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      • Effective length of counterpoise wire under lightning current

        He, Jinliang,Gao, Yanqing,Zeng, Rong,Zou, Jun,Liang, Xidong,Zhang, Bo,Lee, Jaebok,Chang, S. IEEE 2005 IEEE transactions on power delivery Vol.20 No.2

        In a high soil resistivity area, counterpoise wires are applied to decrease the grounding resistance of tower grounding devices. If the conductor of counterpoise wire is very long, although the power frequency grounding resistance of the tower grounding device is decreased, the lightning protection performance of the transmission line is still not good. The influences of the length of grounding electrodes on the lightning transient characteristic were analyzed. The dynamic and nonlinear effect of soil ionization around the grounding electrode was considered in the analysis model of transient characteristics for the grounding electrodes under lightning impulse. The counterpoise wire has an effective length when lightning passes through it. When the length of a grounding electrode exceeds the effective length, the grounding conductor will not be utilized effectively. The simulating experiments were performed to analyze influences of the length of the counterpoise wire on the impulse characteristics. The formulae to calculate the impulse effective lengths of counterpoise wires were proposed. The model proposed in the paper has been validated by comparing the numerical results with experimental tests.

      • Prognostic Model Built on Blood-based Biomarkers in Patients with Metastatic Colorectal Cancer

        He, Wen-Zhuo,Jiang, Chang,Yin, Chen-Xi,Guo, Gui-Fang,Rong, Ru-Ming,Qiu, Hui-Juan,Chen, Xu-Xian,Zhang, Bei,Xia, Liang-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

        Background: We had previously showed that the neutrophil lymphocyte ratio (NLR), ${\gamma}$-glutamyl transpeptidase (GGT) and carcinoembryonic antigen (CEA) are prognostic factors for metastatic colorectal cancer (mCRC) patients. In this study we developed a prognostic model based on these three indices. Materials and Methods: A total of 243 patients who were initially diagnosed as mCRC between 2005 and 2010 in the Sun Yat-sen University Cancer Center were studied. The endpoint was overall survival (OS). Results: NLR>3, elevated GGT and elevated CEA were confirmed as independent risk factors which could predict poor prognosis. Patients could be divided into three groups according to the number of risk factors they had. Those with two or three were defined as the high risk group, individuals with one risk factor as the modest risk group and patients without risk factor as the low risk group. The OS values for these three groups were 16.2 months (2.80~68.8), 24.2 months (4.07~79.0), and 37.2 months (12.6~87.8), respectively (p<0.001). Conclusions: We developed a simple but useful model based on NLR, GGT and CEA to provide prognostic information to clinical practice in highly selected mCRC patients. Further prospective and multi-center studies are warranted to test our model.

      • Numeral analysis model for shielding failure of transmission line under lightning stroke

        He, Jinliang,Tu, Youping,Zeng, Rong,Lee, J.B.,Chang, S.H.,Guan, Zhicheng IEEE 2005 IEEE transactions on power delivery Vol.20 No.2

        The shielding failure is the occurrence of a lightning stroke that bypasses the overhead ground wires and terminates on the phase conductors. The correct design to improve the shielding effect of transmission line to lightning is one of the key problems of transmission line design. A numerical analysis model for shielding failure of transmission line based on electromagnetic field theory is proposed in this paper. The electrical field of the system including lightning leader, transmission line and ground is solved, the range of lightning current striking the phase conductor is obtained, and the shielding failure probability of transmission line is calculated. The lightning leader model and the critical breakdown electrical field intensity of long gap are discussed. The analyzed results by numerical analysis model are compared with those by the electrogeometric model.

      • Influence of overhead transmission line on grounding impedance measurement of substation

        Zeng, Rong,He, Jinliang,Lee, Jaebok,Chang, S.,Tu, Youping,Gao, Yanqing,Zou, Jun,Guan, Zhicheng IEEE 2005 IEEE transactions on power delivery Vol.20 No.2

        How to precisely measure the grounding impedance of large-scale substations is a fundamental guarantee for the safe operation of power systems. If the ground wires were connected to the grounding grid, these ground wires would shunt a part of the injected measuring current and allow the measured grounding impedance to be smaller than the actual impedance of the grounding system. Based on an actual 500-kV grounding system, this paper discusses how to analyze the influence of the overhead ground wire on the measured grounding impedance and how to obtain the real grounding impedance of the grounding system. A numerical analysis model considering the grounding system, the transmission lines, towers, and their grounding devices, based on the multilayer soil model analyzed from field test data of apparent soil resistivity, was constructed to analyze the influence of ground wires and tower grounding resistances on grounding impedance, and the general effects of different parameters, such as tower impedance, grounding impedance, and circuits of transmission lines, were analyzed. The real grounding impedance of the substation with connected overhead ground wires was validated, and some useful results have been obtained, based on the field-measured values and numerical analysis.

      • Efficacy of Taxane-Based Regimens in a First-line Setting for Recurrent and/or Metastatic Chinese Patients with Esophageal Cancer

        Jiang, Chang,Liao, Fang-Xin,Rong, Yu-Ming,Yang, Qiong,Yin, Chen-Xi,He, Wen-Zhuo,Cai, Xiu-Yu,Guo, Gui-Fang,Qiu, Hui-Juan,Chen, Xu-Xian,Zhang, Bei,Xia, Liang-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13

        Objective: To compare the efficacy of taxane-based regimens in the first line setting retrospectively in Chinese patients with recurrent and/or metastatic esophageal cancer. Methods: We analyzed 102 recurrent and/or metastatic esophageal cancer patients who received taxanes-based regimens in a first-line setting from January 2009 to December 2013. Sixteen (15.7%) patients were administered Nab-PTX based chemotherapy and 86 patients (84.3%) received paclitaxel (PTX) or docetaxel (DTX) based chemotherapy. Patients in the PTX/DTX group could be further divided into TP (71 patients) and TPF (15 patients) groups. Results: The objective response rate (ORR) of all patients was 20.6%, and the disease control rate (DCR) was 67.6%. The median overall survival (OS) was 10.5 months (95% CI 10.1-16.4) and the median progression-free survival (PFS) was 6.04 months (95% CI 5.09-7.91). The DCR was higher in the TPF group than the TP group (93.3% vs. 59.1%; p = 0.015 ). There were no significant differences in ORR, OS, and PFS among Nab-PTX, TPF and TP groups. Conclusions: The three regimens of Nab-PTX based, TP and TPF proved active in a first line setting of Chinese patients with recurrent and/or metastatic esophageal cancer, and should thus be regarded as alternative treatments.

      • Applicability and Methods of Lean Production in Railway Transportation Organization: A Case Study of Urumqi Railway Bureau in China

        Li, Hong-Chang,Rong, Chao-He,Song, De-Xi The Korean Society for Railway 2008 International Journal of Railway Vol.1 No.2

        The concept of lean production originated and was applied mainly to manufacture industries Even proven successful with such companies as Toyota, lean production has to be combined railway transportation production in order to bring its function into full play. The paper analyzes for applicability of lean production in railway transportation production organization, puts forward implementation methods such as transportation resource integration, station-zone organization, dispatch command optimization, railway performance evaluation index system, etc., and makes an exemplification study of lean production of Urumqi Railway Bureau in China, which testifies the applicability and efficiency of railway lean production.

      • Soluble Expression of Recombinant Human Smp30 for Detecting Serum Smp30 Antibody Levels in Hepatocellular Carcinoma Patients

        Zhang, Sheng-Chang,Huang, Peng,Zhao, Yong-Xiang,Liu, Shu-Yan,He, Shu-Jia,Xie, Xiao-Xun,Luo, Gou-Rong,Zhou, Su-Fang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4

        Senescence marker protein 30 (SMP30), a hepatocellular carcinoma (HCC) associated antigen, was earlier shown by our research group to be highly expressed in HCC paracancerous tissues, but have low levels in HCC tissues. In order to detect anti-SMP30 antibody in serum of HCC patients, we established pET30a-SMP30 and pColdIII-SMP30 expression systems in Escherichia coli. However, the expression product was mainly in the form of inclusion bodies. In this research, we used several combinations of chaperones, four molecular chaperone plasmids with pET30a-SMP30 and five molecular chaperone plasmids with pColdIII-SMP30 to increase the amount of soluble protein. Results showed that co-expression of HIS-SMP30 with pTf16, combined with the addition of osmosis-regulator, and a two-step expression resulted in the highest enhancement of solubility. A total of 175 cases of HCC serum were studied by ELISA to detect anti-SMP30 antibody with recombinant SMP30 protein. Some 22 were positive and x2 two-sided tests all showed P>0.05, although it remained unclear whether there was a relationship between positive cases and clinical diagnostic data.

      • KCI등재후보

        Neuron Discharge and c-Fos Expression in the Nucleus of the Solitary Tract Following Electroacupuncture at Acupoints of the Yangming Stomach Meridian of Foot

        Jun-Feng He,Jie Yan,Jiang-Shan Li,Jian-Hua Liu,Chao Wang,Xiao-Rong Chang,Ya-Ting Qu 사단법인약침학회 2013 Journal of Acupuncture & Meridian Studies Vol.6 No.2

        The nucleus of the solitary tract (nucleus tractus solitarii; NTS) is a primary center for both visceral afferents and somatic afferents. Previous experiments have demonstrated that the NTS is closely connected to the stomach and acupoints in the Yangming Stomach Meridian of Foot (ST Meridian). In this study, extracellular recording and immunochemistry methods were used to analyze the discharge of neurons and c-Fos protein expression in the NTS following acupuncture at different acupoints and a nonacupoint. A total of 104 discharging neurons were detected in the NTS of 52 rats, of which 86 provided complete data. After acupuncture at Sibai (ST 2), Zusanli (ST 36), Neiting (ST 44), Quanliao (SI 18), and the nonacupoint, the neuron response rate in the NTS was 65.12%, 51.16%, 46.51%, 34.88% and 31.40% respectively. For neuron response rate, there was a significant difference among Sibai (ST 2), Zusanli (ST 36), Neiting (ST 44), Quanliao (SI 18), and the nonacupoint (p < 0.01 or p < 0.05). In the other 48 rats, the number of c-Fos immunoreactive neurons in the NTS by electroacupuncture (EA) at Sibai (ST 2) group was significantly higher than that EA at other acupoints and the nonacupoint (p < 0.05 or p < 0.01). EA at both Zusanli (ST 36) and Neiting (ST 44) increased c-Fos immunoreactive neurons significantly over EA at Quanliao (SI 18) and the nonacupoint (p < 0.05 or p < 0.01), while there was no difference between EA at Quanliao (SI 18) and the nonacupoint group (p > 0.05). The experiments demonstrated that the afferent convergence in NTS are different by body surface points stimulus, which suggests that the NTS might be a primary center in the central nervous system receiving acupoints stimulus from the ST Meridian.

      • Applicability and Methods of Lean Production in Railway Transprotation Organization: A Case Study of Urumqi Railway Bureau in China

        Li Hong-Chang,Rong Chao-He,Song De-Xi 한국철도학회 2008 International Journal of Railway Vol.1 No.2

        The concept of lean production originated and was applied mainly to manufacture industries with tangible products. Even proven successful with such companies as Toyota, lean production has to be combined with the characteristics of railway transportation production in order to bring its function into full play. The paper analyzes theoretical foundations for applicability of lean production in railway transportation production organization, puts forward implementation methods such as transportation resource integration, station-zone organization, dispatch command optimization, railway performance evaluation index system, etc., and makes an exemplification study of lean production of Urumqi Railway Bureau in China, which testifies the applicability and efficiency of railway lean production.

      • SCISCIESCOPUS

        Impacts of shape and height of upstream roof on airflow and pollutant dispersion inside an urban street canyon.

        Huang, Yuan-Dong,He, Wen-Rong,Kim, Chang-Nyung Ecomed 2015 Environmental Science and Pollution Research Vol.22 No.3

        <P>A two-dimensional numerical model for simulating flow and pollutant dispersion in an urban street canyon is firstly developed using the FLUENT code and then validated against the wind tunnel results. After this, the flow field and pollutant dispersion inside an urban street canyon with aspect ratio W/H?=?1 are examined numerically considering five different shapes (vaulted, trapezoidal, slanted, upward wedged, and downward wedged roofs) as well as three different roof height to building height ratios (Z H /H?=?1/6, 1/3, and 1/2) for the upstream building roof. The results obtained reveal that the shape and height of an upstream roof have significant influences on flow pattern and pollutant distribution in an urban canyon. A large single clockwise vortex is generated in the canyon for the vaulted upstream roof at Z H /H?=?1/6, 1/3, and 1/2, the trapezoidal and downward wedged roofs at Z H /H?=?1/6 and 1/3, and the slanted and upward wedged roofs at Z H /H?=?1/6, while a main clockwise vortex and a secondary counterclockwise vortex are established for the trapezoidal and downward wedged roofs at Z H /H?=?1/2 and the slanted and upward wedged roofs at Z H /H?=?1/3 and 1/2. In the one-vortex flow regime, the clockwise vortex moves upward and grows in size with increasing upstream roof height for the vaulted, trapezoidal, and downward wedged roofs. In the two-vortex flow regime, the size and rotational velocity of both upper clockwise and lower counterclockwise vortices increase with the upstream roof height for the slanted and upward wedged roofs. At Z H /H?=?1/6, the pollution levels in the canyon are close among all the upstream roof shapes studied. At Z H /H?=?1/3, the pollution levels in the canyon for the upward wedged roof and slanted roof are much higher than those for the vaulted, trapezoidal, and downward wedged roofs. At Z H /H?=?1/2, the lowest pollution level appears in the canyon for the vaulted upstream roof, while the highest pollution level occurs in the canyon for the upward wedged roof.</P>

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