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      • 자동차 차체 다점용접부의 면외변위측정에 관한 연구

        차용훈,성백섭,이연신,박영문,김충환 朝鮮大學校 機械技術硏究所 2002 機械技術硏究 Vol.5 No.1

        The very few non-contact method are still in the early stage. One of the non-contact methods is by the use of the laser that has high-level of the accuracy for the measurement, and this laser also has excellent characteristics on which many studies for its applications are focused throughout the many fields. The dissertation is on the measurement of the strain caused by the characteristics of the spot welded zone which is used with 3-D ESPI system that is functionally modified through the laser ESPI(Electronic Speckle Pattern Interferometry) system. This system employed the SGCC 1.2t which are mainly used for the steel plate such as automobile, structure, electronics instrument, building material and electronic appliances.

      • 로봇 아크용접의 용접조건 신뢰성 평가

        차용훈,성백섭,박영문 朝鮮大學校 機械技術硏究所 2001 機械技術硏究 Vol.4 No.2

        This paper describes to realize the mapping characteristics of bead height through learning. After learning, the neural estimation can estimate the bead height desired from the learning mapping characteristic. The design parameters of the neural network estimator(the number of hidden layers and the number of nodes in a layer) are choosen from an estimation error analysis. A series of bead of bead-on-plate GMA welding experiments was carried out in order to verify the performance of the neural network estimator. The experimental results show that the proposed neural network estimator can predict the bead height with reasonable accuracy and guarantee the uniform weld quality.

      • 동측 대퇴골 및 경골 간부 골절의 치료

        유문집,차응남,김용민 동국대학교 경주대학 1993 東國論集 Vol.12 No.-

        Multiple fractures are becoming increasing due to traffic and industrial developments. Ipsilateral femur and tibia fractures are caused by high energy trauma and associated with many problems such as hemorrhagic shock, longer morbidity, delayed union of nonunion, knee stiffness etc. Recently the principles of treatment are directed to rigid internal fixation and early mobilization for more satisfactory functional recovery. Since July 1990, we managed 6 patients who had ipsilateral femur and tibia shaft fractures mainly with intramedullary nailing. The results are as follows ; 1. All the 6 cases were accompanied by multiple fractures and/or dislocations. Ipsilateral knee injuries were combined in 2 cases. 2. As for the femur, intramedullary nails were used in all cases. Intramedullary nailing was used for the tibia in 5 cases, and external skeletal fixator in the other one. 3. All the fractures united. Union time of the femoral fractures ranged from 6 to 8 months(mean : 29 weeks ; 6.7 months). Tibia shaft fractures united at from 14 to 32 weeks(mean : 22 weeks ; 5.2 months) postoperatively. 4. 3 Knees recovered full range of motion. But in the other 3 knees, limitations of further flexion to average 100 degrees were noted.

      • KCI등재

        환경친화형 수분산성 불소 아크릴레이트 공중합체에 의한 섬유 표면개질

        유수용,김정두,문명준,서차수,주창식,이민규 한국환경과학회 2004 한국환경과학회지 Vol.13 No.10

        Waterborne fluorinated acrylate copolymer (WFAC) for surface modification of textile was synthesized from perfluoroalkyl ethyl acrylate, octadecyl acrylate, glycidyl methacrylate, surfactant and 3,3 methyl-methoxy butanol. The structures of the synthesized WFAC were determinated by FT-IR and ^(19)F-NMR analysis. The thermal stability investigated with DSC and TGA was decreased with increasing the content of fluorinated acrylate in the copolymer. However, the particle sizes of WFAC were increased with increasing the content of fluorinated acrylate in the copolymer. The surface energies calculated by contact angles of WFAC were in the range of 29.80~3.41 dyne/cm. On the observing SEM of the textile surface treated with WFAC, the textile was swollen and compacted with increasing the concentration of water repellency agent. WFAC synthesized in this study showed a good water repellency.

      • 토끼의 Aflatoxin B₁중독증에 대한 인삼엑기스의 효과 : 임상, 생리적 및 병리학적 변화 Clinical, Physiological and Pathological Changes

        김차용,변유성,문평일,정덕화,김종수 慶尙大學校 1987 論文集 Vol.26 No.1

        Chinchilla 계통 1~1.5㎏ 되는 토끼 30마리를 5군 으로 나누어 체중㎏당 제 1군은 대조군으로서 Cornoil 0.3ml 씩 제 2군은 aflatoxin B? 0.03mg과 인삼 엑기스 8mg을 제 5군은 aflatoxin B? 0.06mg과 인삼엑기스 8mg을 3주동안 카테타로 경구 투여하여 임상, 혈액학적 및 병리학적 변화를 관찰하였다. 1.사료소비량 감소, 침울, 쇠약, 혼수, 체중증가율감소등과 같은 임상증상은 대조군을 제외한 전 처리군에서 독을 투여후 3일째 부터 전처리기간을 통하여 나타났으나 aflatoxin B? 단독처리군에서 인삼엑기스 혼합처리군보다 더 현저하게 나타났다. 2. 혈청 효소와 AST, ALT는 독물투여후 7일부터 인삼엑기스 혼합투여군 보다 aflatoxin B? 단독 투여군에서 높게 증가하였다. 3.전처리군에서 적혈수용적, 헤모글로빈농도는 영향을 받지 않았고, 혈장단백질은ㅇ 독물투여후 14일이후 aflatoxin B?단독 처리군에서 현저하게 감소하였다. 4. Aflatoxin B?과 인삼엑기스 혼합 투여군 보다 aflatoxin B? 단독투여군에서 간장의 공포변성,담관증생, 핵농축, 붕괴, hepatic fibrosis와 임파절 및 비장에서 현저한 임파양 세포의 소실을 나타내었다. The present study has been carried out to investigate the effectsof ginseng extract on induced chronic aflatoxicosis in rabits. Groups of rabbits were treated orally with aflatoxin B? and mixture of ginseng extract for 21 days with a dosage of 0.03mg, 0.06mg of the toxin and 0.03mg or o.o6mg of the toxin mixture of 8mg of ginseng extract or 0.3ml corn oil s place to per kg body weight. The results obtained were is follows. 1. Sings o toxicosis included reduction of feed consumption emaciation, decrese of body weight and coma revealed in both groups treated with 0.03mg pr 0.06,mg of aflatoxin B?/Kg/B.W than groups 4.5 after days 3. 2. In groups 2, 3(aflatoxin B? 0.03, 0.06mg), Activity of asparate aminotransferase(AST) and alanine aminotransferase (ALT)were increased sigificantly in dats7, 14 and 21. 3. In all groups, Mean values for packed cell volume(PCV)and hemogobin were unremarkasble, but plasma total protein were decreased in groups 2,3than 4,5 groups on days 14 and 21. 4. The rabits treated with aflatoxin B?(2,3 groups)showed markedly degenerative chasnges ranging from swelling and decreaseed granularity to marked vacuolation, hepatic necrosis, fibrosis and bile duct, Proliferation and depletion of lymphocytes in lymphocytes in lymphonde, spleen than groups 4,5.

      • 급성 구강감염부위에서 Staphylococcus lugunensis 의 특성

        유용욱,이미성,차정단,김기경,신상희,문상은,김강주 원광대학교 생명공학연구소 1999 생명공학연구소보 Vol.6 No.1

        Staphylococcus lugdunensis (S. lugdunensis) is a newly identified pathogenic species of coagulase negative staphylococci and an occasional but not rare cause of severe infections, such as infective endocarditis after dental extraction, bacteremia, osteomyelitis, peritonitis, and soft tissue infections. As antibiotic use increased, resistance rapidly developed. Some strains have plasmids related to antibiotic resistance. To characterize S. lugdunensis in acute oral infection, S. lugdunensis was isolated from the patients with acute oral abscess, osteomyelitis, and normal persons. Antibiotic resistance, in vitro cellular toxicity, in vivo virulence, δ-like hemolysin activity, and synergistic hemolysis on sheep blood agar plates were investigated. The dot blot analysis and Southern blot analysis of staphylococcal DNA was performed with δ-hemolysin gene probe of Staphylococcus aureus. (S. aureus) Staphylococcal DNA was cloned, nucleotide sequence was analysed, and homology was compared with other sequence in Gene Bank. S. aureus, S. lugdunensis, Staphylococcus cohnii (S. cohnii), and other coagulase negative staphylococci (CNS) were isolated from the patients with acute oral infection. The isolation ratio of S. lugdunensis in the patients with infection was higher than that of healthy persons, but the isolation ratio of S. aureus in the patients with infection was similar to that of healthy persons. S. lugdunensis from the patients with acute oral infection showed the resistance to penicillin, methicillin, cephalothin, and clindamycin. S. lugdunensis in the patients had cellular toxicity in vitro and virulence in vivo. All strains of S. lugdunensis had δ-like hemolysin activity against rabbit erythrocytes. Four of the six strains of S. lugdunensis gave synergistic hemolysis with S. aureus on sheep blood agar plates. In dot blot analysis, all strains of S. lugdunensis showed the positive reaction with the probe of δ-hemolysin gene in S. aureus, but a 7.3 kb HindⅢ fragment was observed in the DNA of S. lugdunensis that gave synergistic hemolysis in a Southern blot analysis. The molecular size of partially purified δ-hemolysin was about 50 kd. The cloned fragments from the chromosomal DNA of S. lugdunensis showed the partial homology with the insulin receptor-related and dopamine receptor of humans. These results suggest that S. lugdunensis might be an important pathogen in acute oral infection and show some homology with eukaryotes.

      • 진주담치 濃縮엑스분의 製造 및 利用

        李應昊,具在根,車庸準,文聖勳 釜山水産大學校 1983 釜山水産大學 硏究報告 Vol.23 No.2

        진주담치 乾製品, 製造時 副産物로 생성되는 엑스분을 食品加工用 中間素材로서의 이용가능성을 검토하고자 진주담치 濃縮엑스분을 製造하였으며 그 製品의 化學成分 및 重金屬含量을 分析하였다. 그리고 용도개발 實驗을 하여 다음과 같은 결과를 얻었다. 1. 진주담치를 98℃에서 20分間 蒸煮하여 生成된 엑스분을 93℃에서 4時間 동안 이중솥에서 paste狀으로 될 때까지 濃縮한 결과 製品의 수율은 5.8%였으며, 製品의 水分含量은 42.8%였고, 乾物量 基準으로 粗蛋白質은 32.7%, 글리코겐은 4.8%, 무기질은 31.6%였다. 그리고 pH는 5.16, VBN은 67mg/100mg이었다. 2. 濃縮엑스분 製品의 遊離 아미노산 含量은 全엑스분 室素의 71.4%를 차지하였으며, glycine, arginine, alanine, phenylalanine, lysine, tyrosine, histidine, methionine 및 leucine의 9종의 아미노酸이 總아미노酸의 89.6%를 차지하였다. 3. 용도개발 목적으로 인스탄트 면류 조미수우프 및 크림수우프를 만들어 市販 수우프류를 對照製品으로 官能檢査한 결과 거의 손색이 없었으며 패류 특유의 시원한 맛이 있었다. 그리고 重金屬 含量도 극미량으로 진주담치 濃縮엑스분 製品은 食品衛生上의 安全性이나 營養面에 있어서 손색이 없고 天然香味를 지닌 우수한 食品加工用 中間素材로 利用가능하다는 結論을 얻었다. In order to utilize extracts which are produced as a by-product when dried sea mussel products are processed, concentrated extracts of sea mussel was prepared and its chemical composition, quality stability and effective methods of its utilization are examined. 1. After the sea mussel was steamed at 98℃ for 20min, extracts was concentrated as a paste state in a double jacketed cooker at 93℃ for 4 hrs. 2. The yield of concentrated extracts of sea mussel was 5.8%, and the content crude protein was 32.7%, glycogen 4.8%, minerals 31.6%, VBN 66.87mg % and heavy metals (Pb, Cd, Hg, Cu, Zn) were trace in content. 3. The content of total free amino acids of the product was 71.4% of total extractive nitrogen and the abundant contents of amino acid in the product were glycine, arginine, alanine, phenylalanine, lysine, tyrosine, histidine, methionine, leucine. Judging from sensory evaluation, the instant noodle soup and cream soup made from concentrated extracts of sea mussel were not inferior to the control which purchased on the market.

      • SCOPUSKCI등재

        The role of mitochondrial DNA mutation on neurodegenerative diseases

        Cha, Moon-Yong,Kim, Dong Kyu,Mook-Jung, Inhee Nature Publishing Group 2015 Experimental and molecular medicine Vol.47 No.3

        <P>Many researchers have reported that oxidative damage to mitochondrial DNA (mtDNA) is increased in several age-related disorders. Damage to mitochondrial constituents and mtDNA can generate additional mitochondrial dysfunction that may result in greater reactive oxygen species production, triggering a circular chain of events. However, the mechanisms underlying this vicious cycle have yet to be fully investigated. In this review, we summarize the relationship of oxidative stress-induced mitochondrial dysfunction with mtDNA mutation in neurodegenerative disorders.</P>

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