant difference at the treatment period and the number of treatment times in comparing two groups. 2. The number of treatment times for good effect is that : Dong-si took $1.57{\pm}0.85$ times and General acupuncture therapy took $2.15{\pm}0.96$ times. And we have found that the effect of Dong-si acupuncture therapy is faster than the other.

요동반도 영성자 고분벽화의 신선신앙

안동준(Ahn, Dong-zoon) 고조선단군학회 2021 고조선단군학 Vol.46 No.-

영성자 고분벽화는 도교미술사에서 최초의 도교벽화로 알려져 있는데, 현재 중국 학계에서는 우화등천을 갈구하는 祖上의 薦度를 주된 내용으로 하는, 한나라 시대의 미신과 참위사상을 반영한 것이라고 주장한다. 그러나 영성자 벽화의 신앙적 요소나 제사의 성격은 후한 말의 도교와 엄연히 다르다. 왜냐하면 도상의 세부 내용을 검토해 보면, 벽화의 실제 내용이 후한 시대의 오두미교가 성립하기 이전에 유행한 신선신앙의 흔적을 보여주고 있기 때문이다. 이 논문에서는 요동반도 남단에 위치한 영성자 고분벽화의 도상적 의미를 재검토하고, 이른바 ‘무덤주인’으로 간주하는 중심인물과 그 주변 인물의 형상을 동왕공 신앙과 관련하여 새롭게 해석했다. 나아가 영성자 고분의 묘실 구조와 벽화의 구성 및 등장인물의 정체와 제사 내용의 성격 등을 고찰하여 단순한 제사 장면으로 간주하지 못하는 독특한 측면이 있다는 사실과, 고분벽화의 내용에서 무덤주인이 동왕공이며 동이계 신선들이 신앙의 대상으로 숭배되었다는 사실을 밝혔다. 또한 이러한 신선신앙이 태일신앙과 관련된 음주문화의 형태로 이루어졌다는 것을 밝혀서 영성자 고분벽화의 제사 성격이 조상 천도를 목적으로 하는 일반인의 제사가 아니라는 점을 지적했다. What is discussed in this paper is a review of the iconographic meaning of Yingchengzi tomb murals located at the southern tip of Liaodong Peninsula. In addition, new interpretations were attempted on questions about existing studies that it refers to various documents and archaeological achievements. In the course of the discussion, the focus was on the central figure regarded as the so-called tomb owner and the shape of the people around him, and various factors related to the belief of Dong-wang-gong (東王公) were considered. In addition, the structure of the burial chamber of Yingchengzi tomb, the composition of the murals, the identity of the characters, and the nature of the ritual contents were reviewed. What was revealed as a result is a unique characteristic that cannot be regarded as a simple ritual scene. In other words, the content is the fact that the tomb owner in Yingchengzi tomb murals is Dong-wang-gong, and at the same time, the eastern origin Immortals were worshiped as an object of faith. In addition, this belief in immortality was formed in the form of drinking culture that is closely related to Tae-il (太一) faith. In other words, the ancestral rituals in Yingchengzi tomb murals is not a simple funeral rituals for the ancestor spirits. Moreover, Yingchengzi tomb itself is not located in the Chinese mainland, but in the Cheng-gu (青丘) area at the southern tip of the Liaodong Peninsula, facing Shandong(山東) across the sea. Taking this into account, the structure of the tomb and what was painted on the murals in Yingchengzi tomb murals are related to the sea exploration activities of the Jinhan(秦漢) period in China. Because it was an attempt to save the immortality. Such a conclusion has important significance. This is because it identifies the nature of immortal belief in the Liaodong Peninsula and provides an archaeological basis for the origin of the cult of immortality.

NGS_SNPAnalyzer: a desktop software supporting genome projects by identifying and visualizing sequence variations from next-generation sequencing data

Dong‑Jun Lee,Taesoo Kwon,Chang‑Kug Kim,Young‑Joo Seol,Dong‑Suk Park,Tae‑Ho Lee,Byung‑Ohg Ahn 한국유전학회 2020 Genes & Genomics Vol.42 No.11

Background Sequence variations such as single nucleotide polymorphisms are markers for genetic diseases and breeding. Therefore, identifying sequence variations is one of the main objectives of several genome projects. Although most genomeproject consortiums provide standard operation procedures for sequence variation detection methods, there may be differencesin the results because of human selection or error. Objective To standardize the procedure for sequence variation detection and help researchers who are not formally trainedin bioinformatics, we developed the NGS_SNPAnalyzer, a desktop software and fully automated graphical pipeline. Methods The NGS_SNPAnalyzer is implemented using JavaFX (version 1.8); therefore, it is not limited to any operatingsystem (OS). The tools employed in the NGS_SNPAnalyzer were compiled on Microsoft Windows (version 7, 10) andUbuntu Linux (version 16.04, 17.0.4). Results The NGS_SNPAnalyzer not only includes the functionalities for variant calling and annotation but also providesquality control, mapping, and filtering details to support all procedures from next-generation sequencing (NGS) data to variantvisualization. It can be executed using pre-set pipelines and options and customized via user-specified options. Additionally,the NGS_SNPAnalyzer provides a user-friendly graphical interface and can be installed on any OS that supports JAVA. Conclusions Although there are several pipelines and visualization tools available for NGS data analysis, we developedthe NGS_SNPAnalyzer to provide the user with an easy-to-use interface. The benchmark test results indicate that theNGS_SNPAnayzer achieves better performance than other open source tools.

낙후 원도심 거주환경의 물리적 기능적 만족도와 심리적 정서적 만족도의 거주기간에 대한 영향력 비교 분석

안동준(Ahn, Dong-Joon),박성용(Park, Sung-Yong) 대한건축학회 2018 대한건축학회논문집 Vol.34 No.7

The goal of this research is to compare influences for living periods between physical functional satisfaction and psychological emotional satisfaction in a ghetto area. The research site is ‘Sujin1 dong’ in Sungnam city which is one of the oldest residential areas in the city. Based on the analysis of the urban contexts for the research site, surveys are conducted to gather the data which are treated by several statistical techniques: ‘Factor analysis’, ‘Reliability Analysis’, ‘Multiple regression analysis’. Through the statistical process, conclusions are drawn as follows. In the ghetto urban area, ①-The higher the psychological emotional satisfaction, the longer the living period, ②-The longer the residence period, the lower the physical and functional satisfaction, ③-The two satisfactions tend to be opposite to each other according to the living period. ④-The psychological emotional satisfaction is more related with living period than the physical and functional satisfaction is.

가축분뇨를 이용한 SCP 생산 균주의 분리 및 균체 단백질 생산

한석균,고유석,안태영,배동훈 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

질소원으로서 계분을 이용하는 균주를 선별하고 계분배지에서 균체의 생육속도가 다른 균주에 비하여 우수한 균주를 분리하였다. 형태·생리학적 특성을 기초로 하여 yeast의 분류 기준과 비교하여 본 균주를 Candida sp.로 동정하였으며 본 균주를 Candida sp. D116으로 명명하였다. Poultry feces extract medium에서 4% 농도의 glucose 첨가가 균체 생육에 효과적이었다. D116 균주를 액체 발효하여 균체생산능, 요산 그리고 가용성 단백질의 변화를 조사하였다. 그 결과 약 60시간이 경과하면 액체 발효 배지내의 거의 모든 가용성 단백질 및 요산의 감소를 보였으며 균체생육은 약 36시간 배양하였을 때 최고조에 도달하였고 그 후에는 점차 감소하는 경향을 보였다. SCP의 대량생산의 결과 50%의 계분혼합 배지와 30℃의 배양 온도에서 36시간 배양하여 균주의 생육수준이 3.8×10^9 CFU/ml 농도의 균체를 생산하였고 200 L의 배양액중 약 870 g-dw의 균체를 얻었으며 생산된 군체의 조단백질 함량은 67%이었다. Production of Single Cell Protein from Poultry Feces. Suk-kyun Han, You-Suk Go, Tae-Young Ahn and Dong-Hoon Bal^1*. Deparment of Microbioligy, College of Natural Sciences, Dankook Univerity, Cheonan 330-714 and Research Center for Molecular Microbiology, Seoul Nationa University, Seoul 151-742, Korea, ^1Department of Food Engineering. College of Engineering, Dankook University, Cheonan 330-714 and Bioproducts Research Center of Yonsei University, Seoul 120-749, Korea - From the soil collected form provincial area of South Korea, a microorganisms which have been shown good growth in the minimal poultry feces extract medium was isolated. Supplement of glucose to the poultry feces extract medium helped the complete degraded during the microbial growth. Maximum cell growth (3.8×10^9 CFU/ml) obtained at 36 hours of incubation after inoculation. Uric acid was degraded faster in minimal medium that in the glucose complement medium. VFA (volatile fatty acid), which are known as major compounds of poultry feces odor, were almost removed from the minimal poultry feces extract medium. Glucose supplement to the minimal medium enhanced the growth of microbial cells. Addition of 4% of glucose and 4% of neopeptone to the minimal poultry feces extract medium helped the maximal growth of cells.

녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

서울 서남부지역 노인 인구에서 비만증 유병률과 고지혈증과의 상관성

최경묵,조영직,김경오,김동림,김난희,백세현,안정천,서홍석,오동주,최동섭 대한노인병학회 2000 Annals of geriatric medicine and research Vol.4 No.3

진동억제용 다중동흡진기의 효과에 관한 연구

안찬우,김동영,홍도관 동아대학교 환경문제연구소 1998 硏究報告 Vol.21 No.2

In a number of cases it appears expedient to install several absorbers of smaller masses instead of one. This may be due to the need to distribute the absorber's response along the construction, restrictions on the absorber's installation and transportation and other reasons. The application of multimass absorbers is not limited to protection from harmonic actions. The complete optimization of the absorber's parameters reduces to resonance amplitude. So, we studied characteristic of main vibration system and multi dynamic absorber's system for the optimal natural frequency ratio and damping ratio of multi dynamic absorber. Also we obtain the optimization of the multi dynamic vibration absorber's parameters using computer simulation for the damped main vibration system. In designing multi dynamic vibration absorber, we are presented for the optimum values of the mass, spring constant and damping coefficient of multi dynamic vibration absorbers.

百濟 漢文學의 水準에 對하여 : 文獻文을 中心으로

安東柱 호남대학교 1991 호남대학교 학술논문집 Vol.12 No.1

The purpose of this study is as follows: 1. Though many materials of Chinese classical literature in Paekje have disappeared. we can imagine from the cultural characteristics that there must have been lots of materials on Chinese classical literature in Paekje. 2. The formative period of Chinese classical literature in Paekje ranged from the moving of Chinese tribe to diplomatic intercourse between China and Paekje. and it was generalized during the Kin, Gunchogowang's reign. 3. About 10 pieces off Chinese literature in Paekje can be found and which show some characteristics of literary style. 4. Finally, the style of Chinese classical in Paekje was Pyun-San mixed one but mainly an antitheses.

함구리 황산폐액으로부터 LIX84-Kerosene-Span80-H₂SO₄계 유화형 액막법에 의한 구리의 분리 농축

안종관,안재우,신선명,김동진 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.4

The separation and extraction of copper from waste water solutions by the liquid surfactant membrane process using LM84 as an extractant and Span 80 as a surfactant were investigated . In extraction, the extraction rate of copper was greatly accelerated by the presence of sodium acetate and with the increase of pH in the aqueous feed solution. The optimum concentrations of LIX84 and Span 80 in the membrane phase were 7-10 vol. % and 2.5-3vol. %, respectively. Experiments also showed that the concentration ratio of copper was greatly enhanced with the decrease of the ratio of V_(e) and V_(w) and with the decreasing of A/O ratio. After the extraction process, the concentration of copper in the raffinate solution reduced to 1-2 ppm, and the concentration of copper in the internal aqueous solution increased to 20 gll. (Received February 11, 2004)