유전성 비용종증 대장암의 임상적 고찰

서정민,박재갑,최국진,김진복,서정민,박재갑,최국진,김진복 대한대장항문학회 1992 Annals of Coloproctolgy Vol.8 No.2

위암 환자에서 세포성 면역 기능에 관한 연구

이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김삼용,김영건 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1

We performed a variety of lymphocyte stimulation tests, delayed hypersensitivity skin tests, and enumeration of several lymphocyte subpopulations in 21 patients with gastric cancer who did not receive any form of anticancer therapy, and in 20 healthy controls. The gastric cancer patients had significantly decreased number and total score of positive reactions in delayed hypersensitivity skin tests compared with the healthy controls. The percent of CD_(4) positive lymphocytes in the gastric cancer patients was significantly decreased compared to the normal control subjects, but it had no correlation with the total score of delayed cutaneous hypersensitivity reactions. The ratio of helper to suppressor cells was lower in the cancer group. The uptake of 3H-thymidine was markedly depressed in cancer patients when stimulated with various mitogens. There was little correlation between any of the stimulation tests and any of the lymphocyte subpopulation proportions to delayed hypersensitivity cutaneous reactions. Optimal proliferative response was found in lymphocytes stimulated with 10 micrograms of concanavalin-A and 10 microgram of phytohemagglutinin. Advanced stage patients had greatly depressed delayed hypersensitivity skin reactions and proliferative responses to mitogens compared with localized diseases. These results suggest that gastric cancer patients have depressed cellular immune functions, which mainly result from the decreased helper cells and defects in functional proliferative response to mitogens. Interleukin-2 and interferon-gamma restored the in vitro proliferative response of lymphocyte in patients with gastric cancer.

위암 환자에게 세포성 면역 기능에 관한 연구

이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김상용,김영건 忠南大學校 癌共同硏究所 1991 癌共同硏究所 硏究誌 Vol.1991 No.-

鼻毛의 白毛發生에 의한 年齡推定

김진국,홍석찬,진정언,박의우,김동욱 大韓法醫學會 1999 대한법의학회지 Vol.23 No.1

The gray vibrissae of Korean males(n= 189) between 15 and 75 years old and females(n=111) between 15 and 74 years old whop visited the department of otorhinolaryngology, Konkuk university Chungju hospital during 1996 to 1998, were counted for the purpose of estimating approximate age range in individuals of unknown age. The lowest age appearing gray hairs in both sexes was 15-year-old. The Pearson's correlation coefficient in both sexes was 0.490 (p<0.01). The age appearing gray vibrissae in females was slightly earlier than that of males, however, the differences between right and left sides of nasal cavity were insignificant. This method of counting gray vibrissae would be useful to estimate age range in personal identification together with other methods available until now.

비정형 향정신병약물을 투여 중인 정신분열병 환자의 주관적 삶의 질 : 정신병리, 약물 부작용 및 약물에 대한 주관적 반응과의 관련성

김종훈,윤정희,이자영,노경희,홍성극,윤세창,강웅구,김용식 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.2

Objectives : The purpose of this study was to evaluate the characteristics of psychopathology, adverse drug effects, and Subjective response to drugs that have a significant impact on the subjective quality of life in schizophrenic patients receiving atypical antipsychotics. Methods : One hundred and one schizophrenic patients, who were receiving maintenance treatment with atypical antipsychotics, were evaluated. Subjective quality of life was assessed using the standardized Korean modification of a self-rating scale to measure subjective well-being under neuroleptics (KmSWN). Patients' psychopathology was evaluated using the Positive and Negative Syndrome Scale. Adverse effects and subjective response to drug were evaluated using the Liverpool University Neuroleptic Side Effect Rating Scale and the Drug Attitude Inventory-10, respectively. Correlation analysis and stepwise multiple regression analysis were conducted. Results : In psychopathology, the severity of depression and anxiety showed the most significant correlation with the score ofKmSWN. In adverse drug effects, the severity of psychic side effect and extrapyramidal side effect showed the most significant correlation with the score ofKmSWN. Regarding subjective response to drug, significant correlation was observed between the severity of subjective negative response and the score of KmSWN. Stepwise multiple regression analysis revealed that psychic side effect, extrapyramidal side effect, and depression contributed significantly to the total score of KmSWN. These variables accounted for 59.7% of the total variance. Conclusion : The results of the present study suggest that psychic side effect, extrapyramidal side effect and depressive symptom are the clinical characteristics that are significantly associated with the subjective quality of life. An effective management strategy for these variables should be established in developing a treatment program to enhance the quality of life of patients with schizophrenia.

이산 웨이브릿 워터마킹을 이용한 디지털 이미지 보호

김국세,이정기,박찬모,조애리,류천열 조선대학교 전자정보통신연구소 2003 電子情報通信硏究所論文誌 Vol.6 No.1

정보통신의 비약적인 발전에 힘입어 멀티미디어 데이터는 언제 어디서든 전송 받거나 공유할 수 있게 되었다. 아날로그 형태에서 디지털의 아날로그를 형태로 빠르게 대체되고 있으며, 디지털로 신호를 표현하는 방법은 기존 사용하여 표현하는 방법에 비해 많은 장점을 가지고 있다. 하지만 디지털로 된 데이터는 언제 어디서든 대단위 복제가 가능하다. 디지털 영상 정보의 보호를 위해 디지털 워터마크(Digital Watermark)가 있다. 디지털 워터마크는 공개키 알고리즘이나 방화벽 등으로 해독된 영상에 대하여 부가적인 보호를 제공한다. 디지털 영상에 대한 저작권 정보, 배포자 정보 그리고 사용자 정보를 영상에 삽입함으로써 훗날 법적인 문제가 발생하였을 때 해결책을 제시할 수 있다. 본 논문에서는 디지털 영상 데이터의 정보 보호를 위해 주파수 영역에서의 웨이브릿 변환(Wavelet Transform)을 이용한 이미지 적용 디지털 워터마킹(Image-Adaptive Digital Watermarking) 방법을 제안한다. 이미지 적응 웨이브릿(Image-Adaptive Wavelet)은 영상을 주파수적으로 분해하면서 각 대역들의 공간 영역에서의 정보를 함께 지닌고 JND긯(Just noticeable difference)을 포함한다. 이미지 적응 웨이브릿의 이러한 특성을 이용하여 다해상도 분해하고, 손실 압축(Loss Compression)이나 필터링(Fitering), 잡음(Noise)등에 크게 영향받는 저주파 성분과 인간의 시각적으로 큰 의미를 갖는 고주파 성분의 특성을 이용하여 워터마크를 삽입한다.

MGPSCS-A1을 이용한 GPS(Global Position System)에 관한 연구

김정국,박수민 東西大學校 2000 동서논문집 Vol.6 No.-

본 논문에서는, 2000년 5월 1일 자정을 기해 미 백악관의 S/A(Selective Availability) 해제 발표 전과 발표 후 고정 위치에 대한 위치 데이터의 차를 확인하기 위해, GPS의 기초와 GPS 수신기의 모듈 MGPSCS-Al을 소개하고, 그리고 고정 위치에 대한 위치 정보를 반복 측정하여 S/A 해제 전과 후의 오차의 정도를 확인하였다. In this paper, we introduce an introduction to GPS and GPS - based receiver module MGPSCS-Al in order to verify the difference of corresponding position data in terms of iterative measurements of an appropriate fixed point, before and after the S/A released by the announce of US white house at the midnight on May 1, 2000.

방위특징 탐지 단순신경세포들의 배열순서에 관한 연구

김길중,김정국,서광명,서용수 동서대학교부설연구소 1998 연구소 논문집 Vol.3 No.-

Cells in avisual cortex line in columns which are perpendicular to the cortical surface and the cortical cells in a column prefer to respond to an orientation of each line segments of an sesory image. orientation preference of each cortical column is highly correlated to those of nearbycolumns and varies smoothly anlong the surface of the cortex. To elucidate the mechanism of this columnar organization, we propose a simple model consisting of orientation selective neruons(OSNs) with local facilitation and lateral inhibition. it is playsible that modifiable connections play an important role in forming and refining the organization togher with the sensory experience. Thus the feed-forward connections between OSNs and LGN cells are modifiable. The interactions between OSNs in the same layer take place by way of feedback pathways and are excitatory and inhibitory. The behavior of the model is described by a STM equations of Growwberg and critical parameter of negative one dimensional ??G function, σ would give variety to the differences in detected orientations.

Effect of Mechanical Alloying on the Microstructural Evolution of Al60Cr30Si10 Alloys Processed by Spark Plasma Sintering

Jeong‑Han Lee,Ik‑Hyun Oh,Jun‑Ho Jang,Ju‑Hun Kim,Sung‑Kil Hong,Hyun‑Kuk Park 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

In this study, Al, Cr and Si fine powders were alloyed by planetary ball milling to investigate their microstructural evolution,following their mechanical alloying behavior. The formation of Al(Cr) supersaturated solid solution by the Cr grainsembedded in Al-matrix, which contributed substitutional structure is discussed in relation to their structural evolution inaccordance with the distortion of a crystal lattice. The compacts of Al–Cr–Si alloys were prepared by rapid sintering withina short time by dense consolidation above the density of 99.9% as the formation of intermetallics, except in the case of thedistribution of single-phases induced by the Al-melting. The formation behavior of intermetallics was dominated by dependenceon the structures of the milled-powder and subsequent sintering temperature. To estimate the consolidated behaviorsof compacts, various approaches derived from TEM and XRD analysis were taken to obtain microstructural evidences ofthe inter-diffusion, following the presence of thermally stable intermetallics.

Rapid Consolidation of WC‑ZrSiO4 Hard Materials by Spark Plasma Sintering: Microstructure, Densification, and Mechanical Properties

Jeong‑Han Lee,Ik‑Hyun Oh,Ju‑Hun Kim,Sung‑Kil Hong,Hyun‑Kuk Park 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.9

Densely consolidated WC-based hard materials with 5–20 vol% ZrSiO4was fabricated by spark plasma sintering at 1400 ℃ ata constant heating rate of 70 ℃/min−1. To achieve mechanical alloying of WC-ZrSiO4, planetary ball milling was carried outfor 12 h, during which the brittle-brittle components (WC-ZrSiO4) became fragmented and their particles became refined. Itwas observed that certain, specific, non-isothermal sintering kinetics, such as apparent activation energy, sintering exponents,and densification strain, affected the densification behavior. The evolution of phase structure from powder to compact wasfound to be related the lattice distortion and micro-strain in the basal planes of WC. By examining the mechanical propertiesof the samples, it was that the added zircon content leads to enhanced fracture toughness (12.9 MPa m1/2) owing to thepresence of WC-ZrSiO4 in the cemented carbide. In fact, the microcrack propagation of the fracture passed through zirconfrom a transgranular to a ductile component (fcc) where the crack tips could be absorbed.