Room temperature quantum key distribution characteristics of low-noise InGaAs/InP single-photon avalanche diode

Baek Soo-Hyun,Yang Seung-Chul,Park Chan-Yong,Park Chul-Woo,Cho Seok-Beom,Ryu Sang-Wan 한국물리학회 2021 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.78 No.7

InGaAs/InP single-photon avalanche diode (SPAD) with small active diameter and backside microlens was fabricated and its dark count and after-pulse noises were characterized. In addition, by optimizing multiplication layer and reducing the active diameter, high photon detection efficiency (PDE) was achieved as well as suppressed dark count probability (DCP) and after-pulse probability (APP) near room temperature. The gated Geiger-mode characteristics of SPAD were investigated with the gate amplitude of 6.6 V and repetition frequency of 10 MHz. Superior single-photon detection characteristics as PDE of 20.9%, DCP of 1.02 × 10– 5 and APP of 0.8% were observed at the operation temperature of + 20 °C. It is a promising result that allows compact and low-cost detector module for quantum key distribution system with simple cooling apparatus.

An NMR Study on the Conformation of Substance P in Acidic Bicelles

Baek, Seung-Bin,Lim, Sung-Chul,Lee, Hyeong-Ju,Lee, Hee-Cheon,Kim, Chul Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.10

The conformation of a neuropeptide, substance P (SP), in isotropic (q = 0.5) acidic bicelles was investigated using two-dimensional NMR techniques. By the nuclear Overhauser effect (NOE) cross peaks between SP and long-chain lipid molecules SP was probed to bind on the flat surface of the disc-like bicelles. Structural analysis of NMR data indicated that the helical conformation of SP extended to the C-terminal region of Leu10 as well as in the mid-region from Pro4 to Phe8. As compared with the conformations of SP bound on the sodium dodecylsulfate (SDS) or the dodecylphosphocholine (DPC) micelles with curved surfaces, the surface curvature of the membrane mimics was found to be one of the major factors inducing the biologically relevant conformation of SP. The negative surface charge of the membrane is also a key factor inducing both the binding of SP on the membrane and its biologically active structure.

Apparent seed quality and climatic factors during reproductive stage in soybean

Sang-Ouk Shin,Seong-Hyu Shin,Tae-Joung Ha,Sea-Gyu Lim,Kyung-Jin Choi,In-Yeul Baek,Keum-Yong Park,Sang-Chul Lee 한국작물학회 2008 한국작물학회 학술발표대회 논문집 Vol.2008 No.10

This experiment was carried out to examine seed quality as affected by enviromental cutivation for the production of high quality domestic soybean variety at Miryang (altitude : 12m) and Muju(altitude : 600m). Variety used were Daewon, Daepung, Daol and Cheongja 3. Seeding was performed on April 30 to June 30 and planting density was 142,857 palnts/ha. Seed weight across regions was lighter as seeding date was delayed. Opposite trends between seed crack and seed weight was obtained. Seed crack decreased as seeding date was delayed and have higher occurrence in Miryang than in Muju. Perple seed and phomopsis decayed seed decreased as seeding date was delayed. There was a significant negative correlation between seed weight and mean temperature from R2 to R4 stages in all variety. Seed weight increased as mean temperature from R2 to R4 stage decreased to 22.0℃, which was greatly manifested on Daewon variety. At maturity time, Daewon variety had an average increase of 1.79g as mean temperature decreased by 1℃. Seed weight of Daewon obtained a significant negative correlation with mean temperature at R4~R6 stage and on rainfall at R4~R6 stage. Mean temperature and rainfall were able to estimate 100 seed weight of Daewon and Daepung variety with 98.1% and 96.6% probability, respectively. Phomopsis occurrence in late maturity type was closely related to rainfall during the R4~R6 stages.

Recurrence of Small Cerebral Aneurysms (< 4 mm) Treated Endovascularly Using Target® NanoTM Coils

Sung Min Kim,Hyun Gon Lee,Byung Sam Choi,Jung Soo Kim,Sungjoon Lee,Hae Yu Kim,Sung Tae Kim,Young-Gyun Jeong,Jin Wook Baek,Hae Woong Jeong,Sung-Chul Jin 대한뇌혈관외과학회 2018 Journal of Cerebrovascular and Endovascular Neuros Vol.20 No.2

Objective : In our series, endovascular coiling with Target® NanoTM coils (Stryker Neurovascular, Fremont, CA, USA) with diameters of 1 or 1.5 mm exhibited favorable technical feasibility in the treatment of small cerebral aneurysms (< 4 mm). However, little is known about the recurrence of small cerebral aneurysms treated using Target® NanoTM coils. We investigated recurrence following the treatment of small cerebral aneurysms using Target® NanoTM coils. Materials and Methods : Between January 2012 and November 2013, 143 patients with 148 small cerebral aneurysms (< 4 mm) were included our study. A total of 135 cerebral aneurysms (91.2%) were unruptured; 45 cerebral aneurysms (30.4%) were treated by endovascular coiling using Target® NanoTM coils. Follow-up radiological images were obtained for 132 cerebral aneurysms (89.2%) over a range of 3 to 58 months (mean, 34.3 months; standard deviation, 14.2). Results : In the group treated with Target® NanoTM coils, radiological outcomes revealed complete occlusion in 33 (73.3%), residual necks in eight (17.8%), and residual sacs in four (8.9%) cases. Follow-up radiological outcomes revealed complete occlusion in 35 (77.8%) and residual necks in four (8.9%) cases that exhibited stable coil masses. In the group that was not treated with Target® NanoTM coils, radiological outcomes revealed complete occlusion in 69 (67%), residual necks in 18 (17.5%), and residual sacs in 16 (15.5%) cases. Follow-up radiological outcomes revealed complete occlusion in 87 (84.5%) and residual necks (5.8%) in six cases that exhibited stable coil masses. No significant differences were observed in the radiological outcomes or follow-up radiological outcomes between the two groups. No recurrences or retreatments occurred in our series. Conclusion : Endovascular treatment using Target® NanoTM coils may be a robust treatment option for small cerebral aneurysms (< 4 mm).

Correlation between contrast leakage period of procedural rupture and clinical outcomes in endovascular coiling for cerebral aneurysms

Sung Tae Kim,Sung-Chul Jin,Hae Woong Jeong,Jin Wook Baek,Young Gyun Jeong 대한뇌혈관외과학회 2023 Journal of Cerebrovascular and Endovascular Neuros Vol.25 No.4

Objective: Intraprocedural rupture (IPR) is a fatal complication of endovascular coiling for cerebral aneurysms. We hypothesized that contrast leakage period may be related to poor clinical outcomes. This study aimed to retrospectively evaluate the relationship between clinical outcomes and contrast leakage period.Methods: Data from patients with cerebral aneurysms treated via endovascular coiling between January 2010 and October 2018 were retrospectively assessed. The enrolled patient’s demographic data, the aneurysm related findings, endovascular treatment and IPR related findings, rescue treatment, and clinical outcome were analyzed.Results: In total, 2,859 cerebral aneurysms were treated using endovascular coiling during the study period, with IPR occurring in 18 (0.63 %). IPR occurred during initial frame coiling (n=4), coil packing (n=5), stent deployment (n=7), ballooning (n=1), and microcatheter removal after coiling (n=1). Tear sites included the dome (n=14) and neck (n=4). All IPRs were controlled and treated with coil packing, with or without stenting. Flow arrest of the proximal balloon was not observed. Temporary focal neurological deficits developed in two patients (11.1%). At clinical follow-up, 14 patients were classified as modified Rankin Scale (mRS) 0, three as mRS 2, and one as mRS 4. The mean contrast leakage period of IPR was 11.2 min (range: 1-31 min). Cerebral aneurysms with IPR were divided into late (n=9, mean time: 17.11 min) and early (n=9, mean time: 5.22 min) control groups based on the criteria of 10 min of contrast leakage period. No significant between-group differences regarding clinical outcomes were observed after IPR (p=1).Conclusions: In our series, all patients with IPR were controlled with further coil packing or stenting without proximal balloon occlusion within 31 min of contrast leakage. There was no difference in clinical outcomes when the long contrast leakage period group and short contrast leakage period group were compared.

Effect of Liver Transplantation on Glucose Levels in Patients with Prediabetes or Type 2 Diabetes

Sang In Bae,Jae Do Yang,Hong Pil Hwang,Sun Hee Kim,Jae Moon Kim,Kyung Ae Lee,Tae Sun Park,Hong Sun Baek,Heung Yong Jin,Baek Hwan Cho,Hee Chul Yu 한국간담췌외과학회 2014 한국간담췌외과학회 학술대회지 Vol.2014 No.4

Metformin enhanced chemoresistance of human malignant mesothelioma cells cultured in glucose deprived media

Sung Hyun Hwang,Myung Chul Kim,Na yon Kim,Hong Seok Lee,Yong baek Kim 대한수의학회 2016 대한수의학회 학술대회발표집 Vol.2016 No.-

Risk factors for locoregional recurrence in patients with pathologic T3N0 rectal cancer with negative resection margin treated by surgery alone

Baek, Jong Yun,Yu, Jeong Il,Park, Hee Chul,Choi, Doo Ho,Yoo, Gyu Sang,Cho, Won Kyung,Lee, Woo-Yong,Yun, Seong Hyeon,Cho, Yong Beom,Park, Yoon Ah,Kim, Hee Cheol The Korean Society for Radiation Oncology 2019 Radiation Oncology Journal Vol.37 No.2

Purpose: This study aimed to identify prognostic factors for locoregional recurrence (LRR) in pT3N0 rectal cancer patients who were treated with surgery alone and had negative resection margin including circumferential resection margin (CRM) for optimal indication of adjuvant radiotherapy. Materials and Methods: We reviewed patients with pT3N0 rectal cancer who were treated via upfront surgery and had no other adjuvant treatment from January 2003 to December 2012. In total, 122 patients who had negative resection margin including negative CRM were included in the analysis. Results: The median follow-up period after surgery was 60 months (range, 3 to 161 months). During this time, 6 patients (4.9%) experienced LRR at the anastomotic site (4 patients), and regional lymphatic area (2 patients). The estimated 5-year rates of overall survival, recurrence-free survival, and LRR-free survival were 96.7%, 84.6%, and 94.0%, respectively. Multivariate analysis showed that level of tumor ≤5 cm was a significant prognostic factor for LRR-free survival (LRRFS) (p = 0.04; hazard ratio = 7.08; 95% confidence interval, 1.06-47.30). Patients with level of tumor ≤5 cm had an estimated 5-year LRRFS of 66.8%, which was much higher than 2.3% in patients with level of tumor >5 cm. There was no significant factor for recurrence-free survival or overall survival. Conclusion: In T3N0 rectal cancer, adjuvant chemoradiotherapy should be recommended in patients with level of tumor ≤5 cm for better local control. However, in patients with pT3N0 disease, negative resection margin, and level of tumor >5 cm, adjuvant chemoradiotherapy should be carefully suggested.

A New Large Seed Size, Good Seed Quality and High-Yielding Vegetable Soybean Cultivar "Danmiput"

Sung Taeg Kang,In Youl Baek,Myoung Gun Choung,Sea Kwan Oh,Won Young Han,Doo Chull Shin,Su Dong Kim,Soon Chul Kim 한국육종학회 2003 한국육종학회지 Vol.35 No.4

A new vegetable soybean variety, “Danmiput” was selected from the cross Keunol/Wasehakucho (Introduced), and developed in 2002 on the basis of its yield performance and seed quality for vegetable soybean at the National Yeongnam Agricultural Station. “Dan

Effects of Dietary Supplementation of a New Probiotic CS61 Culture on Performance in Broiler Chickens

Sung-Hwan Kim(김성환),In-Chul Lee(이인철),Hyung-Seon Baek(백형선),Seong-Soo Kang(강성수),Hyoung-Chin Kim(김형진),Jin-Cheol Yoo(유진철),Jong-Choon Kim(김종춘) 한국생명과학회 2012 생명과학회지 Vol.22 No.3

가금류 제품에서 항생제의 잔류와 내성균의 출현으로 인해 항생제 대체물질에 대한 연구가 활발히 진행되고 있으며, 특히 생균제와 활성촉진제 또는 이들을 조합한 신바이오틱의 사용이 권장되고 있다. 본 연구는 새로운 생균제 CS61 배양액의 사료첨가 급여가 육계의 성장 및 사료효율에 미치는 영향과 안전성을 평가하여 항생제를 대체할 수 있는 사료첨가제로서의 개발가능성을 알아보기 위해 수행하였다. CS61 배양액은 0, 0.1 및 1%의 용량으로 28일간 사료에 혼합하여 육계에게 급여하였다. 시험결과, 시험물질 처치군에서 부검 시의 체중과 일당증체량이 대조군에 비해 용량의존적으로 증가하였다. CS61 배양액의 사료 내 첨가는 대조군 동물에 비해 사료효율도 개선하는 것으로 나타났다. 반면, 일반증상과 사망률, 부검소견, 혈액학치 및 혈청생화학치에서는 시험물질의 처치와 관련된 독성소견이 관찰되지 않았다. RAW 264.7 세포를 이용한 일산화질소 시험에서 정제된 CS61 펩타이드는 lipopolysaccharide에 유도된 일산화질소 생성을 용량의존적으로 억제하였다. 본 시험결과는 육계에 CS61 배양액의 사료첨가 급여는 항염증효과를 통해 성장과 사료효율을 개선할 수 있음을 보여주며, 사료첨가제로서 CS61 배양액의 유용성과 개발가능성을 시사해 주고 있다. Bacterial resistance to antibiotics and residues of antibiotics in poultry products have encouraged the use of probiotics, prebiotic substrates, and synbiotic combinations of prebiotics and probiotics as alternative approaches to the use of antibiotics in poultry. The present study was carried out to evaluate the effect of a new probiotic CS61 culture on growth performance, feed conversion efficiency, and safety in broiler chickens, and to evaluate its value as an alternative for antibiotics used as a feed additive. Two dosages of CS61 culture (0.1% and 1%) were fed to chickens for 28 days. The results showed that terminal body weight and daily weight gain in the treatment groups increased in a dose-dependent manner when compared with the control group. Dietary supplementation with CS61 culture also improved feed conversion rate compared to the control group. There were no treatment- related toxic effects in terms of clinical findings, mortality, necropsy findings, hematology, or serum biochemistry parameters in any group tested. The nitric oxide assay showed that CS61 peptide has a dose-dependent inhibitory effect on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells. The results of this experiment indicated that dietary supplementation of CS61 culture may improve growth performance and feed conversion efficiency in chickens through its anti-inflammatory effect.