http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
A Rare Case of Hepatic T-Cell Rich B-Cell Lymphoma (TCRBCL) in a Juvenile Dog
CHUNG, Tae-Ho,LAMM, Catherine,CHOI, Young-Chul,LEE, Jung-Woo,YU, Dohyeon,CHOI, Ul-Soo The Japanese Society of Veterinary Science 2014 The Journal of veterinary medical science Vol.76 No.10
<P><B>ABSTRACT</B></P><P>A 7-month-old castrated male French Bull dog was presented with vomiting, lethargy, anorexia and weight loss of 2 weeks duration. The patient’s history and clinical manifestations of suspected hepatopathy were subjected to ultrasonography, radiography, biochemical investigations and cytology of hepatic lesion. The cytologic impression was hepatic lymphoma, which was later confirmed by histopathology. The neoplastic cells were strongly diffusely immunoreactive for PAX5, but not immunoreactive for CD3, and B lymphocyte specific clonal proliferation was detected using by assay of antigen receptor rearrangement. Large numbers of immunoreactive mature non-neoplastic lymphocytes were admixed with the neoplastic cell population. Therefore, the immunohistochemical results were definitively consistent with a T-cell rich B-cell lymphoma (TCRBCL). This is the first description of a hepatic TCRBCL in a juvenile dog showing a poor response to aggressive chemotherapy.</P>
( Dohyeon Lee ),( Kyoung Soon Choi ),( Daun Kim ),( Sunho Park ),( Woochan Kim ),( Kyoung-je Jang ),( Ki-taek Lim ),( Jong Hoon Chung ),( Hoon Seonwoo ),( Jangho Kim ) 한국농업기계학회 2017 바이오시스템공학 Vol.42 No.4
Purpose: Biocompatible capsules have recently been highlighted as a novel platform for delivering various components, such as drug, food, and agriculture pesticides, to overcome the current limitations of living systems, such as those in agriculture, biology, the environment, and foods. However, few active targeting systems using biocompatible capsules and physical forces simultaneously have been developed in the agricultural engineering field. Methods: Here, we developed an active targeting delivery platform that uses biocompatible alginate capsules and controls movements by magnetic forces for agricultural and biological engineering applications. We designed and fabricated large-scale biocompatible capsules, using custom-made nozzles ejecting alginate solutions for encapsulation. Results: To develop the active target delivery platforms, we incorporated iron oxide nanoparticles in the large-scale alginate capsules. The sizes of alginate capsules were controlled by regulating the working conditions, such as concentrations of alginate solutions and iron oxide nanoparticles. Conclusions: We confirmed that the iron oxide particle-incorporated large-scale alginate capsules moved actively in response to magnetic fields, which will be a good strategy for active targeted delivery platforms for agriculture and biological engineering applications, such as for the controlled delivery of agriculture pesticides and biocontrol agents.
Yoon, Dohyeon,Chung, Kyung Yoon,Chang, Wonyoung,Kim, Seung Min,Lee, Mi Jin,Lee, Zonghoon,Kim, Jaehoon American Chemical Society 2015 Chemistry of materials Vol.27 No.1
<P>Hydrogen-enriched reduced graphene oxide (RGO) was achieved using double-oxidized graphene oxide (GO2) as an anode in high-performance lithium batteries is reported. GO2 exhibited a much lower carbon-to-oxygen ratio, lower crystallinity, higher Brunauer–Emmett–Teller surface area, higher pore volume, and higher porosity as compared to graphene oxides produced using the typical modified Hummer’s method (GO1). The two forms of GO were reduced using two different reduction methods: supercritical isopropanol (scIPA) and heat treatment. The four types of RGOs synthesized using GO1/GO2 and scIPA/heat treatment exhibited significantly different chemical, morphological, and textural properties. The galvanostatic charge–discharge properties were highly dependent on the physicochemical properties of the RGOs. The scIPA-reduced GO2 exhibited superior electrochemical performance as compared to the thermally reduced GO1/GO2 and scIPA-reduced GO1. Highly reversible capacity (1331 mAh g<SUP>–1</SUP> at 50 mA g<SUP>–1</SUP> after 100 cycles), excellent rate-performance (328 mAh g<SUP>–1</SUP> at 5 A g<SUP>–1</SUP>), and good cycling stability up to 1000 cycles even at a current density of 10 A g<SUP>–1</SUP> were observed with the scIPA-reduced GO2 electrode. The characterization results suggested that a large amount of hydrogen-terminated groups, numerous defect sites, and large interlayer spacing have beneficial effects on the electrochemical performance of scIPA-reduced GO2.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/cmatex/2015/cmatex.2015.27.issue-1/cm503861r/production/images/medium/cm-2014-03861r_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cm503861r'>ACS Electronic Supporting Info</A></P>
Lee, Dohyeon,Choi, Kyoung Soon,Kim, Daun,Park, Sunho,Kim, Woochan,Jang, Kyoung-Je,Lim, Ki-Taek,Chung, Jong Hoon,Seonwoo, Hoon,Kim, Jangho Korean Society for Agricultural Machinery 2017 바이오시스템공학 Vol.42 No.4
Purpose: Biocompatible capsules have recently been highlighted as a novel platform for delivering various components, such as drug, food, and agriculture pesticides, to overcome the current limitations of living systems, such as those in agriculture, biology, the environment, and foods. However, few active targeting systems using biocompatible capsules and physical forces simultaneously have been developed in the agricultural engineering field. Methods: Here, we developed an active targeting delivery platform that uses biocompatible alginate capsules and controls movements by magnetic forces for agricultural and biological engineering applications. We designed and fabricated large-scale biocompatible capsules, using custom-made nozzles ejecting alginate solutions for encapsulation. Results: To develop the active target delivery platforms, we incorporated iron oxide nanoparticles in the large-scale alginate capsules. The sizes of alginate capsules were controlled by regulating the working conditions, such as concentrations of alginate solutions and iron oxide nanoparticles. Conclusions: We confirmed that the iron oxide particle-incorporated large-scale alginate capsules moved actively in response to magnetic fields, which will be a good strategy for active targeted delivery platforms for agriculture and biological engineering applications, such as for the controlled delivery of agriculture pesticides and biocontrol agents.
Yoon, Dohyeon,Hwang, Jieun,Kim, Dong Hyun,Chang, Wonyoung,Chung, Kyung Yoon,Kim, Jaehoon Elsevier science 2017 The Journal of supercritical fluids Vol.125 No.-
<P><B>Abstract</B></P> <P>TiO<SUB>2</SUB>-reduced graphene oxide (RGO) hybrids were prepared using one-pot, simultaneous reduction of graphene oxide (GO) to RGO and anchoring of TiO<SUB>2</SUB> nanoparticles on the surface of RGO in supercritical isopropanol. Numerous anchor sites facilitating heterogeneous nucleation of TiO<SUB>2</SUB> particles on GO, and extremely fast nucleation due to the supercritical alcohol led ultrafine, well-dispersed anatase TiO<SUB>2</SUB> nanoparticles to anchor to the RGO sheets in a single step. The unique synthetic approach developed herein was very effective for preventing restacking of graphene sheets during reduction, and for tightly anchoring TiO<SUB>2</SUB> nanoparticles to the RGO surface. When the TiO<SUB>2</SUB>-RGO with a TiO<SUB>2</SUB> loading of 48wt% tested as an anode in lithium-ion battery, it exhibited excellent electrochemical performance with a high reversible capacity of 229mAhg<SUP>−1</SUP> at 50mAg<SUP>−1</SUP> after 50 cycles and a high-rate performance of 115mAhg<SUP>−1</SUP> at 1Ag<SUP>−1</SUP>, and 95% of the initial capacity was retained even after 1000 cycles (at rate of 1Ag<SUP>−1</SUP>).</P> <P><B>Highlights</B></P> <P> <UL> <LI> One-pot, tight anchoring of TiO<SUB>2</SUB> to graphene sheets using supercritical alcohol. </LI> <LI> Uniform decoration of TiO<SUB>2</SUB> on graphene, preventing restacking of graphene sheets. </LI> <LI> High reversible capacity of 229mAhg<SUP>−1</SUP> at 50mAg<SUP>−1</SUP> after 50 cycles. </LI> <LI> Excellent high-rate performance of 115mAhg<SUP>−1</SUP> at 1Ag<SUP>−1</SUP> was achieved. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Cheon, Bo-Wi,Yoo, Dohyeon,Park, Hyojun,Lee, Hyun Cheol,Shin, Wook-Geun,Choi, Hyun Joon,Hong, Bong Hwan,Chung, Heejun,Min, Chul Hee Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.6
The aim of this study was to optimize the target, moderator, and collimator (TMC) in a neutron beam generator for the accelerator-based BNCT (A-BNCT) system. The optimization employed the Monte Carlo Neutron and Photon (MCNP) simulation. The optimal geometry for the target was decided as the one with the highest neutron flux among nominates, which were called as angled, rib, and tube in this study. The moderator was optimized in terms of consisting material to produce appropriate neutron energy distribution for the treatment. The optimization of the collimator, which wrapped around the target, was carried out by deciding the material to effectively prevent the leakage radiations. As results, characteristic of the neutron beam from the optimized TMC was compared to the recommendation by the International Atomic Energy Agent (IAEA). The tube type target showed the highest neutron flux among nominates. The optimal material for the moderator and collimator were combination of Fluental (Al<sub>2</sub>0<sub>3</sub>+AlF<sub>3</sub>) with <sup>60</sup>Ni filter and lead, respectively. The optimized TMC satisfied the IAEA recommendations such as the minimum production rate of epithermal neutrons from thermal neutrons: that was 2.5 times higher. The results can be used as source terms for shielding designs of treatment rooms.