DICOM-Based Multi-Center Electronic Medical Records Management System

Jui-Hung Kao,Chien-Yeh Hsu,Yu-Ping Sung,Wei-Pan Liao 보안공학연구지원센터 2010 International Journal of Bio-Science and Bio-Techn Vol.2 No.2

Predictor Packing in Developing Unprecedented Shaped Colloidal Particles

Mubarak Ali,I-Nan Lin,Chien-Jui Yeh 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.09

Developing anisotropic particles of different shapes has been a hot topic of research since decades as they possess special features not possible to achieve through other means. It is considered challenging to control atoms for developing their particles of certain size and shape. In this study, different shapes of gold particles were developed while employing a pulse-based electron–photon–solution interface process. Gold atoms, when they are in certain transition state, develop their monolayer assembly around the light glow known in argon plasma generating at the bottom of copper capillary known in cathode. The rate of uplifted gold atoms to develop monolayer assembly at solution surface is controlled by electron streams and traveling photons of high-density entering the solution. Gold atoms dissociated from the precursor on transforming photons (propagating through immersed graphite rod known in anode) to heat energy. Double-packets of nanoshape energy are generated under tuned pulse protocol when they are placed over the compact monolayer assembly resulting in tiny-sized particles of own shape. On the separation of joined tiny particles into two equilateral triangular-shaped tiny particles, each atom of their one-dimensional array elongated on both sides from the centre while exerting opposite poles forces of surface format. This results in convertion of each array of atoms into a structure of smooth elements. Due to immersing force of solution surface and their termination at the centre of light glow, tiny-shaped particles pack from different zones where their structures of smooth elements assemble to develop monolayers of developing particle in a certain shape. Developing particles of one-dimension undertake assembling of structures of smooth elements where packing of their tiny-shaped particles is from the near regions belonging to rearward sides of north–south poles at the solution surface, whereas, developing particles of multi-dimension undertake assembling of structures of smooth elements where packing of their tiny-shaped particles is from the regions of east–west poles and near regions of east–west poles on the solution surface. Depending on the number and orientation of assembled structures of smooth elements nucleating monolayers for different particles, their different anisotropic shapes develop. At fixed precursor concentration, increasing the process time results in developing particles of low aspect ratio. Under tuned parameters, particles of unprecedented features developed.

Tapping Opportunity of Tiny-Shaped Particles and Role of Precursor in Developing Shaped Particles

Mubarak Ali,I-N. Lin,Chien-Jui Yeh 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.7

Metallic colloids are frequently used in industry and provide understanding of science at microns to nanometers scales along with their applicability for various technologically important applications. Present investigations deal with morphology and structure of gold, silver and their binary composition while processing certain amounts of their solutions in a newly designed process and tapping opportunities of developing tiny-shaped particles. At tuned ratio of pulse OFF to ON time and when gold solution was processed, several tiny-shaped particles developed at the solution's surface. Such tiny particles exert force at the tip of each converting their structure of smooth element where steady-state immersing behavior directed them toward a common centre resulting into bind them for developing different geometric anisotropic shaped particles. Under identical parameters along with pulse time, processing solutions of silver nitrate and binary composition of chloroauric acid-silver nitrate result in the development of tiny particles having no specific shape where their assembling is under the mixed behavior of forces resulting in distorted particles. Elongation and deformation of gold and silver atoms while developing different structures are because of the plastically driven behavior of their electrons. In three-dimensional structures where atoms do not undergo transition to elongate, they retain the structure as it is, which is known as hcp structure or two-dimensional structure. Different nature of precursors along with morphology and structure of particles are discussed in this paper opening abundant avenues for research.

Self-organized multi-layered graphene-boron-doped diamond hybrid nanowalls for high-performance electron emission devices

Sankaran, Kamatchi Jothiramalingam,Ficek, Mateusz,Kunuku, Srinivasu,Panda, Kalpataru,Yeh, Chien-Jui,Park, Jeong Young,Sawczak, Miroslaw,Michałowski, Paweł Piotr,Leou, Keh-Chyang,Bogdanowicz, Robert,Li The Royal Society of Chemistry 2018 Nanoscale Vol.10 No.3

<P>Carbon nanomaterials such as nanotubes, nanoflakes/nanowalls, and graphene have been used as electron sources due to their superior field electron emission (FEE) characteristics. However, these materials show poor stability and short lifetimes, which prevent their use in practical device applications. The aim of this study was to find an innovative nanomaterial possessing both high robustness and reliable FEE behavior. Herein, a hybrid structure of self-organized multi-layered graphene (MLG)-boron doped diamond (BDD) nanowall materials with superior FEE characteristics was successfully synthesized using a microwave plasma enhanced chemical vapor deposition process. Transmission electron microscopy reveals that the as-prepared carbon clusters have a uniform, dense, and sharp nanowall morphology with sp<SUP>3</SUP> diamond cores encased by an sp<SUP>2</SUP> MLG shell. Detailed nanoscale investigations conducted using peak force-controlled tunneling atomic force microscopy show that each of the core-shell structured carbon cluster fields emits electrons equally well. The MLG-BDD nanowall materials show a low turn-on field of 2.4 V μm<SUP>−1</SUP>, a high emission current density of 4.2 mA cm<SUP>−2</SUP> at an applied field of 4.0 V μm<SUP>−1</SUP>, a large field enhancement factor of 4500, and prominently high lifetime stability (lasting for 700 min), which demonstrate the superiority of these materials over other hybrid nanostructured materials. The potential of these MLG-BDD hybrid nanowall materials in practical device applications was further illustrated by the plasma illumination behavior of a microplasma device with these materials as the cathode, where a low threshold voltage of 330 V (low threshold field of 330 V mm<SUP>−1</SUP>) and long plasma stability of 358 min were demonstrated. The fabrication of these hybrid nanowalls is straight forward and thereby opens up a pathway for the advancement of next-generation cathode materials for high brightness electron emission and microplasma-based display devices.</P>

Tissue Quality Comparison Between Heparinized Wet Suction and Dry Suction in Endoscopic Ultrasound-Fine Needle Biopsy of Solid Pancreatic Masses: A Randomized Crossover Study

Lin Meng-Ying,Wu Cheng-Lin,Su Yung-Yeh,Huang Chien-Jui,Chang Wei-Lun,Sheu Bor-Shyang 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.2

Background/Aims: A high-quality sample allows for next-generation sequencing and the administration of more tailored precision medicine treatments. We aimed to evaluate whether heparinized wet suction can obtain higher quality samples than the standard dry-suction method during endoscopic ultrasound (EUS)-guided biopsy of pancreatic masses. Methods: A prospective randomized crossover study was conducted. Patients with a solid pancreatic mass were randomly allocated to receive either heparinized wet suction first or dry suction first. For each method, two needle passes were made, followed by a switch to the other method for a total of four needle punctures. The primary outcome was the aggregated white tissue length. Histological blood contamination, diagnostic performance and adverse events were analyzed as secondary outcomes. In addition, the correlation between white tissue length and the extracted DNA amount was analyzed. Results: A total of 50 patients were enrolled, and 200 specimens were acquired (100 with heparinized wet suction and 100 with dry suction), with one minor bleeding event. The heparinized wet suction approach yielded specimens with longer aggregated white tissue length (11.07 mm vs 7.96 mm, p=0.001) and less blood contamination (p=0.008). A trend towards decreasing tissue quality was observed for the 2nd pass of the dry-suction method, leading to decreased diagnostic sensitivity and accuracy, although the accumulated diagnostic performance was comparable between the two suction methods. The amount of extracted DNA correlated positively to the white tissue length (p=0.001, Spearman̕s ρ=0.568). Conclusions: Heparinized wet suction for EUS tissue acquisition of solid pancreatic masses can yield longer, bloodless, DNA-rich tissue without increasing the incidence of adverse events (ClinicalTrials.gov. identifier NCT04707560).