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Bhardwaj, Neha,Bhardwaj, Sanjeev,Mehta, Jyotsana,Kim, Ki-Hyun,Deep, Akash Elsevier 2016 Biosensors & bioelectronics Vol.86 No.-
<P><B>Abstract</B></P> <P>The sensitive detection of dipicolinic acid (DPA) is strongly associated with the sensing of bacterial organisms in food and many types of environmental samples. To date, the demand for a sensitive detection method for bacterial toxicity has increased remarkably. Herein, we investigated the DPA detection potential of a water-dispersible terbium-metal organic framework (Tb-MOF) based on the fluorescence quenching mechanism. The Tb-MOF showed a highly sensitive ability to detect DPA at a limit of detection of 0.04nM (linear range of detection: 1nM to 5µM) and also offered enhanced selectivity from other commonly associated organic molecules. The present study provides a basis for the application of Tb-MOF for direct, convenient, highly sensitive, and specific detection of DPA in the actual samples.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Dipicolinic acid (DPA) is an excellent indicator of bacterial infection. </LI> <LI> In this work, metal organic frameworks (MOFs) are explored as potential DPA detectors. </LI> <LI> Fluorescent detection of DPA is achieved by synthesizing the Tb-MOF ‘Tb(BTC)(H<SUB>2</SUB>O)<SUB>6</SUB>’. </LI> </UL> </P>
Bhardwaj, Sanjeev K.,Bhardwaj, Neha,Kaur, Rajnish,Mehta, Jyotsana,Sharma, Amit L.,Kim, Ki-Hyun,Deep, Akash The Royal Society of Chemistry 2018 Journal of Materials Chemistry A Vol.6 No.31
<P>Metal-organic frameworks (MOFs) are known to possess many interesting material properties such as high specific surface area, tailorable porosity, adsorption/absorption capabilities, post-synthetic modifications, and chemical/thermal stabilities. Because of these unique features, they have been explored for the development of sensors for a variety of analytes. A large proportion of pre-existing MOF-based sensors are well suited for optical transductions due to a lack of electrical conduction in their pristine forms. Hence, the development of MOF-based electrochemical/electrical sensors requires specialized strategies through which MOFs are modified or hybridized with enhanced conductive moieties (<I>e.g.</I>, <I>via</I> doping or post synthetic modification). In this review article, we provide a comprehensive review of various synthetic and integrating strategies to improve electrical conductivity and long-range charge transport properties in MOFs. To this end, we have compiled details of different techniques that have been used to develop electrically/electrochemically active platforms for MOF-based sensing of various targets.</P>
Bhardwaj, Neha,Bhardwaj, Sanjeev K.,Mehta, Jyotsana,Kim, Ki-Hyun,Deep, Akash American Chemical Society 2017 ACS APPLIED MATERIALS & INTERFACES Vol.9 No.39
<P>To produce a sensitive and specific biosensor for Staphylococcus aureus, bacteriophages have been interfaced with a water-dispersible and environmentally stable metal-organic framework (MOF), NH2-MIL-53(Fe). The conjugation of the MOF with bacteriophages has been achieved through the use of glutaraldehyde as cross-linker. Highly sensitive detection of S. aureus in both synthetic and real samples was realized by the proposed MOF-bacteriophage' biosensor based on the photoluminescence quenching phenomena; limit of detection (31 CFU/mL) and range of detection (40 to 4 X 10(8) CFU/mL). This is the first report exploiting the use of an MOF-bacteriophage complex for the biosensing of S. aureus. The results of our study highlight that-the proposed biosensor is more sensitive than most of the previous methods while exhibiting some advanced features like specificity) regenerability, extended range of linear 'detection, and stability for long-term storage (even at room temperature).</P>
Fluorescent nanobiosensors for the targeted detection of foodborne bacteria
Bhardwaj, Neha,Bhardwaj, Sanjeev K.,Nayak, Manoj K.,Mehta, Jyotsana,Kim, Ki-Hyun,Deep, Akash Elsevier 2017 Trends in analytical chemistry Vol.97 No.-
<P>Foodborne diseases caused by bacterial pathogens are severe threats to human health. Conventional culture based microbiologic methods for the analysis of bacterial contamination in food products are laborious, time consuming and require specific skills. Immunologic and polymerase chain reaction (PCR) based molecular methods are also costly, lack specificity, and may yield false results. As outlined in this review, fluorescent nanobiosensors have now become effective alternative tools for rapid and routine detection of foodborne bacteria. We provide an overview of the use of different fluorescent nano materials in the development of nanobiosensors with special emphasis on underlying detection principles, sensitivity, specificity, and their capability of multiplexed analysis. In summary, the diverse nanomaterials used for bacterial detection are critically analyzed with respect to their advantages and limitations for future applications in the diagnosis of foodborne bacteria. (C) 2017 Elsevier B.V. All rights reserved.</P>
Nishi K. Bhardwaj,Nishi K. Bhardwaj,Surendra P. Singh 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.22 No.-
Recycled pulp contains large amount of fines having high surface area and amorphous cellulose. Thesefines adsorb water to large extent and dewatering rate is lower compared to virgin pulp. Selectivehydrolysis of these excess ultra fines through cellulase enzymes can be utilized for enhancing thedrainage rate. The concept of monocomponent cellulase treatment of recycled pulp for improvement indrainage and the understanding whether effectiveness depends on a specific type of cellulasecomponent (endoglucanase/cellobiohydrolase) is described. The improvement of 15–23% in pulpdrainability was achieved along with better paper properties.
On the Minimization of Crosstalk Conflicts in a Destination Based Modified Omega Network
Bhardwaj, Ved Prakash,Nitin, Nitin Korea Information Processing Society 2013 Journal of information processing systems Vol.9 No.2
In a parallel processing system, Multi-stage Interconnection Networks (MINs) play a vital role in making the network reliable and cost effective. The MIN is an important piece of architecture for a multiprocessor system, and it has a good impact in the field of communication. Optical Multi-stage Interconnection Networks (OMINs) are the advanced version of MINs. The main problem with OMINs is crosstalk. This paper, presents the (1) Destination Based Modified Omega Network (DBMON) and the (2) Destination Based Scheduling Algorithm (DBSA). DBSA does the scheduling for a source and their corresponding destination address for messages transmission and these scheduled addresses are passed through DBMON. Furthermore, the performance of DBMON is compared with the Crosstalk-Free Modified Omega Network (CFMON). CFMON also minimizes the crosstalk in a minimum number of passes. Results show that DBMON is better than CFMON in terms of the average number of passes and execution time. DBSA can transmit all the messages in only two passes from any source to any destination, through DBMON and without crosstalk. This network is the modified form of the original omega network. Crosstalk minimization is the main objective of the proposed algorithm and proposed network.
वर्तमान भारतीय समाज के प्रमुख द्वंद्व और चुनौतियां
??????? ????????(Bhardwaj, Virender) 한국외국어대학교 인도연구소 2009 남아시아연구 Vol.15 No.1
Every age in human history has tried to find out the solution of its contemporary problems in its mythological texts. They have always worked as the mirror of the age and society. The Modern Hindi literature is full of such examples. The social set up in 21<SUP>st</SUP> century in india is surrounded with the conflicts and challenges which are in nature quite comparable to the conflicts and the challenges that existed during the Mahabharata period in the society. Some of the problems in present time have become far more serious and pose great threat to the unifying code of Indian society. The present paper tries to examine some major social, political. cultural and even religious issues with which the whole Indian Society seems to be fighting, There are quite a number of literary works in Hindi poetry that are very much influenced by Mahabharata and many such other epics in India, The major Hindi literary works(poetry in particular) that can be listed in this context are, ‘kurukshetra’, ‘rashmirathi’ ‘andhayuga’, ‘mahaprashathana’, ‘senapatikaran’ and ‘droupadi’ etc, The main thread that tied up these literary works(poetry) together like a garland shows how the hopelessness and disappointment crept in the very thinking of the intellectual people of India in 21<SUP>st</SUP> Century, This century has witnessed hundreds of research works that have engaged with ‘Dalit vimarsha’ and ‘Nari vimarsha’. The present paper is an attempt and effort to examine the above mentioned conflicts that resulted in the following catastrophic forms in the contemporary Indian literature: a, The major concerns of ‘Dalit vimarsha’ and ‘Nari vi marsha’ b. The Indian social stratification system that was based on the work got settled later on the basis of the birth c. The loss of the importance of duties(karma) d. The purposeful protection of the ‘cast and religion’ based division of the society for Politicians’ self-interest e. Distancing of the society from the values of ‘faith’, ‘truth’, ‘non-violence’, ‘equality’, ‘sacrifice’, ‘nationalism’, ‘prestige’ and ‘policy’(niti) f. Unawareness of the impact of colonialism g. The marathon for the possession of Nuclear weapons Having examined the above mentioned issues in the historical context of modern Hindi poetry, the paper also tries to establish the virtue of the system in 21<SUP>st</SUP> Century in India that can be made on the basis of the deeds (karma). The paper also provides a platform to correlate the ancient and modern thinking and paves the path that can help and lead to various other kind of research and it can be done on the other mythological texts of India subcontinent.
Inclusive and exclusive measurements ofBdecays toχc1andχc2at Belle
Bhardwaj, V.,Miyabayashi, K.,Panzenbö,ck, E.,Trabelsi, K.,Frey, A.,Abdesselam, A.,Adachi, I.,Aihara, H.,Al Said, S.,Arinstein, K.,Asner, D. M.,Atmacan, H.,Aulchenko, V.,Aushev, T.,Ayad, R.,Babu, V American Physical Society 2016 Physical Review D Vol.93 No.5
<P>We report inclusive and exclusive measurements for chi(c1) and chi(c2) production in B decays. We measure B(B -> chi X-c1) = (3.03 +/- 0.05 (stat) +/- 0.24(syst)) x 10(-3) and B(B -> chi X-c2) = (0.70 +/- 0.06 (stat) +/- 0.10(syst)) x 10(-3). For the first time, chi(c2) production in exclusive B decays in the modes B-0 -> chi(c2) pi K--(+) and B-0 -> chi(c2) pi(-)pi K-+(+) has been observed, along with first evidence for the B-0 -> chi(c2) pi K--(s)0 decay mode. For chi c1 production, we report the first observation in the B+ -> chi(c1) pi(-)pi K-+(+), B-0 -> chi(c1) pi(-)pi K-+(s)0 and B-0 -> chi(c1) pi(-)pi K-+(+) decay modes. Using these decay modes, we observe a difference in the production mechanism of chi(c2) in comparison to chi(c1) in B decays. In addition, we report searches for X(3872) and chi(c1) (2P) in the B+ -> (chi(c1) pi(+)pi(-))K+ decay mode. The reported results use 772 x 10(6) B (B) over bar events collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider.</P>
Search for X(3872) and X(3915) decay into χc1π0 in B decays at Belle
Bhardwaj, V.,Jia, S.,Adachi, I.,Aihara, H.,Asner, D. M.,Aushev, T.,Ayad, R.,Babu, V.,Badhrees, I.,Bahinipati, S.,Bansal, V.,Behera, P.,Beleñ,o, C.,Berger, M.,Bhuyan, B.,Bilka, T.,Biswal, J.,Bobr American Physical Society 2019 Physical review. D Vol.99 No.11