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RISS 인기검색어
- 검색키워드
- 저자 : Aline C. C. Tritto (검색결과 1 건)
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Aline C. C. Tritto,Mariane T. Amano,Maria E. De Cillo,Vinicius A. Oliveira,Sandro H. Mendes,Caroline Yoshioka,Hamilton Roschel,Niels Olsen S. Camara,Bruno Gualano,Guilherme G. Artioli 한국운동재활학회 2018 JER Vol.14 No.1
The role of plasma glutamine concentration and glutamine supplemen-tation on immunosuppression was investigated in combat athletes. Twenty-three male athletes were randomly assigned to receive gluta-mine (21 g/day, n=12) or placebo (ovalbumin, n=11) for 10 days. Six athletes who did not lose weight served as controls. Athletes were as-sessed 21 days before (-21d), 1 day before (-1d) and 5 days after (+5d) a competition. Weight reduction was similar between glutamine (-8.2%± 4.1%) and placebo (-8.5%±2.4%) and negligible in control (-0.6%±1.4%). In both weight-loss groups, the majority of athletes reported symptoms of upper respiratory symptoms, as assessed by the Wisconsin upper respiratory symptom survey questionnaire. Only two athletes reported symptoms in the control group. Immune cell function remained un-changed throughout the study except for an increase in neutrophil phagocytic activity (placebo: -21d=5,251±2,986; -1d=17,428±22,374; +5d=21,125±21,934; glutamine: -21d=6,096±3,549; -1d=11,029±17,113; +5d=28,186±21,032 FI) and a minor change in monocyte phagocytic activity (placebo: -21d=4,421±3,634; -1d=3,329±6,283; +5d=3,243± 2,553; glutamine: -21d=4,051±3,186; -1d=3,106±2,625; +5d=4,981± 4,598) in both glutamine and placebo after weight loss. Plasma gluta-mine and cortisol remained unchanged across the study. creatine ki-nase levels were increased in placebo (-21d=125.2±54.1; -1d=187.2± 73.5; +5d=111.3±59.1 U/L) but not in glutamine (-21d=136.2±58.2; -1d= 168.8±65.0; +5d=129.7±64.0 U/L). Rapid weight loss increased the fre-quency and severity of infection symptoms, but this was neither associ-ated with plasma glutamine depletion nor counteracted by glutamine supplementation.
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