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RISS 인기검색어
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- 저자 : Chang-Yong Cha (검색결과 626 건)
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서백종,장기육,박용근,채현석,한석원,이창돈,정인식,차상복,박두호 대한내과학회 1997 대한내과학회지 Vol.53 No.3S
저자들은 만성췌장염환자에서 지속적인 오심과 구토를 주소로 내원하여 십이지장협착으로 진단된 1예를 경험하였기에 보고하는 바이다. Duodenal stenosis resulting from fibroinflammatory process is a rare complication of chronic pancreatitis. The mechanism of duodenal stenosis seems to be related to ischemia and edema caused by persistent inflammation, which results in irreversible change of duodenal wall structure. We experienced a chronic alcoholic male patient with duodenal stenosis who had a history of choledochojejunostomy to relieve distal bile duct stenosis several years ago. He had suffered persistent postprandial nausea and vomiting for several months. Barium study of upper gastrointestinal tract and repeated endoscopy show narrowing lumen of duodenum with coarse nodular surface due to reactive inflammatory change.
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종 분포 모형을 활용한 새로운 구상나무 서식지 탐색, 그리고 식물보전 활용
김남신 ( Nam Shin Kim ),한동욱 ( Dong Uk Han ),차진열 ( Jin Yeol Cha ),박용수 ( Yong Su Park ),조현제 ( Hyeun Je Cho ),권혜진 ( Hye Jin Kwon ),조용찬 ( Yong Chan Cho ),오승환 ( Seung Hwan Oh ),이창석 ( Chang Seok Lee ) 한국환경복원기술학회(구 한국환경복원녹화기술학회) 2015 한국환경복원기술학회지 Vol.18 No.6
Korean fir(Abies koreana E.H.Wilson 1920), endemic tree species of Korean peninsula, is considered as vulnerable and endangered species to recent rapid environmental changes such as land use and climate change. There are limited activities and efforts to find natural habitats of Korean fir for conservation of the species and habitats. In this study, by applying SDMs (Species Distribution Models) based on climate and topographic factors of Korean fir, we developed Korean fir’s predicted distribution model and explored novel natural habitats. In Mt. Shinbulsan, Youngnam region and Mt. Songnisan, we could find korean fir’s two novel habitat and the former was the warmest(13°C in annual mean temperature), the driest(1,200mm∼1,600mm in annual rainfall) and relatively low altitude environment among Korean fir’s habitats in Korea. The result of SDMs did not include mountain areas of Gangwon-do as habitats of A. nephrolepis, because there were different contributions of key habitat environment factors, summer rainfall, winter mean temperature and winter rainfall, between A. koreana and A. nephrolepis. Our results raise modification of other distribution models on Korean fir. Novel habitat of Korean fir in Mt. Shinbulsan revealed similar habitat affinity of the species, ridgy and rocky site, with other habitats in Korea. Our results also suggest potential areas for creation of Korea fir’s alternative habitats through species reintroduction in landscape and ecosystem level.
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Menadione에 의해 유발된 간독성에 미치는 홍삼사포닌의 영향
장봉준,배춘식,조용성,차용호,박창원,조대현,장경진,Jang, Bong-jun,Bae, Chun-sik,Cho, Yong-seong,Cha, Yong-ho,Park, Chang-won,Cho, Tae-hyun,Chang, Kyung-jin 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.3
It is known that 2-methyl-1,4-naphtoquinone(menadione, MD) induces hepatotoxicities both in vivo and in vitro. These toxic effects are believed to result from oxidative damages to hepatocytes by "active oxygen" species via one-electron reduction of the naphtoquinone. The ginsenoside(GS) is a complex mixture of individual ginsenosides which is known to produce a range of effects on the cardiovascular and central nervous systems. In particular, GS has an antioxidant effect. In this experiment we studied the effect of GS from red panax ginseng(red ginseng total saponin, RGTS) on free radical-induced liver injuries by MD. Administration of MD($150{\mu}M$) caused an increase in aspartate aminotransferase(AST) activities and lipid peroxidation, decrease in alkaline phosphatase(ALP) activities and total bilirubin levels in blood, caused depletion of GSH and changes of antioxidant enzyme(superoxide dismutase, catalase) activities are shown in liver tissue. Administration of RGTS restored the AST levels that increased by MD, but catalase showed no significant changes. RGTS also had an effect of restoring the GSH level and had some synergistic effects with SOD. These data suggest that RGTS may have some protective effects on liver injury which is related with the oxygen free radical.
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세포내세균의 생태에 관한 연구(Ⅰ) : 포도구균과 거식세포
차창용,박원철,이승달,이승훈 최신의학사 1970 最新醫學 Vol.13 No.3
Numerous studies on the interactions between phagocytes and microorganisms were reported; however, there remain many aspects to be investigated. The phagocytosis and the fate of microorganisms may be influenced by the various factors such as the metabolism of the phagocytic cells, the nature of the bacterial surface substances, the physico-chemical factors of the environments, etc. It is well known that the staphylococcal infections are essentially intracellular infections and that the pathogenicities of Staph aureus and Staph. albus are quite different. It is also known that the metabolic activities of various cells may be influenced by the change of environmental temperature. A Thus, an experiment was planned and performed to study the mode of interactions betweqh rabbit macrophages and Staph. aureus or Staph. albus at different temperatures. The growth patterns of Staph. aureus and Staph. albus in the cell maintenance fluid (CMF) medium were followed for 5 hours at 37°C. and 33°C. Normal rabbit macrophages were collected from the peritoneal cavity, suspended in the the CMF medium and mixed with the suspension of staphylococci. The macrophage-bacteria suspensions were maintained for 5 hours at 37°C. and 330C., and the rate of the appearance of the macrophages containing the organisms, and the extracellular and intracellular viable populations of the organisms were studied. The results of the observation were summerazied as follow: 1) Staph. aureus began to increase, at 37°C. and 33C., more rapidly and actively than Staph. albus in the CMF medium. 2) The macrophages containing Staph. albus appeared more rapidly than the macrophages containing Staph. aureus. 3) The intra-and extra-cellular viable units of Staph. aureus showed more or less increase, and the percentage of the intracelluar units to the total viable units increased upto 3 hours and decreased thereafter. 4) The intra-and extra-cellular viable units of Staph. albus also increased, but the increase of the intracellular units was more sluggish than the extracellular units. The percentage of the intracellular units to the total units decreased after I hour. No significant difference was noticed between the interactions of the macrophage-bacteria at 37°C. and at 33°C.
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차창용 中央醫學社 1975 中央醫學 Vol.28 No.6
It has been well-known that the etiological agents for bacteremia have been changed since the advent of antimicrobial drugs, but in Korea there were a few reports based on the bacteremia or the bacterial species from the blood cultures .in recent years. Clinical-bacteriological analysis was done on 516 cases with the positive blood cultures in patients at the Seoul National University Hospital during the period of 1970 to 1974. The results were summarized as follows; 1) The bacterial strains from the blood cultures consisted of 205 strains of Gram(+) bacteria and 311 strains of Gram(-) bacteria, and Gram(+) bacteria have increased in frequency whereas Gram(-) bacteria have decreases. Among the bacterial species isolated, Salmonella group D were the most frequent and next -to this, coagulase(+) staphylococcus, coagulase(-) staphlylococcus, Alcaligenes fecalis, Escherichia coli, Pseudomonas aeruginosa, coliform (intermediate) bacilli, -a-hemolytic streptococcus, Enterobacter aerogenes etc., were in descending order 4 frequency of isolation. 2) Salmonella group D amounted to 140 cases with a tendency to be annually .decreasing in frequency, and were most frequently isolated from the patients with the age group of 21-40 years, in the male and on the medical ward. Antibiotic sensitivity of Salmonella group D has annually decreased and high susceptibility -was observed to chloramphenicol, neomycin and gentamycin. 3) Coagulase(+) staphylococci (102 cases) were most frequently isolated frompatients with the age group under 30 years, in the male and on the medical andpediatric ward, and were highly susceptible to lincomycin,leucomycin,neomycin and cloxacilIin with a tendency to be decreasing in susceptibility to vas-ions antibiotics. 4) Coagulase(-), staphylococci (56 cases) were most frequently isolated from the patients with the age group under 10 years in both sexes pediatric and medical ward, and were highly susceptible lincomycin,leucomycin,neomycin, and cloxacillin. 5) Alcaligenes fecalis (51 cases) were most freqently isolated from the patients with the age group under 10 years, in the female and on the medical and pediatric ward, and were moderately susceptible to gentamycin only. 6) Escherichia coIi (38 cases) were mostly frequently isolated from the patients with the age group of 21-40 years, in the female and on the medical ward, and were moderately susceptible to chloramphenicol, neomycin, colimycin, gentamycin and kenamycin. 7) Pseudomonas aeruginosa (24 cases) were isolated evenly from the patients of any age group, in the male and on the surgical ward, and were moderately susceptible to colimycin and gentamycin. 8) Coliforim (intermediate) bacilli (22 cases) were most frequently from the patients with the age group of 11-20 years, in both sexes and on the medical ward, and were moderately susceptible to gentamycin and neomycin. 9) a-hemolytic streptococci (19 cases) were most frequently isolated from the patients with the age group under 10 years, in the male and the pediatric ward, and were highly susciptable to lycomycin and gentamycin. 10) Enterobacter aerogenes (18 cases) were most frequently isolated from the patients with the age group under 10 years, in the female and on the medical and pediatric ward, and were moderately susceptible to colimycin and gentamycin.
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