Long second toe: its nail and skin changes

( Geun-hwi Park ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Nail can be affected by trauma, infection, and systematic disorders. In particular, the toe nails are exposed to the repeated and cumulative minor traumas, which usually result in thickened, splitted, and discolorated nails. Considering these, it can be inferred that the long second toe can be related to various nail and skin changes by repeated minor traumas such as friction in shoes, but the study or report on this topic hasn’t been done yet. Objectives: The purpose of this study was to introduce various nail and skin changes on long second toe. Methods: We analyzed the kinds of nail/skin changes of 50 patients with long second toe, enrolled at Pusan National University Hospitals (Busan and Yangsan) from 2013 to 2018. Results: There was no significant difference in the incidence of left and right toe and toenail, and 7 (14%) patients presented bilateral distribution. The most common nail change on long second toe was melanonychia (23, 46%), followed by subungual hematoma (15, 30%), onycholysis (2, 4%), subungual hyperkeratosis (2, 4%), onychomadesis (1, 2%), and retronychia (1, 2%). The most common skin change was corn (9, 18%), followed by paronychia (2, 4%). Twenty (20/50, 40%) patients also had other toe or toenail changes. Among them, the most common site was big toe/nail (13, 62%), and the most common change was subungual hematoma (8, 42%). Conclusion: Through this study, the dermatologists can recognize and diagnose the nail and skin changes of long second toe.

Projections of summertime ozone concentration over East Asia under multiple IPCC SRES emission scenarios

Lee, Jae-Bum,Cha, Jun-Seok,Hong, Sung-Chul,Choi, Jin-Young,Myoung, Ji-Su,Park, Rokjin J.,Woo, Jung-Hun,Ho, Changhoi,Han, Jin-Seok,Song, Chang-Keun Elsevier 2015 Atmospheric environment Vol.106 No.-

<P><B>Abstract</B></P> <P>We have developed the Integrated Climate and Air Quality Modeling System (ICAMS) through the one-way nesting of global–regional models to examine the changes in the surface ozone concentrations over East Asia under future climate scenarios. Model simulations have been conducted for the present period of 1996–2005 to evaluate the performance of ICAMS. The simulated surface ozone concentrations reproduced the observed monthly mean concentrations at sites in East Asia with high R<SUP>2</SUP> values (0.4–0.9), indicating a successful simulation to capture both spatial and temporal variability. We then performed several model simulations with the six IPCC SRES scenarios (A2, A1B, A1FI, A1T, B1, and B2) for the next three periods, 2016–2025 (the 2020s), 2046–2055 (the 2050s), and 2091–2100 (the 2090s). The model results show that the projected changes of the annual daily mean maximum eight-hour (DM8H) surface ozone concentrations in summertime for East Asia are in the range of 2–8 ppb, −3 to 8 ppb, and −7 to 9 ppb for the 2020s, the 2050s, and the 2090s, respectively, and are primarily determined based on the emission changes of NO<SUB>x</SUB> and NMVOC. The maximum increases in the annual DM8H surface ozone and high-ozone events occur in the 2020s for all scenarios except for A2, implying that the air quality over East Asia is likely to get worse in the near future period (the 2020s) than in the far future periods (the 2050s and the 2090s). The changes in the future environment based on IPCC SRES scenarios would also influence the change in the occurrences of high-concentrations events more greatly than that of the annual DM8H surface ozone concentrations. Sensitivity simulations show that the emissions increase is the key factor in determining future regional surface ozone concentrations in the case of a developing country, China, whereas a developed country, Japan would be influenced more greatly by effects of the regional climate change than the increase in emissions.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Change in ozone level is determined by the combination of NO<SUB>x</SUB> and NMVOC emissions. </LI> <LI> Ozone level over East Asia would get worse in the near future (the 2020s) than far future. </LI> <LI> A high-concentration event generally increases and more frequently occurs in the future. </LI> <LI> Change in ozone air quality in a developing country depends more on emissions change. </LI> <LI> Change in ozone air quality in a developed country depends more on climate change. </LI> </UL> </P>

Effect of Total Hip Arthroplasty on Ipsilateral Lower Limb Alignment and Knee Joint Space Width: Minimum 5-Year Follow-up

Choi Yun Seong,Park Jung-Wee,Kim Tae Woo,Kang Kee Soo,Lee Young-Kyun,Koo Kyung-Hoi,Chang Chong Bum 대한의학회 2023 Journal of Korean medical science Vol.38 No.20

Background: This study aimed to 1) assess the effect of total hip arthroplasty (THA) on coronal limb alignment, namely, the hip–knee–ankle angle (HKA), 2) identify factors that determine changes in the HKA, and 3) determine whether alignment changes influence the knee joint space width. Methods: We retrospectively evaluated 266 limbs of patients who underwent THA. Three types of prostheses with neck shaft angles (NSAs) of 132°, 135°, and 138° were used. Several radiographic parameters were measured in the preoperative and final radiographs (at least 5 years after THA). A paired t-test was used to confirm the effect of THA on HKA change. Multiple regression analysis was performed to identify radiographic parameters related to HKA changes following THA and changes in knee joint space width. Subgroup analyses were performed to reveal the effect of NSA change on the HKA change, and the proportion of total knee arthroplasty usage and changes in radiographic parameters between maintained joint space and narrowed joint space groups were compared. Results: The preoperative mean HKA was 1.4° varus and increased to 2.7° varus after THA. This change was related to changes in the NSA, lateral distal femoral angle, and femoral bowing angle. In particular, in the group with a decrease in NSA of > 5°, the preoperative mean HKA was largely changed from 1.4° varus to 4.6° varus after THA. The prostheses with NSA of 132° and 135° also led to greater varus HKA changes than those with an NSA of 138°. Narrowing of the medial knee joint space was related to changes in the varus direction of the HKA, decrease in NSA, increase in femoral offset. Conclusion: A large reduction in NSA can lead to considerable varus limb alignment after THA, which can have adverse effects on the medial compartment of the ipsilateral knee.

장기간 숙성에 따른 죽초 및 목초액의 이화학적 변화

구창섭,문성필,박상범,권수덕 한국목재공학회 2002 목재공학 Vol.30 No.4

졸참나무, 맹종죽 및 소나무로부터 제조한 미정제 죽초 및 목초액을 약 1년 간 저장하고, 이들의 이화학적 변화를 주기적으로 분석하였다. pH, 유기산·용해타르 함량 및 비중은 전 숙성기간 중 큰 변화가 관찰되지 않았다. 그러나 색차의 경우 7∼10개월 사이에서 현저한 변화를 나타내었다. 또한 이 기간동안에 이들 죽초 및 목초액의 색깔은 연한 노랑 띤 오렌지색에서 자주색과 오렌지색으로 크게 변화하였다. 죽초 및 목초액 중 유기산 및 중성 성분(dihydro-2(3H)-furanone, furfural, furfuryl alcohol, 2-hydroxy-1-methyl-1-cyclopenten-3-one, 1-hydroxy-2-propanone, methanol)들의 함량은 3개월 간격으로 주기적인 증감을 나타내었다. 특히 유기산류와 중성 성분들의 관계는 0.92 정도의 높은 상관관계를 나타내었다. 페놀류의 함량은 비록 유사한 주기적인 증감이 관찰되었으나, 그 함량의 경우 숙성 전 기간에 걸쳐 감소하였다. Three different kinds of the crude vinegars obtained from oak(Quercus serrata), bamboo(Phyllostachys pubescens) and pine(Pinus densiflora) species were stored for approximately one year and periodically analyzed to monitor their physicochemical changes. Small changes in physical properties, such as the pH, specific gravity and amount of organic acids as well as water-soluble tar were observed in the entire course of aging period. However, the color difference of the vinegars showed a remarkable change between 7 and 10 months. In addition, these vinegars' colors changed from light yellowish orange to much deeper purple and orange during this period. The amount of organic acids and neutral compounds(dihydro-2(3H)-furanone, furfural, furfuryl alcohol, 2-hydroxy-1-methyl-1-cyclopenten-3-one, 1-hydroxy-2-propanone and methanol) in the vinegars increased or decreased periodically every three months. A good linear relationship (correlation coefficient of ca. 0.92) was obtained between the amount of organic acids and the amount of neutral compounds in such changes. However, although the amount of phenols increased or decreased periodically, its amount was decreased over the entire aging period.

한ㆍ일 도시가스산업의 생산성 비교분석

최인수(In Su Choi),도범성(Bum Sung Do),박창수(Chang Soo Park),박중구(Jung Gu Park) 한국가스학회 2009 한국가스학회지 Vol.13 No.2

본고는 21세기 들어 고유가와 기후변화협약에 대응하여 중요성이 더해지고 있는 한국과 일본의 도시가스기업의 생산성을 분석하였다. 맘퀴스트 생산성 지수(Malmquist Productivity Index: MPI)를 통해 1997년부터 2005년까지 한국 30개, 일본 5개 기업들의 재무제표를 활용하여 기간 전체로, 그리고 수요의 구조변화를 나타내었던 2000년을 기준으로 이전과 이후의 생산성을 평가하였다. 분석의 결과, 첫째, 1996년~2005년 전체 기간의 MPI 누적지수에서 한국의 도시가스산업이 일본보다 상위에 있는 것으로 분석되었다. 그러나 기간별로 본 MPI 개선효과는 일본의 경우 1997~2000년 동안 -1.03%에서 2001~2005년 동안에는 -1.72%로 근소한 차이를 나타낸 반면, 한국의 경우에는 전반기 0.37%(금융외환위기를 경험한 98년 제외시 0.80%)이었지만 후반기에 -0.60%로 악화된 것으로 나타났다. 둘째, 후반기 한국의 MPI 악화는 기술적 효율성 지수보다는 기술변화 지수가 전반기 -0.88%(98년 제외시 0.29%)에서 후반기 -1.29%로 크게 악화된 것에 기인하는 것으로 분석되었다. 이에 따라 한국의 도시가스사업은 2001년 이후 악화되고 있는 생산성 증가율과 악화의 요인이 되고 있는 기술변화를 개선하는 정책적 노력이 필요하다. This article makes a comparative analysis on the productivity in gas distribution industry between Korea and Japan, using Malmquist productivity index(MPI). The estimated MPI during 1997~2005 shows that the productivity of Korean gas distribution industry has been generally higher than that of Japanese gas distribution industry. But Korean MPI made a drastic change from positive improvement (+ 0.37) during 1997~2000 to severe deterioration (-0.60) during 2001~2005, while Japan MPI has seldom changed. This change of Korean MPI is analyzed to result from the worsening of technical change rather than technical efficiency change. According to this result, Korean gas distribution industry needs to improve the technical change.

만성 신부전증 환자의 중증 고혈당에 따른 의식변화 결핍에 대한 연구

박은주,강성귀,한상웅,김호중,이창범,임천규,박성광,윤경택,위형중,안유헌 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.6

In diabetic patients who were being treated with hemodialysis, coma and other neurological deficits did not occur in spite of extremely elevated serum glucose levels. In this report, we compared diabetic patients with renal failure in severe hyperglycemia with nonketotic hyperosmolar coma patients with normal renal function to know what affect mental changes. Mental changes were not present in diabetic patients with renal failure. These patients with renal failure showed more severe hyperglycemia, but corrected serum sodium concentration and calculated effective serum osmolality were low. So it is suggested that corrected serum sodium concentration and effective serum osmolality are more important factor affecting mental changes than high blood glucose levels in diabetic patients with renal failure, due to absence of osmotic diuresis.

Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice

Yoon, Hye Eun,Kim, Eun Nim,Kim, Min Young,Lim, Ji Hee,Jang, In-Ae,Ban, Tae Hyun,Shin, Seok Joon,Park, Cheol Whee,Chang, Yoon Sik,Choi, Bum Soon Hindawi Publishing Corporation 2016 Oxidative medicine and cellular longevity Vol.2016 No.-

<P><I>Background</I>. This study evaluated whether the change in the renin-angiotensin system (RAS) is associated with arterial aging in mice.<I> Methods</I>. Histologic changes and expressions of transforming growth factor-<I>β</I> (TGF-<I>β</I>), collagen IV,<I> fibronectin</I>, angiotensin II (Ang II), angiotensin-converting enzyme (ACE), angiotensin-converting enzyme 2 (ACE2), angiotensin II type 1 receptor (AT1R), angiotensin II type 2 receptor (AT2R), prorenin receptor (PRR), Mas receptor (MasR), endothelial nitric oxide synthase (eNOS), NADPH oxidase 2 and oxidase 4 (Nox2 and Nox4), 8-hydroxy-2′-deoxyguanosine (8-OHdG),<I> 3-nitrotyrosine</I>, and superoxide dismutase 1 and dismutase 2 (SOD1 and SOD2) were measured in the thoracic aortas from 2-month-old, 12-month-old, and 24-month-old C57/BL6 mice.<I> Results</I>. Twenty-four-month-old mice showed significantly increased aortic media thickness and expressions of TGF-<I>β</I>, collagen IV, and fibronectin, compared to 2-month-old and 12-month-old mice. The expressions of PRR, ACE, and Ang II, and AT1R-positive area significantly increased, whereas expressions of ACE2 and MasR and AT2R-positive area decreased with age. The expressions of phosphorylated serine<SUP>1177</SUP>-eNOS, SOD1, and SOD2 decreased, and the 8-OHdG-positive area and the 3-nitrotyrosine-positive area increased with age. The expression of Nox2 significantly increased with age, but that of Nox4 did not change.<I> Conclusions</I>. The enhanced PRR-ACE-Ang II-AT1R axis and reduced ACE2-MasR axis were associated with arterial aging in mice. </P>

발달장애 청소년의 문제행동 감소를 위한 집단미술치료 사례

박창범(Park Chang Bum) 한국통합예술심신치유학회 2017 통합심신치유연구 Vol.4 No.2

본 연구는 장애인주간보호시설을 이용하는 발달장애 청소년에게 집단미술치료 프로그램을 실시하여 문제행동 개선에 어떠한 영향을 미치는지 알아보는 것이다. 사례집단은 2명의 여자와 2명의 남자로 특수학교와 일반학교에 재학중인 지적장애 2, 3급의 발달장애 청소년으로 주의력과 관계성, 공격성의 문제행동이 있는 총 4명으로 구성하였으며, 연령은 15세부터 21세까지이다. 프로그램은 2017년 1월부터 3월까지 매 주 2회기씩 50분으로 총 12회기를 진행하였으며, 선행연구를 통하여 초기 3회기, 중기 6회기, 후기 3회기로 구성하였다. 프로그램의 효과성 분석은 행동상의 문제를 연구자와 사회재활교사와의 상담을 통해서 선정된 주의력, 관계성, 공격성의 차이를 시설의 종사자들에게 행동관찰 기록지를 통해 사전과 사후를 검사하여 비교하였으며 회기별 변화를 기술하였다. 또한 양적 데이터로는 사례수는 적지만 사전, 사후 t검정을 통해 비교하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 주의력이 향상되었다. 둘째, 동료들 간 관계성이 향상되었다. 셋째, 동료를 때리거나 물건을 파손하는 등의 공격성이 감소되었다. 따라서 발달장애 청소년들에게 실시한 집단미술치료 프로그램은 문제행동의 개선에 긍정적인 영향을 미치는 것을 알 수 있었다. This study was to identify how group art therapy has effect on improving problem behavior of adolescents with developmental disabilities who used a daycare center for disabilities. The subjects for this case study were 2 females and 2 males, who were aged from 15 to 21 and attended to special-education school and general school. They were 2nd and 3rd class intellectual disabilities having problem behavior with attentiveness, relationship and aggression. With preceding research, a total of 12 sessions of the program consisted of 3 session of early stage, 6 sessions of mid stage and 3 sessions of latter stage and was carried out 2 sessions a week for 50 minutes. For the effectiveness analysis of the program, the staffs in the center had carried out pre and post test with the behavioral observation recording card and then the change rate that selected by consultation between researcher and social rehabilitation teacher were compared and described the sessional change. Furthermore, pre and post t-test was used although it was small cases as quantitative data. The main results are as follows. First, the attentiveness increased. Second, relationship with other people increased. Third, there was decrease in aggression which is hitting people or throwing stuffs. Therefore, it was showed that the group art therapy conducting with adolescents with developmental disabilities had a positive effect on improving problem behavior.

Differences in Resumption of Orthopedic Surgery According to Characteristics of Surgery during COVID-19 Pandemic: National Registry Data

Hyung Jun Park,Moon Jong Chang,Tae Woo Kim,Chong Bum Chang,Seung-Baik Kang 대한정형외과학회 2023 Clinics in Orthopedic Surgery Vol.15 No.2

Background: Healthcare services have been restricted after the coronavirus disease 2019 (COVID-19) outbreak. With the pandemic still ongoing, the patterns of orthopedic surgery might have changed. The purpose of this study was to determine whether the reduced volumes of orthopedic surgery were recovered over time. Among the trauma and elective surgery, which accounted for most orthopedic surgical procedures, we also sought to elucidate whether the changes in the volumes of orthopedic surgery differed according to the type of surgery. Methods: The volumes of orthopedic surgery were analyzed using the Health Insurance Review and Assessment Service of Korea databases. The surgical procedure codes were categorized depending on the characteristics of the procedures. The actual volumes of surgery were compared with the expected volumes to elucidate the effect of COVID-19 on surgical volumes. The expected volumes of surgery were estimated using Poisson regression models. Results: The reducing effect of COVID-19 on the volumes of orthopedic surgery weakened as COVID-19 continued. Although the total volumes of orthopedic surgery decreased by 8.5%–10.1% in the first wave, those recovered to a 2.2%–2.8% decrease from the expected volumes during the second and third waves. Among the trauma and elective surgery, open reduction and internal fixation and cruciate ligament reconstruction decreased as COVID-19 continued, while total knee arthroplasty recovered. However, the volumes of hemiarthroplasty of the hip did not decrease through the year. Conclusions: The number of orthopedic surgeries, which had decreased due to COVID-19, tended to recover over time, although the pandemic was still ongoing. However, the degree of resumption differed according to the characteristics of surgery. The findings of our study will be helpful to estimate the burden of orthopedic surgery in the era of persistent COVID-19.

만성 신부전증 환자의 중중 고혈당에 따른 의식 변화 결정에 대한 연구

위형중,이창범,박성광,강성귀,임천규,박은주,윤경택,한상웅,안유헌,김호중· 대한신장학회 2000 대한신장학회잡지 Vol.19 No.6