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RISS 인기검색어
- 검색키워드
- 저자 : Cheng Xuesong (검색결과 4 건)
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Characteristics and prediction methods for tunnel deformations induced by excavations
Zheng, Gang,Du, Yiming,Cheng, Xuesong,Diao, Yu,Deng, Xu,Wang, Fanjun Techno-Press 2017 Geomechanics & engineering Vol.12 No.3
The unloading effect from excavations can cause the deformation of adjacent tunnels, which may seriously influence the operation and safety of those tunnels. However, systematic studies of the deformation characteristics of tunnels located along side excavations are limited, and simplified methods to predict the influence of excavations on tunnels are also rare. In this study, the simulation capability of a finite element method (FEM) considering the small-strain characteristics of soil was verified using a case study. Then, a large number of FEM simulations examining the influence of excavations on adjacent tunnels were conducted. Based on the simulation results, the deformation characteristics of tunnels at different positions and under four deformation modes of the retaining structure were analyzed. The results indicate that the deformation mode of the retaining structure has a significant influence on the deformation of certain tunnels. When the deformation magnitudes of the retaining structures are the same, the influence degree of the excavation on the tunnel increased in this order: from cantilever type to convex type to composite type to kick-in type. In practical projects, the deformation mode of the retaining structure should be optimized according to the tunnel position, and kick-in deformation should be avoided. Furthermore, two methods to predict the influence of excavations on adjacent tunnels are proposed. Design charts, in terms of normalized tunnel deformation contours, can be used to quantitatively estimate the tunnel deformation. The design table of the excavation influence zones can be applied to determine which influence zone the tunnel is located in.
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Kinetic modeling for chromatographic separation of cytosine monophosphate and uracil monophosphate
Haibin Qu,Yong Chen,Weixing Dai,Xuesong Liu,Yiyu Cheng 한국화학공학회 2006 Korean Journal of Chemical Engineering Vol.23 No.5
pharmaceutical industries. In this study, chromatographic separation of the two nucleotides CMP and UMP was sim-ulated by the equilibrium-dispersive (ED) model, and the adsorption isotherms in the ED model were determined bythe inverse method. Prediction performance of the model was validated under three diferent kinds of conditions andthe importance of selecting isotherms was discussed in detail. Excellent agreement was achieved with the experi-mental band profiles and the prediction of the ED model. The ED model with bi-Langmuir isotherm was especiallysuitable for simulating chromatographic separation of CMP and UMP. The error of prediction by the ED model with
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Numerical and experimental study of multi-bench retained excavations
Zheng, Gang,Nie, Dongqing,Diao, Yu,Liu, Jie,Cheng, Xuesong Techno-Press 2017 Geomechanics & engineering Vol.13 No.5
Earth berms are often left in place to support retaining walls or piles in order to eliminate horizontal struts in excavations of soft soil areas. However, if the excavation depth is relatively large, an earth berm-supported retaining system may not be applicable and could be replaced by a multi-bench retaining system. However, studies on multi-bench retaining systems are limited. The goal of this investigation is to study the deformation characteristics, internal forces and interaction mechanisms of the retaining structures in a multi-bench retaining system and the failure modes of this retaining system. Therefore, a series of model tests of a two-bench retaining system was designed and conducted, and corresponding finite difference simulations were developed to back-analyze the model tests and for further analysis. The tests and numerical results show that the distance between the two rows of retaining piles (bench width) and their embedded lengths can significantly influence the relative movement between the piles; this relative movement determines the horizontal stress distribution in the soil between the two rows of piles (i.e., the bench zone) and thus determines the bending moments in the retaining piles. As the bench width increases, the deformations and bending moments in the retaining piles decrease, while the excavation stability increases. If the second retaining piles are longer than a certain length, they will experience a larger bending moment than the first retaining piles and become the primary retaining structure. In addition, for varying bench widths, the slip surface formation differs, and the failure modes of two-bench retained excavations can be divided into three types: integrated failure, interactive failure and disconnected failure.
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Combining Ultrasound-Mediated Intracellular Delivery with Microfluidics in Various Applications
Huang Guangyong,Lin Lin,Wu Shixiong,Dang Haojie,Cheng Xuesong,Liu Ying,You Hui 한국바이오칩학회 2024 BioChip Journal Vol.18 No.1
Ultrasound-mediated intracellular delivery is one of the popular technologies based on membrane rupture at present. To date, ultrasound directly acts on a large number of cells to achieve cargo delivery and has been widely used in drug deliv-ery, disease therapy and other fields. However, the existing macroscopic methods can no longer meet the requirements of accurate tracking and analysis and are prone to extensive cell damage and even death. With the rapid advancements in microfl uidic technologies, the combination of ultrasound and microfluidics (CUM) technology can effectively improve the delivery efficiency and cell survival rates. This new technology has rapidly become a new direction and focus of research. Thus, we analysed the mechanism of sonoporation and the effect of acoustic waves in a microfluidic channel. In addition, we reviewed the application of these new technologies in terms of structure and fabrication of ultrasound transducers and microfl uidic devices. As regards our main objective, we hope to help researchers better understand the future developments and the challenges of new technologies. With this review, researchers can promote the development of new technologies to solve the current challenges of intracellular delivery and advance clinical applications.
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