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- 저자 : Asif Javed (검색결과 4 건)
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Asif Javed,Musaddaq Azeem,Jakub Wiener,Monica Thukkaram,Jana Saskova,Tariq Mansoor 한국섬유공학회 2021 Fibers and polymers Vol.22 No.1
Zinc oxide (ZnO) nano particles have great importance in textile industry, because of remarkable efficiency andmultiple applications such as antibacterial, UV protection, self-cleaning etc. The aim of this research work was in situ growthof ZnO nano particles on 100 % cotton fabrics with the help of ultrasonic acoustic waves. Zinc nitrate hexahydrate[Zn(NO3)2·6H2O] and sodium hydroxide (NaOH) were used as precursors for ZnO growth. Scanning electron microscopy(SEM), Energy-dispersive X-ray spectroscopy (EDS), X-ray powder diffraction (XRD), Fourier-transform infraredspectroscopy (FTIR) were done to examine the surface morphology and characteristics of deposited nano particles. Furthermore the functional properties i.e. antibacterial, UPF rating, self cleaning, air permeability and bending rigidity of thedeveloped samples were evaluated. The results regarding SEM, EDS, XRD and FTIR confirmed the deposition of ZnO nanoparticleson cotton fabric with pure hexagonal wurtzite crystalline structure. The developed samples showed excellent resultsfor antibacterial, UPF rating and self cleaning with increased bending rigidity and slightly decreased in air permeability.
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Genetic signature of strong recent positive selection at interleukin-32 gene in goat
Akhtar Rasool Asif,Sumayyah Qadri,Nabeel Ijaz,Ruheena Javed,Abdur Rahman Ansari,Muhammd Awais,Muhammad Younus,Hasan Riaz,Xiaoyong Du 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.7
Objective: Identification of the candidate genes that play key roles in phenotypic variations can provide new information about evolution and positive selection. Interleukin (IL)-32 is involved in many biological processes, however, its role for the immune response against various diseases in mammals is poorly understood. Therefore, the current investigation was performed for the better understanding of the molecular evolution and the positive selection of single nucleotide polymorphisms in IL-32 gene. Methods: By using fixation index (FST) based method, IL-32 (9375) gene was found to be outlier and under significant positive selection with the provisional combined allocation of mean heterozygosity and FST. Using nucleotide sequences of 11 mammalian species from National Center for Biotechnology Information database, the evolutionary selection of IL-32 gene was determined using Maximum likelihood model method, through four models (M1a, M2a, M7, and M8) in Codeml program of phylogenetic analysis by maximum liklihood. Results: IL-32 is detected under positive selection using the FST simulations method. The phylogenetic tree revealed that goat IL-32 was in close resemblance with sheep IL-32. The coding nucleotide sequences were compared among 11 species and it was found that the goat IL-32 gene shared identity with sheep (96.54%), bison (91.97%), camel (58.39%), cat (56.59%), buffalo (56.50%), human (56.13%), dog (50.97%), horse (54.04%), and rabbit (53.41%) respectively. Conclusion: This study provides evidence for IL-32 gene as under significant positive selection in goat.
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Trends in Stroke Presentations before and during the COVID-19 Pandemic: A Meta-Analysis
Noman Ishaque,Asif Javed Butt,Joseph Kamtchum-Tatuene,Ali Zohair Nomani,Sarah Razzaq,Nida Fatima,Chetan Vekhande,Radhika Nair,Naveed Akhtar,Khurshid Khan,Maher Saqqur,Ashfaq Shuaib 대한뇌졸중학회 2022 Journal of stroke Vol.24 No.1
Background and Purpose There are reports of decline in the rates of acute emergency presentations during coronavirus disease 2019 (COVID-19) pandemic including stroke. We performed a meta-analysis of the impact of COVID-19 pandemic on rates of stroke presentations and on rates of reperfusion therapy. Methods Following the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines, we systematically searched the literature for studies reporting changes in stroke presentations and treatment rates before and during the COVID-19 pandemic. Aggregated data were pooled using meta-analysis with random-effect models. Results We identified 37 observational studies (n=375,657). Pooled analysis showed decline in rates of all strokes (26.0%; 95% confidence interval [CI], 22.4 to 29.7) and its subtypes; ischemic (25.3%; 95% CI, 21.0 to 30.0), hemorrhagic (27.6%; 95% CI, 20.4 to 35.5), transient ischemic attacks (41.9%; 95% CI, 34.8 to 49.3), and stroke mimics (45.6%; 95% CI, 33.5 to 58.0)during months of pandemic compared with the pre-pandemic period. The decline was most evident for mild symptoms (40% mild vs. 25%–29% moderate/severe). Although rates of intravenous thrombolytic (IVT) and endovascular thrombectomy (EVT) decreased during pandemic, the likelihood of being treated with IVT and EVT did not differ between the two periods, both in primary and in comprehensive stroke centers (odds ratio [OR], 1.08; 95% CI, 0.94 to 1.24 and OR,0.95; 95% CI, 0.83 to 1.09, respectively). Conclusions Rates of all strokes types decreased significantly during pandemic. It is of paramount importance that general population should be educated to seek medical care immediately for stroke-like symptoms during COVID-19 pandemic. Whether delay in initiation of secondary prevention would affect eventual stroke outcomes in the long run needs further study.
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Shazra Khalid,Aneela Iqbal,Asif Javed,Jamshaid Rashid,Ihsan ul Haq,Mohamed Abou El-Fetouh Barakat,Rajeev Kumar 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.11
Industrialization and urbanization have increased the demand for petroleum hydrocarbons; hence the likelihood of contamination of air, soil, and water bodies increases. The survival and biodegradation capabilities of fifteen bacterial isolates were tested in a harsh diesel environment. The bacteria were isolated from soil samples and identified by 16S rRNA gene sequencing. The biodegradation capability of isolates was performed in batch experiments, and diesel degradation analyses were conducted on gas chromatography-mass spectroscopy (GC-MS). The results revealed that only two bacterial isolates (A1 and E5) sufficiently consumed diesel hydrocarbons as a carbon-based energy source. 16S rRNA sequencing identified both isolates as Bacillus genera. An average of 60% of 3% (v/v) diesel was degraded in about 16 hours. Bacillus sp. E5 strain could degrade about 72% and 68% heavier compounds of C24 and C26. The Monod kinetic model for Bacillus sp. E5 utilizing diesel as a substrate showed maximum specific bacterial growth rate (μmax) as 0.1131 hr-1 at 1%, while 0.1287 hr-1 for 3% diesel. Results suggest that the isolated bacterial strain Bacillus sp. E5 has bioremediation potential and can be used as an alternative method for cleaning contaminated petroleum hydrocarbon field sites for sustainable development.
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