백서 창상의 피복방법에 따르는 Muofibroblast의 생성 및 소실되는 과정의 실험적인 비교관찰

김한중,최희윤,조철현,이인승 大韓成形外科學會 1985 Archives of Plastic Surgery Vol.12 No.1

The question of how skin coverage affects contracting wounds has long been a significant problem in the study of wound contraction. Myofibroblasts appear to be well established as the cellular cause of wound contraction. Myofibroblasts are found in many types of contracting wounds, including granulating wounds and hypertrophic burn scars. Myofibroblasts in contracting wounds have definitive life cycles, being present when contraction is active and then disappearing when contraction has ceased. In this study, we observated comparatively quantitative changes in the surface area by planimetry and changes of myofibroblasts by electron microscope through 8 weeks according to the types of skin coverage. The purpose of this study was to evaluate the myofibroblast population in skin coveraged wounds in a rat model, which allowed frequent biopsies as well as precise identificaion of the interface of the skin coverage and the wound bed. The results of our experiments are as follows: 1. Granulating wound Contracted rapidly and had long persistence of myofibroblasts. 2. Split-thickness skin graft Contrated less and myofibroblasts were more rapidly decreased and were disappeared at 5 weeks later. 3. Full-thickness skin graft Minimum contracti aondnmyofibroblasts were very rapidly decreased and were disappeared at 4 weeks later. 4. Local flap No contraction and could not find myofibroblast. Slowly increase in size at begining. 5. Contraction was influenced by number and lasting time of myofibroblast.

기업가치 평가와 신용한도

金喆中 홍익대학교 경영연구소 2004 경영연구 Vol.29 No.-

차량의 방송 수신 전파 환경 분석에 관한 연구

김의태,김성철,이중근,양승완,전인학 漢陽大學校 工學技術硏究所 2001 工學技術論文集 Vol.10 No.-

본 논문에서는 이동 중인 차량의 수신 성능에 영향을 주는 전파 환경 측정을 위한 측정 셋업을 구성하고, 측정 결과 분석을 통한 수신 이상 현상의 원인을 밝혔다. 이를 위해 필요한 측정 파라메터의 정량적 설정과 측정 및 분석 방법을 제시하였다. In this paper we constitute the measurement setup of electromagnetic environment which has an effect on the radio receiver of vehicles an analyzed causes. This paper proposes various measurement and analysis methods for uncovering noise mechanism of vehicle receiver system.

自己資本費用의 再認識과 經濟的 附加價値

金喆中 홍익대학교 경영연구소 1993 경영연구 Vol.17 No.-

국내 주요 호수의 육수학적 조사(4): 주암호

김범철,박주현,허우명,임병진,황길순,최광순,최종수 江原大學校 附設 環境硏究所 2001 環境硏究 Vol.18 No.-

In this study limnological characteristics of Lake Juam was surveyed from June 1993 to May 1994 in order to provides important information regarding water resources. Seschi disc transparency, epilimnetic chlorophyll a(chl-a), tatal nitrogen(TN), total phosphorus(TP) concentration and primary productivity were in the range of 2.0~4.5 m, 0.9~13.6 mgChl/㎥, 0.78~2.32N/l, 11~56 mgP/㎥, 270~2,160mgCm^(-2)day^(-1), respectively. On the basis of TP, Chl-a and Secchi disc depth, the trophic state of Lake Juam can be classified as mesotrophic lake. The phosphorus inputs from non-point sources are concentrated in heavy rain episodes during the monsoon season. As a result, phosphorus concentration are higher in summer than in winter. TP loading from the watershed were estimated to be 0.9 gPm^(-2)yr(-1), which correspond to a boundary of the critical loading (1.0 gPm^(-2)yr(-1), which correspond to a boundary of the critical loading (1.0 gPm^(-2)yr(-1)) for eutrophication. From the results of the algal assay, both phosphous and nitrogen act as limiting nutrients in algal growth. The seasonal succession of phytoplankton community structure in Lake Juam was similar to that observed in other temperate lakes. Diatoms(Asterionella formosa and Aulacoseira granulata var. angustissima) were dominant in spring and winter, cyanobacteria (Microcystis aeruginosa, M. sp. and M. viridis) were dominant in warm season. The organic carbon, nitrogen and phosphorus content of lake sediment were 9.5~14.0 mgC/g, 1.01~1.82 mgN/g, and 0.51~0.65 mgP/g, respectively. The allochthonous organic carbon loading from the watershed and autochthonous organic carbon loading by primary production of phytoplankton were determined to be 1,122 tC/yr and 6,718 tC/yr, respectively. To prevent eutrophication of Lake Juam, nutrient management of watershed should be focus on reduction of fertilizer application, proper treatment of manure, and conservation of topsoil as well as point source.

신용위험 측정에 관한 연구

金喆中 홍익대학교 경영연구소 2003 경영연구 Vol.28 No.-

도립진자의 동역학과 제어알고리즘

김중완,최영철,김재헌 동아대학교 생산기술연구소 2001 生産技術硏究所硏究論文集 Vol.6 No.1

The results of this research is shown confirmly need and effect of closed loop control using ECP Model 505 Inverted Pendulum This is not construction as normal load-on cart Inverted Pendulum. This linkage mechanism includes a moment-arm counter-load to be able to adjust and control perpendicular and the horizon bars. It controled both horizontal bar and vertical bar for control inverted pendulum in gravity field. ECP Model 505 Inverted Pendulum system achieved PID, VSC for non-minimum phase and conditional stability plant (right-half plane poles and zeros) by adjusting Position of centered mass. Especially, the result of variable structure control was finely shown high performance of closed loop control that compensate unstable situations for multi-degree systems.

고지방식이가 백서 골격근 및 지방조직의 지방분해에 미치는 영향

김철희,정윤이,이성진,박중열,홍성관,김홍규,서교일,이기업 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.24 No.6

연구배경:지방산화의 증가가 골격근에서 인슐린 저항성을 유발한다는 주장이 꾸준히 제기되어 나왔으나, 최근 제2형 당뇨병 환자나 인슐린저항성 상태에서 골격근의 지방산화능이 저하되어 있다는 보고도 있어 논란이 있는 상태이다. 본 연구에서는 고지방식이를 투여하여 인슐린저항성을 유발한 백서에서 microdialysis 기법을 이용하여 조직내의 지방분해 결과로 간질액내로 방출되는 글리세롤 농도를 골격근 및 지방조직에서 직접 측정하여 지방분해의 변화를 알아보고자 하였다. 방법:정상 Sprague­Dawley 백서를 두 군으로 나누어 4주간 고지방식이 및 저지방식이를 투여하였다. 4주간 기저상태 및 고인슐린 정상혈당 클램프 중의 골격근 및 지방조직에 microdialysis probe를 삽입하고 일정한 농도의 글리세롤을 포함하는 dialysate를 통과시켜 주입액과 유출액의 글리세롤 농도 차이로부터 조직 간질의 글리세롤 농도를 산출하엿다. 결과:기저상태에서 골격근 및 지방조직 간질의 글리세롤 농도는 저지방식이군에 비하여 고지방식이군에서 유의하게 낮았다. 고인슐린 정상혈당 클램프 중에는 골격근 및 지방조직 간질의 글리세롤 농도가 양군에서 모두 억제되었는데, 기저 상태와 마찬가지로 골격근 및 지방조직 모두에서 저지방식이군보다 고지방식이 군에서 더 낮았다. 기저 상태에 대한 고인슐린 클램프중의 글리세롤 방출 억제 정도는 저지방식이군에 비하여 고지방식이군에서 덜 억제되는 경향을 보였는데, 골격근조직에서만 통계적으로 유의하였다. 결론:본 연구 결과는 고지방식이에 의한 인슐린저항성 모델에서 골격근 및 지방조직내 지방분해가 억제되어 있음을 보여주며, 기존의 포도당­지방산 cycle 이론과는 달리 조직내 지방산화의 증가보다는 지방산화능의 감소에 따른 세포내 지방축척이 인슐린저항성과 관련될 가능성을 시사하였다. Background : It has been hypothesized that increased fat oxidation reduces glucose utilization in skeletal muscle, and is responsible for the insulin resistance associated with obesity or high-fat feeding. In contrast, there have been reports that fat oxidation capacity was decreased in skeletal muscles from insulin resistant subjects. This study was undertaken to examine whether insulin resistance in high-fat fed rats is associated with increased lipolysis in skeletal muscle and adipose tissue. Methods : Two groups of Sprague-Dawley rats were fed either high-fat or low-fat diets for 4 weeks. Lipolysis in skeletal muscle and adipose tissue was determined by measurement of interstitial 1 glycerol concentrations by a microdialysis method in basal and hyperinsuline mic-euglycemic clamp conditions. Results : In basal state, plasma glycerol levels and interstitial glycerol concentrations of skeletal muscle, and adipose tissue were lower in high-fat fed than in low-fat fed rats. The degree of suppression of glycerol release by the hyperinsuline mia was smaller in the high-fat diet than in the low-fat diet group. However, plasma and interstitial glycerol concentrations during the hyperinsuline mic euglycemic clamps were also lower in the high-fat diet group. Conclusion : Lipolysis was decreased in skeletal muscle and adipose tissue of insulin resistant, high-fat fed rats. These results support the idea that limited fat oxidation capacity resulting in lipid accumulation in tissues, rather than increased fat oxidation perse, is responsible for the insulin resistance associated with high-fat feeding (J Kor Diabetes Asso 24:641~651, 2000).

불규칙파의 굴절에 관한 연구

김재중,김철현,김영의 동아대학교 건설기술연구소 1996 硏究報告 Vol.20 No.1

The concept of wave spectrum which represents the random characteristics of waves is introduced and analyzed in this study. Also time series analyses are done by using numerical model that computes the random wave transformation in the nearshore region. The characteristics of shoaling and refraction of random waves which is incident on the straight shorelines with parellel bottom contours are studied using the stecturm analysis. JONSWAP spectum in the deep water depth was converted into TMA specturn in the shallow water detph. TMA spectrum computes the spectrum of wind waves in finite water depth as a funtion of frectrum. This study way be helpful to determining the representative wave height and period for the random deseign waves of coastal structures in the shallow water.

내측두엽 간질에서 위스콘신카드 분류검사

김철호,이상암,유희정,강중구,이정교 대한간질학회 2003 대한간질학회지 Vol.7 No.1