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        FDG-PET Identification of Infected Pulmonary Artery Conduit Following Tetralogy of Fallot (TOF) Repair

        Yuyang Zhang,Hadyn Williams,Darko Pucar 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.1

        Tetralogy of Fallot (TOF) is one of the most common forms of cyanotic congenital heart disease usually managed by serial surgical repairs. The repaired prosthetic valve or conduit is susceptible to life-threatening infection. FDG-PET is an effective alternative to evaluate the source of infection when other examinations are inconclusive. We report an unusual case of an infected pulmonary artery conduit after TOF repair although the echocardiogram was negative for vegetation, which was later confirmed by surgery and pathology. The case highlights the role of FDG-PETas a problem-solving tool for potential endocarditis and cardiac device infection cases after complex cardiac surgery.

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        Unusual Contiguous Soft Tissue Spread of Advanced Malignant Mesothelioma Detected by FDG PET/CT

        Yuyang Zhang,Jamie Edwards,Hadyn Williams,Zhonglin Hao,Samir Khleif,Darko Pucar 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.2

        Malignant pleural mesothelioma (MPM) is atumor of mesodermal origin that arises from the serosaof the pleura, peritoneum, pericardium or tunicavaginalis. MPM is well known to have a poor prognosiswith a median survival time of 12 months. Accurate diagnosis,staging and restaging of MPM are crucial with[18F] flurodeoxy-D-glucose positron emission tomography(FDG PET/CT) playing an increasingly importantrole. Here we report a case of MPM with unusual contiguoussoft tissue spread of the tumor along the dermaland fascial planes characterized by PET/CT. Given thatthe loco-regional tumor in the thorax was under controlon PET/CT, the death of the patient was most likelyassociated with physiologic or metabolic causes associatedwith an extra-thoracic tumor.

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        Ipsilateral Malignant Axillary Lymphadenopathy and Contralateral Reactive Lymph Nodes in a COVID-19 Vaccine Recipient With Breast Cancer

        Mehmet Emin Adin,Jennifer Wu,Edvin Isuf,Edison Tsui,Darko Pucar 한국유방암학회 2022 Journal of breast cancer Vol.25 No.2

        Vaccine-related axillary nodal enlargement is a common benign condition that many mRNA vaccine receivers experience. However, a false attribution of axillary swelling to vaccination may result in delay in cancer care and potential disease progression, particularly in breast cancer patients presenting with ipsilateral axillary lymphadenopathy. We report the case of a 41-year-old pre-menopausal female who presented with suspicious axillary nodal enlargement and a right breast lump (triple-negative invasive ductal carcinoma) after recent administration of the second dose of Moderna mRNA coronavirus disease 2019 (COVID-19) vaccine. On imaging, bilateral axillary lymph nodes were detected. The ipsilateral rightsided node was proven to be metastatic, whereas contralateral nodes were related to a recent mRNA COVID-19 vaccination. Right-sided lymph node had intense uptake (maximum standardized uptake value [SUVmax] = 5), while the contralateral reactive nodes were mildly avid (SUVmax = 2.6). On magnetic resonance imaging, the right-sided node revealed asymmetric cortical thickening and marked cortical enhancement as opposed to normalappearing left-sided nodes.

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