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Amaresh Maiti,Nithar Ranjan Madhu,Chanchal Kumar Manna 셀메드 세포교정의약학회 2013 TANG Vol.3 No.2
The paper provides a brief account of 11 plant species used by the tribal people of the district Purulia, West Bengal, India. Most of the plant species are common in this district and some have not been reported earlier for abortive purposes, pharmacology for preparation of medicines for antifertility. All these data were obtained from the tribal medicine men (ojha). At least 10 interview reports of various tribal medicine men were recorded. Parts of various medicinal plants were observed personally, collected and preserved as herbarium specimens for proper identification. The reports of various indigenous methods may help to give some clue in searching the potent contraceptives.
Dash Sujit,Kanungo Sunil Kumar,Mishra Bishwanath,Sahoo Amaresh Chandra,Senapati Aswini Kumar,Pattnaik Sangyarani 경희대학교 융합한의과학연구소 2021 Oriental Pharmacy and Experimental Medicine Vol.21 No.4
PCOS is considered as common endocrine diseases among the females in their regenerative age. The purpose of the study was to analyze phytochemicals by GC–MS followed by the pharmacological evaluation of Sukumaram Kasayam on PCOS induced rats. GC–MS analysis of Sukumaram Kasayam was accomplish to identify phytoconstituents. Twenty-four female rats were used (n = 6/group) in the study consisting of healthy control (Group-I). The experimental groups were divided into 3 subgroups, including rats with PCOS which received no treatment (Group-II), PCOS group (Group-III and Group-IV) was administered daily dose of Clomifene citrate 200 mg/kg and Sukumaram Kasayam 0.5 ml/kg for 3 weeks, respectively. In all experimental groups, oral dose of 1 mg/kg letrozole for 21 days to induce PCOS. After treatment period, rats were anesthetized, blood sex hormone and lipid profile was carried. The GC–MS analysis identified Butane, 1, 1-diethoxy-3-, (+)-2-Bornanone abundant compound in formulation. The PCOS induced rats were treated with Clomiphene citrate, Sukumaram Kasayam, the testosterone decreased significantly (P < 0.01), progesterone increased significantly (P < 0.01), estradiol increased significantly (P < 0.01), the serum LH decreased (P < 0.05), the FSH levels were decreased significantly (P < 0.01). In case of the lipid profile the result showed that the triglyceride, cholesterol, LDL decreased significantly (P < 0.01), whereas the HDL increased significantly (P < 0.01) in comparison to PCOS control rats. Results concluded that Sukumaram Kasayam has beneficial effect on levels of the testosterone, progesterone, estradiol, LH, and FSH in alleviating the complications of PCOS.
Sudhansu Ranjan Das,Debabrata Dhupal,Amaresh Kumar 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.10
This experimental investigation deals with dry hard turning of AISI 4140 steel using PVD-TiN coated Al2O3+TiCN mixed ceramic inserts. The combined effect of cutting parameters (cutting speed, feed and depth of cut) on performance characteristics such as surfaceroughness and flank wear is explored by Full factorial design (FFD) and analysis of variance (ANOVA). The results show that feed is theprincipal cutting parameter influencing surface roughness, followed by cutting speed. However, flank wear is affected by the cuttingspeed and interaction of feed-depth of cut, although depth of cut has not been found statistically significant, but flank wear is an increasingfunction of depth of cut. Observations are made on the machined surface, and worn tool by Scanning electron microscope (SEM) toestablish the process. Abrasion was the major wear mechanism found during hard turning within the studied range. The effect of toolwear on surface roughness was also studied. The experimental data were analyzed to predict the optimal range of surface roughness andflank wear. Based on Response surface methodology (RSM), mathematical models were developed for surface roughness (Ra) and flankwear (VB) with 95% confidence level. Finally, under optimum cutting conditions (obtained by response optimization technique), tool lifewas evaluated to perform cost analysis for justifying the economic viability of coated ceramic inserts in hard turning. The estimated machiningcost per part for TiN coated ceramic was found to be lower (Rs. 12.31) because of higher tool life (51 min), which results in thereduction of downtime and increase in savings.