Catenary 곡면을 갖는 막구조물의 치환기법에 관한 연구

임채욱,송평훈,김승덕,송호산 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

Membrane structure systems and cable net structure systems are attracting people's attention as they are used in many buildings because of their light materials and airy appearances. If a membrane structure system or a cable net structure system does not have sufficiently high initial stiffness, it may be in unstable state. But if the initial stiffness is secured, the system will be in stable state. In this study the nonlinear finite element formulae for membrane and cable members considering geometric nonlinearity is derived, and then a catenary's membrane structure, and a tension membrane structure by Nass(Nonlinear Analysis for Spatial Structures) program is analyzed. The suitable scheme, which membrane structure are assigned by cable elements for overcoming the unfitted shape problem, is shown that the section of cable is assigned by element's area.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

‘Hwimori-gold’ Kimchi cabbage Yield and Sensorial Related Compounds Grown under Bifacial Agrophotovoltaic System

Seung-Hun Chae,Kang-Mo Ku 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.10

Renewable energy including wind power and solar power has been gain attention. To save land usage, agrophotovoltaics (APV) is suggested as one of the efficient renewable energy generating method. In order to evaluate Kimchi cabbage growth and quality under bifacial APV, ‘Hwimori-gold’ Kimchi cabbage seedlings (30-days old) were transplanted to both open-field and APV area. The growing period from transplanting to harvest was 90 d in the 2019 Fall (2019. 9. 6 ~12. 4) and 82 d in the 2020 Fall (2020. 9. 6~ 11. 27). Kimchi cabbage head average weight in 2019 and 2020 from open-field, bifacial_A (A solar panel company, located west side), and bifacial_B (B solar panel company, located center) were 4.4kg, 4.0kg, and 3.1kg, respectively. Kimchi cabbage head average weight loss (%) in 2019 and 2020 from bifacial_A and bifacial_B were 9% and 29%, respectively. Thus, overall Kimchi cabbage head weight loss was 19% across different area of bifacial solar panel over 2 years.Seven glucosinolates (GS) were detected 2019 and 2020 Fall (progoitrin, glucoraphanin, gluconapin, glocubrassicin, 4-methoxyglubrassicin, gluconasturtiin, and neoglucobrassicin) by high performance liquid chromatograph. Total GS concentration was not significantly different among treatments both 2019 and 2020 growing years. The major glucosinolate was 4-methoxyglucobrassicin in Kimchi cabbage (47.5%). 4-methoxyglucobrassicin of 2020 Kimchi cabbage grown from bifacial_B was significantly higher than those from open field. Eight GS hydrolysis products of Kimchi cabbage were detected 2019 and 2020 Fall (phenethyl isothiocyanate, 3-phenylpropionitrile, erucin nitrile, erucin, brassicanapin, 1-cyano-3, 4-epithiobutane epithionitrilegluconapin, 1-cyano-4, 5-epithiopentane, and 3-Butenyl isothiocyanate) by gas chromatograph-mass spectrometry. The major GS hydrolysis products were 1-cyano-3, 4-epithiobutane epithionitrilegluconapin (gluconapin, 25%) and 1-cyano-4, 5-epithiopentane (glucobrassicanapin, 42%) in 2019 Fall and 3-phenylpropionitrile (gluconasturtiin, 28%) and 1-cyano-4, 5-epithiopentane (glucobrassicanapin, 25%) in 2020 Fall. Total GS hydrolysis products and total sugar contents (glucose, fructose, and sucrose) were not significantly different among treatments. Our data suggests there was no significant difference in taste and flavor compounds by growing under APV.

Pre-hospital delay and emergency medical services in acute myocardial infarction

( Seung Hun Lee ),( Hyun Kuk Kim ),( Myung Ho Jeong ),( Joo Myung Lee ),( Hyeon-Cheol Gwon ),( Shung Chull Chae ),( In-Whan Seong ),( Jong-Seon Park ),( Jei Keon Chae ),( Seung-Ho Hur ),( Kwang Soo Ch 대한내과학회 2020 The Korean Journal of Internal Medicine Vol.35 No.1

Background/Aims: Minimising total ischemic time (TIT) is important for improving clinical outcomes in patients with ST-segment elevation myocardial infarction who have undergone percutaneous coronary intervention (PCI). TIT has not shown a significant improvement due to persistent pre-hospital delay. This study aimed to investigate the risk factors associated with pre-hospital delay. Methods: Individuals enrolled in the Korea Acute Myocardial Infarction Registry-National Institutes of Health between 2011 and 2015 were included in this study. The study population was analyzed according to the symptom-to-door time (STDT; within 60 or > 60 minutes), and according to the type of hospital visit (emergency medical services [EMS], non-PCI center, or PCI center). Results: A total of 4,874 patients were included in the analysis, of whom 28.4% arrived at the hospital within 60 minutes of symptom-onset. Old age (> 65 years), female gender, and renewed ischemia were independent predictors of delayed STDT. Utilising EMS was the only factor shown to reduce STDT within 60 minutes, even when cardiogenic shock was evident. The overall frequency of EMS utilisation was low (21.7%). Female gender was associated with not utilising EMS, whereas cardiogenic shock, previous myocardial infarction, familial history of ischemic heart disease, and off-hour visits were associated with utilising EMS. Conclusions: Factors associated with delayed STDT and not utilising EMS could be targets for preventive intervention to improve STDT and TIT.

Changes in Quality Characteristics of Pickled Purple Radish during Storage

Seung-Hun Chae,Sang-Hyun LEE,Seung-Hwan Kim,Jae-Hak Moon,Jeong-Yong Cho 한국원예학회 2023 한국원예학회 학술발표요지 Vol.2023 No.10

Metabolite Changes and Elastase Activity of Beach Rose (Rosa rugosa) Fruit and Seed from Various Ripening Stages

Seung Hun Chae,Kang Mo Ku,Tae HO Han,Young Sang Lee,Jin Hee Kim 한국원예학회 2020 한국원예학회 학술발표요지 Vol.2020 No.11

Kimchi cabbage (Brassica rapa subsp. pekinensis [Lour.]) Metabolic changes during growing seasons in the Republic of Korea

Chae Seung-Hun,Min Sung Gi,Moon Hyeon-Woo,Jung Young Bae,Park Sung Hee,Seo Hye-Young,구강모 한국원예학회 2024 Horticulture, Environment, and Biotechnology Vol.65 No.1

Kimchi cabbage is a cool-season plant, but it is grown year-round to meet the high demand for kimchi production. Understanding the plant’s seasonal characteristics is crucial for ensuring consistent quality. However, kimchi cabbages are grown in diverse locations with varied growing conditions and soil types, which creates an obstacle for producing uniform kimchi. To address this issue, we conducted research on sensorial-related metabolites and glucosinolates to char acterize kimchi cabbages from four seasons in the Republic of Korea. Our fi ndings revealed that fall and winter-grown kimchi cabbages had higher levels of compatible solutes (proline and sucrose) compared to those from spring and sum mer. These diff erences are likely due to low temperatures after the heading stage and freezing soil that induces drought stress. Additionally, extensive pest damage in the spring and summer increased the bitterness of kimchi cabbage, which may be attributed to neoglucobrassicin. These kimchi cabbage characteristics were confi rmed with fi ve cultivars grown in Naju, Jeollanam Province, for the spring and fall seasons. Our study suggests that kimchi cabbages grown in spring and summer have similar metabolite levels and increasing temperature regimes, a trend also found in fall/winter-grown kimchi cabbages. This study is the fi rst attempt to characterize kimchi cabbage attributes grown during four diff erent seasons.

Broccoli, a Promising Crop for Agrophotovoltaics: its Quality and Yield Changes under Solar Panel in Republic of Korea

Seung-Hun Chae,Kang-Mo Ku,Hye Joung Kim,Tae Ho Han 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.5

Intravesical bacillus Calmette–Guérin-induced myopathy presenting as rhabdomyolysis: a case report

Chae Hun Lee,Byeong Joo Choi,Jung Hun Kim,Tae Woong Yang,Gi Jeong Kim,Ha Young Shin,Se Hoon Kim,Seung Woo Kim 영남대학교 의과대학 2023 Yeungnam University Journal of Medicine Vol.40 No.4

Intravesical bacillus Calmette–Guérin (BCG) instillation is an adjuvant treatment for non–muscle-invasive urinary bladder cancer. Although most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have been reported. Only a few cases of BCG-related rhabdomyolysis have been reported. In this study, we present the case of a 72-year-old woman who developed severe weakness and hyperCKemia following intravesical BCG instillation. A muscle biopsy was performed, and a diagnosis of drug-induced myopathy was made.

Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults

Lee, Seung Hun,Kim, Ju Han,Jeong, Myung Ho,Park, Hyukjin,Jeong, Yun Ah,Ahn, Youngkeun,Kim, Jong Hyun,Chae, Shung Chull,Kim, Young Jo,Hur, Seung Ho,Seong, In Whan,Hong, Taek Jong,Choi, Donghoon,Cho, My The Korean Society of Cardiology 2015 Korean Circulation Journal Vol.45 No.4

<P><B>Background and Objectives</B></P><P>This study aims to investigate the clinical features, angiographic findings, and outcomes of younger Korean ST-segment elevation myocardial infarction (STEMI) patients.</P><P><B>Subjects and Methods</B></P><P>We analyzed major adverse cardiac events (MACE) in the Korea Acute Myocardial Infarction Registry from November 2005 to October 2010. The registered patients were divided into two groups; young age group (<65 years) and old age group (≥65 years).</P><P><B>Results</B></P><P>The young age group included 5281 patients (age, 53±7.8 years), and the old age group included 4896 patients (age, 74.3±6.5 years). Male gender, smoking, family history, dyslipidemia, and metabolic syndrome were more frequently observed in the young age group than in the old age group (89.5% vs. 59.3%, p<0.001; 77.3% vs. 47.2%, p<0.001; 11% vs. 4.6%, p<0.001; 11.2% vs. 7.7%, p<0.001; 67.6% vs. 62.9%, p<0.001). Most of the young Korean adults with STEMI complained of typical chest pain (89.8%), and they had a shorter symptom-to-door time (12±53.2 hours vs. 17.3±132 hours, p=0.010). The young age group showed a favorable prognosis, which was represented by the MACE, compared with the old age group at one month (1.8% vs. 2.8%, p=0.028), six months (6.8% vs. 8.2%, p<0.001), and twelve months (10.1% vs. 11.9%, p=0.025). However, there was no significant difference in the adjusted MACE rate at one month {hazard ratio (HR) 0.95, 95% confidence interval (CI) 0.60-1.51, p=0.828} and twelve months (HR 0.86, 95% CI 0.68-1.10, p=0.233).</P><P><B>Conclusion</B></P><P>Younger Korean adults with STEMI have clinical outcomes similar to old aged patients, and therefore, they should be treated intensively like the elderly patients.</P>