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( Keonhee Lee ),( Myoungeun Choi ),( Chonghyun Won ),( Sungeun Chang ),( Miwoo Lee ),( Jeeho Choi ),( Woojin Lee ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Advances in medicine have led to the development of immunomodulatory drugs such as Anti-CTLA-4 agents and anti-PD-1/PD-L1 agents for treating patients with advanced-stage malignancies. Here, we describe a 53-year-old male patient with metastatic esophageal cancer, who was treated with nivolumab, an anti-PD-1 agent, and developed multiple subcutaneous nodules on his lower extremities which were diagnosed as septal panniculitis consistent with erythema nodosum on histopathologic examination. Interestingly, the subcutaneous lesions began to regress after biopsy and did not require any additional immunosuppressive therapy. Our case implies that dermatologic toxicities are diverse, and physicians should be vigilant regarding new side effects of immunomodulatory drugs, as recognizing such events will lead to early and proper management of patients.
A case of lymphomatoid contact dermatitis secondary to hair dye
( Keonhee Lee ),( Myoungeun Choi ),( Sungeun Chang ),( Miwoo Lee ),( Jeeho Choi ),( Woojin Lee ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Lymphomatoid contact dermatitis is a subset of cutaneous pseudolymphoma that clinically and histopathologically resembles both allergic contact dermatitis and cutaneous lymphoma. A variety of allergens have been described since the first description of this entity in 1976. Typically lymphomatoid contact dermatitis is related to T cell hyperplasia. We herein describe a case of cutaneous B-cell lymphoid contact dermatitis caused by hair dye. This case demonstrates that lymphomatoid contact dermatitis can present with various clinical features and emphasizes that thorough history-taking and examination is important for the diagnosis.
( Keonhee Lee ),( Myoungeun Choi ),( Changjin Jung ),( Chonghyun Won ),( Sungeun Chang ),( Miwoo Lee ),( Jeeho Choi ),( Woojin Lee ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Background: Gordonia species were recently found to cause human infection. Most Gordonia bronchialis infections are associated with sternal wounds and foreign bodies. Case presentation: Here, we present a case of a cutaneous firm nodule caused by G. bronchialis on an immunocompetent patient’s lower extremity after receiving acupuncture. Conclusion: Our present case indicates spontaneous cutaneous infection of G. bronchialis can develop even in a healthy patient. With the popularity of complementary and alternative medicine, physicians should be aware that G. bronchialis infection can be associated with oriental medicine similar to mycobacterial infection. Recognizing the diverse clinical features of newly emerging Gordonia species will facilitate appropriate diagnosis and management of future patients.