홍잠의 다양한 건강 증진 기능성에 대한 연구 현황

이현태,Lee, Hyun-Tai 한국잠사학회 2019 한국잠사곤충학회지 Vol.55 No.2

Mature silkworms (MS) of Bombyx mori have enlarged silk glands, which are known to be enriched with various functional materials. A special steaming method has been developed for processing MS with enlarged silk glands edible, by which the MS have become a potential health supplement for improving the quality of life. Steamed and lyophilized MS powder (SMSP) has been strongly believed to have various unidentified beneficial effects for humans. Therefore, the purpose of this mini-review is to summarize the various health promoting functionalities of SMSP, which have been published in the paper so far. Firstly, SMSP increased healthspan as well as lifespan, locomotor ability, and resistance to Parkinson's disease by enhancing olfaction and mitochondrial activity in neurons. Secondly, SMSP increased resistance to carcinogens causing liver cancers, improved both acute and chronic liver function with alcohol metabolism, and prevented alcohol induced stomach ulcers. Thirdly, SMSP reduced UVB-induced skin pigmentations and melanogenesis. Taken together, SMSP can be regarded as a promising natural health product to increase incomes for sericultural farm households in Korea as well as global human health and welfare.

Design and Construction of a FFT Analyzer Using a Microcomputer

이현태,김중규,이상배,Lee, Hyeun Tae,Kim, Jung Gyu,Lee, Sang Bae The Institute of Electronics and Information Engin 1986 전자공학회논문지 Vol.23 No.6

By improving the ability of arithmatic processing with an arithmatic processor in a microcomputer and realizing the data input system for real time analysis, an FFT analyzer that is usable within the range of audio frequency is designed and constructed. The input signal passes through a gain programmable pre-amplifier and anti-aliasing lowpass filter into an analogditital converter to be converted into digital form. The converted input data is processed by an Apple II microcomputer. The results of the processing are displayed using a microcomputer display unit and can be copied on a printer or stored in a floppy disk.

시장개방에 따른 손보업계의 당면과제

이현태,Lee, Hyeon-Tae 한국화재보험협회 1986 防災와 保險 Vol.28 No.-

카포시 육종과 동반된 Idiopathic CD4 + T Lymphocytopenia

이현태,장호선,권경술,정태안 ( Hyun Tae Lee,Ho Sun Jang,Kyung Sool Kwon,Tae Ahn Chung ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1

Idiopathic CD4+ T lymphocytopenia(ICL) is a new disease entity characterized by depletion of helper T cells apparently without any evidence of HIV infection. We report a case of ICL associated with Kaposis sarcoma(KS) and pneumocystis carinii pneumonia(PCP) in a 34-year old woman. She developed violaceous, protruding masses on scalp, back, both extremities, palms, soles, left. first toe and peritonsillar region for 2 months. These lesions were confirmed as KS by histopathologic findings. Chest X-ray and HRCT findings represented PCP and KS. Absolute deficiency of CD4+ T cell was detected in the count of T cell subsets. Serologic tests for HIV-1, 2 and HTLV I, -II were negative. And she was absent any defined immunodeficiency or therapy associated with decreased levels of CD4+ T cells. By CDC criteria, a diagnosis of ICL was made. Because of aggravation of PCP and lung involuement of KS, she died at 22nd day after admission. (Kor J Dermatol 1997;35(1): 191-195)

전두부에 발생한 다발성 피지선암

이현태,장호선,권경술,정태안,오창근 ( Hyun Tae Lee,Ho Sun Jang,Kyung Sool Kwon,Tae Ahn Chung,Chang Keun Oh ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.4

Sebaceous carcinoma is a rare, aggressive, malignant tumor derived from the adnexal epithelium of sebaceous glands. This tumor occurs most frequently on the eyelids, but may occur on the extraoccular sites. Clinically, it is presented as a solitary tumor in most cases and very rarely as multiple ones. We report a case of multiple. sebaceous carcinomas on the frontal region in a 73 year-old man. He had well-demarcated, reddish, asymptomatical, protruding masses on the frontal region for 2 months. The histopathologic findings showed irregular, variable sized, lobular tumor nests of the entire dermis, and each lobule was composed of foamy cytoplasmic atypical cells and undifferentiated cells containing, eosinophilic cytoplasm. He was treated with surgical excision and no recurrence was observed during 6 months. (Kor J Dermatol 1997;35(4): 824 - 829)

대전광역시 재난 및 안전 관리 체제의 현황과 개선 과제

이현태,Lee, Hyeon-Tae 대전발전연구원 2014 대전발전포럼 Vol.49 No.-

황색종에 대한 임상 및 병리조직학적 관찰

이현태,권경술,장호선,정태안,오창근 ( Hyun Tae Lee,Kyung Sool Kwon,Ho Sun Jang,Tae Ahn Chung,Chang Keun Oh ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.5

Background: Xanthomas consist of localized infiltrates af lipid-containing histiocytic foam cells that are usually found within the dermis or tendons. They frequently arise in the presence of a disturbance of lipid metaholism. Objective : The purpose of this study was to elucidate the clinical and histopathological characteristics of xanthomas. Methods : Eighteen cases of xanthoma confirmed clinically and histopathologically were ana lyzed. Xanthelasma was excluded in this study. Results : The results were summarized as follows. 1. The incidence of xanthoma was 0.03% of the total number of dermatologic patients. 2. The ratio between male and female was 1:2.6 and the age distribution varied from 2 to 65 years old(mean age : 37.4 years-old), and the distribution of age of onset was from birth to 62 years old(mean age of onset: 32.9 years old). 3. The frequencies of elinical types, in descending order, were xanthoma tuberosum(XT) 44.4%, xanthoma planum(XP) 27.8%, Xanthoma eruptivum(XE) 22.2%, and xanthoma striatum palmare (XSF) 5.6 % . 4. The common sites were the knee, elbow and buttock in XT; The upper and lower extremities in XE, the cheek, neck and chest in XP; palmar creases in XSP. 5. Serum lipid abnormalities were detected in 88.9%(16/18). 6. The associated diseases were hypothyroidism, diabetes, hepatomegaly, psoriasis. 7. A family history was significant in 2 patients with XT. 8. The associated hyperlipoproteinemia was type IIa(4/8), IIb(2/8), III(1/8), IV(1/8) in XT, type IIa(2/5), IV(2/5) and normolipoproteinemia(1/5) in XP, type I(1/4), IV(1/4), V(1/4) and normolipoproteinmia(1/4) in XE, type III(1/1) in XSP, respectively. 9. Diet, alone or combination with antilipidemic drugs were used for treatment, and the lesions were cleared in 2(one XP and one XE) of 7 patients that could be followed up. 10. Histopathological features revealed that lipid-laden foamy histiocytes were observed in all cases of xanthomas and foreign body giant cells were more common than Touton giant cells. Conclusion : Xanthomas were not so common disorders compared with the incidence of hyperlipoproteinemia and were more common in females than males. The most common clinical type was XT except for xanthelasma. The most common associated hyperlipoproteinemia in each type of xanthoma was type II in XT, type IIa and IV in XP, variable types in XE, type III in XSP, respectively. Lipid-laden foamy histiocytes were observed in all cases of xanthomas and for eign body giant cells were more common than Touton giant cells. (Korean J Dermatol 1997;35(5): 940-946)

임베디드 보드를 이용한 미아 위치 정보 시스템

이현태(Lee, Hyeon-Tae),이구연(Lee, Goo-Yeon) 강원대학교 산업기술연구소 2009 産業技術硏究 Vol.28 No.B

In this paper, we implement a place information system for missing children using embedded board. In the implementation, the embedded board receives location information from GPS satellites, parsing GGA information which includes current time and location coordinates from the satellite information and sends them to the location management server. The server locates a missing child using the location information from embedded board together with server database. We implement an application program for the system. The program shows current location of a child and its moving path and browses the corresponding map from coordinates mapping.

삼선건설과 판즈화

이현태(Lee Hyuntai) 역사비평사 2016 역사비평 Vol.- No.117

This paper analyzes Panzhihua construction on ‘the Third Front’ in the Chinese socialist era during the 1960s and 70s; the background, process, features, shortcomings and lessons are reviewed. Panzhihua was a unique achievement of urbanization in the Chinese socialist era. However, it was not sustainable or reproducible because of the failure to improve citizen’s lives, the collapse of the centrally-planned economy, and the prevalence of capitalism throughout the world. Nevertheless, Panzhihua is a good subject of research in order to understand the past, present and future of urbanization in the pre-socialist bloc and developing countries. Moreover, it provides a useful lesson for resource-poor developing countries that attempt to achieve rapid urbanization by focusing scare resources on building cities.

용담 열수 추출물이 위장관 운동 기능 저해 상황에서 위장관 이송률에 미치는 영향

이현태(Hyun-Tai Lee) 한국생명과학회 2019 생명과학회지 Vol.29 No.12

한약재로 쓰이는 용담(Gentiana scabra)의 열수 추출물(GS-W)을 정상 마우스에 경구 투여할 경우 in vivo 위장관 이송률(ITR)이 유의적이고 용량 의존적으로 증가한다는 사실이, 최근 본 연구진에 의해 보고된 바 있다. 이에 본 연구에서는, in vivo 실험적 위장관 운동 기능 저해(GMD) 마우스 모델에서는 GS-W가 ITR에 어떠한 영향을 미치는지 검정하고자 하였다. GS-W는 5 g/kg의 고용량 경구 투여 시에도 정상 마우스에서 급성 독성을 나타내지 않았고, GMD 마우스에서 ITR을 유의적이고 용량 의존적으로 증가시켰으며, 특히 1 g/kg 경구 투여 시의 ITR은 cisapride 투여 시보다 수치 상으로 높았다. 이러한 결과들은, 1990년대까지 임상적으로 널리 처방되었으나 치명적인 부작용으로 인해 2000년 이후 시장에서 철수된 약물인 cisapride를 GS-W가 대체하여, 인간의 다양한 GMD 상황을 예방하거나 그 증상을 완화시킬 수 있는 잠재력이 있음을 시사한다. Our recent study has revealed that in vivo intestinal transit rate (ITR) in normal mice was significantly increased by the administration of an aqueous extract of dried Gentiana scabra rhizomes and roots (GS-W) in a dose-dependent manner. Following on from our previous study, the effect of GS-W on ITR was measured in mice with experimentally induced gastrointestinal motility dysfunctions (GMDs) in the present study. GS-W showed no significant acute toxicity even at an oral dose of 5 g/kg to mice. ITR was significantly retarded in the GMD mice compared with that in normal mice, and this retardation was significantly recovered by the oral administration of GS-W in a dose-dependent manner. Furthermore, the ITR value of GS-W at a dose of 1 g/kg appeared to be higher than that of cisapride, which was predominantly prescribed for human patients with various GMDs in the late 1900s but was withdrawn from the market in 2000 due to its fatal side effects. The current results suggest that GS-W is a potential substitute for cisapride to prevent or alleviate human GMDs.