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      저자 : Archana Angrup (검색결과 1 건)
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        Manuka Honey versus Antibiotic Ear Drops in Healing of Post-Operative Mastoid Cavity: A Prospective Randomized Trial

        Niveditha Damodharan,Roshan Kumar Verma,Archana Angrup,Naresh K Panda,Naresh K Panda 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.5

        Background and Objectives This study investigates the role of manuka honey in the healingof postoperative mastoid cavity. Subjects and Method This was a single centre prospective study on 40 consecutive patientsof chronic otitis media undergoing canal wall down mastoidectomy. Manuka honey soaked ingel foam was kept in the mastoid cavity for the study group and antibiotic soaked gel foam waskept for the control group. Culture swabs from mastoid granulations were sent at various timesfrom both groups. The healing of the mastoid cavity was assessed in the follow up period. Results Preoperatively 15 out of 20 patients (75%) had a positive aural swab culture in thestudy group while 11 out of 20 (55%) in the control group had a positive aural swab culture. Themost common organism isolated was Pseudomonas aeruginosa and Proteus mirabilis. Onemonth after mastoidectomy only 4 patients (20%) had sterile culture and 16 patients (80%) hadgrown organisms; in the control group, 7 patients (35%) had sterile culture and 13 patients (65%)had growth on culture. The mean merchant scores for the study group and the control were 2.61(2-5) and 2.05 (1-4), respectively. At 3 months 13 patients (65%) with sterile culture and 7 patients(35%) had growth on culture; in the control group, 16 patients (80%) had sterile cultureand 4 had shown persistent growth on culture (p=0.28). All positive cultures were aerobic inboth groups. The mean merchant scores for the study group and the control were 1.03 (0-4)and 0.7 (0-3), respectively (p=0.09). Conclusion Healing of mastoid cavity was almost similar in both groups (p>0.05). Manukahoney exhibited antibacterial activity against Pseudomonas, Proteus, Klebsiella, Escherichiacoli, Staphylococcus

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